Core Insights - Smith+Nephew announces findings from a comparative study of single-use negative pressure wound therapy (sNPWT) devices, highlighting the benefits of PICO sNPWT in reducing surgical site complications [1][2] Study Findings - The study analyzed data from over 22,000 patients, showing that prophylactic use of PICO sNPWT (-80 mmHg) significantly reduces the risk of wound dehiscence, hospital length of stay (LoS), and overall healthcare costs compared to Prevena sNPWT (-125 mmHg) [2][4] - Key findings include a 57.8% relative reduction in wound dehiscence risk, a 9.1% relative reduction in LoS (6.33 days vs. 6.86 days), and a 10.34% relative reduction in admission-related costs [6] Economic Impact - The use of PICO sNPWT is associated with substantial cost savings, particularly for patients with comorbidities such as obesity, diabetes, and hypertension, contributing to reduced surgical site complications and improved health economic outcomes [5][6] Clinical Recommendations - The findings support the growing evidence for the prophylactic use of incisional negative pressure wound therapy (iNPWT) across various surgeries, aligning with global recommendations from NICE, WHO, and ACS/SIS guidelines [7]