Summary of AVITA Medical FY Conference Call Company Overview - **Company**: AVITA Medical (NasdaqCM:RCEL) - **Industry**: Acute wound care, specifically focused on hospital-based treatments for burns, surgical wounds, and traumatic wounds [2][3] Core Products - **RECELL**: Flagship product for acute wound care, evolving from a manual to an automated process (RECELL GO and RECELL GO mini) [4][5] - **Cohealyx**: Collagen dermal matrix that prepares the wound bed for grafting, offering quicker vascularization compared to competitors [5][6] - **PermeaDerm**: Temporary biosynthetic matrix that protects and allows observation of the wound during healing [6][7] Market Dynamics - **Target Market**: Approximately 200 accounts in the U.S. with a Total Addressable Market (TAM) of $3.5 billion, focusing on a strategic TAM of $1.3 billion [11] - **Market Penetration**: Currently less than 5% across the portfolio, with RECELL at about 15% penetration [11][12] - **International Expansion**: Efforts in Australia, Japan, and Europe, with recent attention due to a Swiss nightclub fire highlighting the need for better treatment options [12][13] Financial Performance - **Growth Rate**: Achieved 11% growth in the previous year despite challenges, with expectations for sequential growth throughout 2026 [14][15] - **CAGR**: Company has experienced a compound annual growth rate of close to 30% over the last five years [14] - **Cost Management**: Focus on cost discipline while aiming for revenue growth, with strategic reductions in the sales force [15][16] Reimbursement Challenges - **Reimbursement Dynamics**: Ongoing issues with reimbursement from CMS and MACs, with about 70%-80% recovery expected in the near term [30][35] - **Impact on Sales**: Delays in reimbursement have caused confusion and disruption, but clarity is expected to improve in the coming months [33][34] Strategic Focus - **Product Adoption**: Emphasis on increasing penetration in existing accounts and expanding usage among different types of wounds and physicians [40][61] - **Clinical Studies**: Ongoing post-market studies for Cohealyx and PermeaDerm, with results expected to support product adoption [7][13] - **Sales Strategy**: A clinically based sales team that acts as consultants to surgeons, enhancing familiarity with products [62][63] Economic Benefits - **Speed to Healing**: RECELL allows patients to heal and be discharged 36% sooner, providing economic advantages for hospitals [53][72] - **Cost Savings**: Transitioning from allograft to PermeaDerm can save hospitals significant costs, as highlighted by a physician's estimate of $500,000 in annual savings [87] Profitability Outlook - **Margin Expectations**: Cohealyx and PermeaDerm expected to have around 50% margins, while RECELL will maintain higher margins in the low 80s [92] - **Path to Profitability**: Anticipated growth trajectory suggests that profitability is on the horizon if current trends continue [93] Conclusion - **Future Outlook**: AVITA Medical is positioned for growth with a strong focus on execution and product adoption, expecting to discuss improved financial metrics throughout the year [97]

AVITA Medical®, Inc | Cary Vance, Interim CEO J.P. Morgan Healthcare Conference (ASX: AVH, NASDAQ: RCEL) Forward-Looking Statements & Legal Disclaimers This presentation and the accompanying oral commentary may contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These statements are predictions and subject to significant risks and uncertainties that could cause actual results to differ materially from those expressed or implied. Forward-looking stat ...

Core Insights - AVITA Medical has transitioned from a single-product company focused on burn treatment to a multi-product platform in the therapeutic acute wound care market, with a market opportunity expanding from $455 million to over $3.5 billion [3][6]. Financial Performance - For Q1 2025, AVITA Medical reported commercial revenue of $18.5 million, a 67% increase from $11.1 million in Q1 2024, driven by deeper customer penetration and new product launches [6][9]. - The gross profit margin for the quarter was 84.7%, down from 86.4% in the same period last year, primarily due to volume discounts and product mix [10]. - Total operating expenses increased to $27.5 million from $26.8 million in Q1 2024, with a notable rise in sales and marketing expenses [11]. Product Developments - The company launched RECELL GO mini in February 2025, targeting smaller wounds in U.S. trauma centers, and initiated the nationwide launch of Cohealyx on April 1, 2025 [6][9]. - AVITA Medical aims to drive adoption of RECELL GO and Cohealyx while continuing to develop clinical data for its products [7]. Future Guidance - The company expects full-year 2025 commercial revenue to be between $100 million and $106 million, reflecting a growth of approximately 55% to 65% compared to 2024 [7]. - AVITA Medical anticipates generating free cash flow in the second half of 2025 and achieving GAAP profitability in Q4 2025 [7]. Cash Position and Liabilities - As of March 31, 2025, AVITA Medical had approximately $25.8 million in cash and marketable securities, with a waiver secured for the first quarter trailing 12-month revenue covenant [14]. - Total liabilities stood at $74.1 million, with long-term debt at $41.5 million [23].