RNA interference therapeutics
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Backdoor AI Beneficiary Yields 8.8%, Trades at 13% Discount
Investing· 2025-11-26 10:20
Core Insights - The article discusses the transformative impact of AI on the pharmaceutical industry, particularly in drug development timelines and profitability [1][3][12] - It highlights the potential for significant returns from investments in companies benefiting from accelerated drug development cycles, specifically mentioning an 8.8% dividend yield from BlackRock Health Sciences Term Trust (BMEZ) [5][4] Industry Overview - AI is expected to reduce drug development time from the traditional 10-15 years to approximately 3-6 years, enhancing monopoly pricing periods for pharmaceutical companies [2][3] - The faster drug discovery process will lead to an increase in viable drug candidates entering trials, resulting in more approved medications and improved cash flow for these companies [4][12] Company Focus - BMEZ is a closed-end fund that invests in companies directly benefiting from advancements in pharmaceutical research and development, particularly those utilizing AI [5][8] - Alnylam Pharmaceuticals, a top holding of BMEZ, specializes in RNA interference therapies and is positioned to leverage AI for faster and more effective research outcomes [8][9] Market Dynamics - BMEZ currently trades at a 13% discount to its net asset value (NAV), presenting a buying opportunity given the strong fundamentals of the sector [5][7] - The article notes that despite recent regulatory challenges and market sentiment against drug developers, the political landscape is shifting favorably for pharmaceutical companies, allowing for longer patents and expedited review processes [10][11][12]
Does Alnylam Pharmaceuticals (ALNY) Have the Potential to Generate Strong Long-Term Growth?
Yahoo Finance· 2025-09-25 13:18
Group 1 - Parnassus Mid Cap Growth Fund reported a return of 13.29% in Q2 2025, underperforming the Russell Midcap Growth Index which returned 18.20% [1] - The Fund's performance was negatively impacted by stock selection in the Industrials and Information Technology sectors, while holdings in the Financials sector contributed positively [1] - The Fund highlighted Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) as a key stock, which has shown a one-month return of 1.34% and a 52-week gain of 66.94% [2] Group 2 - Alnylam Pharmaceuticals, Inc. is recognized for its innovative platform in RNA interference therapeutics, with a focus on areas like cardiomyopathy, indicating potential for robust growth [3] - The company has a market capitalization of $60.083 billion, with its stock closing at $458.37 per share on September 24, 2025 [2] - Despite its potential, Alnylam Pharmaceuticals is not among the top 30 most popular stocks among hedge funds, with 58 hedge fund portfolios holding the stock at the end of Q2 2025, down from 59 in the previous quarter [4]
A Dividend Cut Just Created A 9.2% Monthly Dividend Bargain
Forbes· 2025-09-18 19:00
Core Viewpoint - Dividend cuts can present investment opportunities, as the negative news is often already priced in, leading to potential undervaluation of assets [3][7]. Group 1: Market Reactions to Dividend Cuts - Wall Street analysts and individual investors often react negatively to dividend cuts, leading to knee-jerk selling of affected funds [2][3]. - BlackRock Health Sciences Term Trust (BMEZ) experienced a dividend cut, prompting some investors to sell, but this creates opportunities for contrarian investors [3][5]. Group 2: Closed-End Funds (CEFs) Dynamics - CEFs operate differently from ETFs or mutual funds, raising a fixed pool of capital at launch, which can lead to inefficiencies in trading [4]. - When investors sell CEF shares without considering underlying assets, discounts can widen, creating buying opportunities for savvy investors [4][7]. Group 3: BMEZ Fund Characteristics - BMEZ currently yields 9.2% and trades at an 11% discount to its net asset value (NAV), indicating a potential buying opportunity [7][12]. - The fund's portfolio includes biotech and medical device companies that may benefit from a favorable regulatory environment [6][8]. Group 4: Key Holdings and Performance - Alnylam (ALNY), a top holding in BMEZ, focuses on innovative RNA interference therapies and has seen significant stock gains under previous administration policies [8][9]. - Veeva Systems (VEEV), another key holding, has also performed well historically, benefiting from a favorable mergers and acquisitions environment [9][10]. - Dexcom (DXCM), the third largest holding, produces continuous glucose monitors and has experienced substantial stock growth [11]. Group 5: Future Outlook - The current administration's policies may support the healthcare sector, particularly for companies in BMEZ's portfolio, which could lead to further growth [12].