Financial Data and Key Metrics Changes - Revenue in Q1 2025 totaled $73.5 million, down from $76.2 million in Q4 2024, with negligible revenue from COVID-19 testing [21] - GAAP gross margin was 38.6%, while non-GAAP gross margin was 41%, showing year-over-year improvement due to operational efficiencies [21][22] - Total GAAP operating expenses were $48.1 million, slightly up from $48 million in Q4 2024, with non-GAAP operating expenses remaining flat at $37.4 million [22] - Adjusted EBITDA loss for Q1 was approximately $2.9 million, an improvement from a loss of $3.2 million in Q1 2024 [23] - The company ended Q1 with approximately $814.6 million in cash, cash equivalents, restricted cash, and marketable securities [23] Business Line Data and Key Metrics Changes - Precision diagnostics revenue increased by $6.7 million or 17.8% year-over-year, while anatomic pathology revenue rose by $2.2 million or 9.5% year-over-year [13] - Biopharma services revenue grew by $1.4 million or 51.3% year-over-year, although it experienced a sequential decline of 33.7% due to contract timing [14] - The growth in precision diagnostics was driven by reproductive health services and expanded carrier screening, with new client wins contributing significantly [14][15] Market Data and Key Metrics Changes - The company is seeing significant usage from new VA hospitals and positive momentum from partnerships, particularly with Foundation Medicine [14][15] - The biopharma services business is expected to experience variability quarter-to-quarter, but the company anticipates continued demand due to improved product offerings [19] Company Strategy and Development Direction - The company is focused on expanding its laboratory services and therapeutic development pipeline, with ongoing clinical trials for candidates FID-seven and FID-twenty two [10][11] - Investments in digital pathology and AI are expected to enhance operational efficiency and quality [18] - The company is evaluating potential M&A opportunities to enhance its distribution network and technology deployment [37] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about the fundamentals in 2025, with expectations for core revenue to reach approximately $310 million, representing a 10% year-over-year growth [24] - Non-GAAP gross margins are expected to slightly exceed 40% for the full year, with anticipated cash burn for therapeutics development around $25 million [26] - The company aims to manage spending while focusing on capital allocation to support growth initiatives [27] Other Important Information - The company has repurchased approximately 646,000 shares at a cost of $10.9 million since the beginning of 2025, with a total of $110.4 million spent since the inception of the repurchase program [23][27] - The SEC investigation concluded with no enforcement action recommended, resulting in a reversal of a previously accrued liability of $1 million [22] Q&A Session Summary Question: Why not raise the full year guidance despite good momentum? - Management prefers to be more comfortable before adjusting guidance, aiming for considerable changes rather than minor adjustments [30][31] Question: How much of Q1 results came from new accounts in precision diagnostics? - The strong performance was driven by both existing clients and new client wins, with ongoing onboarding processes for larger clients [32][34] Question: Expectations for stock buybacks and M&A potential in 2025? - The company is actively deploying capital for stock buybacks and evaluating M&A options to enhance distribution and technology [36][37] Question: Expected penetration rate for FID-one hundred seven and its market potential? - The initial focus is on head and neck cancer, with potential for broader applications post-trial [39] Question: Thoughts on capital deployment for expanding sales and marketing? - Sales and marketing expenses are expected to increase as the company hires new personnel across various divisions [41][42]

Company to Host Conference Call with Live Q&A, May 14, 2025, at 4:30pm ET / 22:30 CET IRVINE, California – April 30, 2025 (GlobeNewswire) – MDxHealth SA (NASDAQ: MDXH), a leading precision diagnostics company, today announced it will release its financial results for the first quarter ended March 31, 2025, after market close on Wednesday, May 14, 2025. Title:Mdxhealth Presents First Quarter 2025 Financial Results andCorporate Update Conference Call and WebcastSpeakers:Michael K. McGarrity, Chief Executive ...