Redosable therapeutics

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Generation Bio Announces Inducement Grant under Nasdaq Listing Rule 5635(c)(4)
Globenewswire· 2025-07-07 20:05
CAMBRIDGE, Mass., July 07, 2025 (GLOBE NEWSWIRE) -- Generation Bio Co. (Nasdaq:GBIO), a biotechnology company working to change what’s possible for people living with T cell-driven autoimmune diseases, today announced that, on July 1, 2025, the company granted equity awards to one new employee, pursuant to the company’s 2025 Inducement Stock Incentive Plan, as an inducement material to such new employee’s entering into employment with the company in accordance with Nasdaq Listing Rule 5635(c)(4). The employ ...
Generation Bio to Present at the 2025 Jefferies Global Healthcare Conference
Globenewswire· 2025-05-28 10:59
Core Insights - Generation Bio Co. is focused on developing innovative therapeutics for T cell-driven autoimmune diseases [3] - The company will present at the Jefferies Global Healthcare Conference on June 4, 2025 [1] - A live webcast of the presentation will be available on the company's investor website [2] Company Overview - Generation Bio is developing redosable therapeutics that aim to reprogram T cells in vivo to combat autoimmune diseases [3] - The company utilizes cell-targeted lipid nanoparticles (ctLNP) for selective delivery of small interfering RNA (siRNA) to T cells [3] - This approach targets historically undruggable genes associated with autoimmune diseases, potentially unlocking new treatment avenues [3]
Generation Bio Reports Recent Business Highlights and First Quarter 2025 Financial Results
Globenewswire· 2025-05-07 20:05
Core Insights - Generation Bio Co. is focused on developing innovative treatments for T cell-driven autoimmune diseases using a novel cell-targeted lipid nanoparticle (ctLNP) delivery system for siRNA [2][4] Business Highlights - The company aims to address limitations in current treatments for autoimmune diseases by targeting T cell pathology, with plans to announce its lead ctLNP-siRNA program strategy in mid-2025 [2][7] Financial Results - As of March 31, 2025, the company reported cash, cash equivalents, and marketable securities of $157.6 million, down from $185.2 million as of December 31, 2024 [8][11] - Research and development expenses for Q1 2025 were $15.4 million, compared to $14.3 million in Q1 2024 [8][13] - General and administrative expenses decreased to $8.8 million in Q1 2025 from $10.4 million in Q1 2024 [8][14] - The net loss for Q1 2025 was $14.8 million, or $0.22 per share, significantly improved from a net loss of $74.5 million, or $1.12 per share, in Q1 2024 [8][14]