Core Insights - Revvity reported stronger-than-expected performance in diagnostics and life sciences, with fourth-quarter revenue exceeding expectations [2][5][6] Financial Performance - Fourth-quarter revenue reached $772 million, reflecting 4% organic growth and approximately 2% foreign-exchange tailwind [4] - Full-year revenue totaled $2.86 billion, with 3% organic growth and a 1% FX tailwind; adjusted operating margin was 27.1%, down 120 basis points year-over-year [3] - Adjusted EPS for the full year was $5.06, up 3% year-over-year, exceeding initial guidance [3] Segment Performance - Diagnostics segment revenue was $390 million, up 7% organically, while life sciences segment revenue was $382 million, flat organically [2] - Reproductive Health and Immunodiagnostics grew mid-single digits and high single digits, respectively, with notable contributions from newborn screening and Genomics England [1] Capital Deployment - Revvity repurchased over $800 million of shares in 2025, reducing share count by 8.5 million shares [8] - Free cash flow for the fourth quarter was $162 million, bringing full-year free cash flow to $515 million, with a conversion rate of 84% [9] 2026 Guidance - Management provided an initial 2026 outlook of $2.96 billion to $2.99 billion in revenue, with expected organic growth of 2% to 3% [10] - Adjusted EPS guidance for 2026 is set at $5.35 to $5.45, assuming an 18% adjusted tax rate and approximately $95 million in net interest and other expenses [11] Strategic Initiatives - The company is focusing on software and AI initiatives, including the launch of Signals Xynthetica, aimed at accelerating drug development [13] - Revvity remains disciplined on M&A, primarily targeting software and life sciences reagents [15]

Financial Data and Key Metrics Changes - In Q4 2025, the company generated revenue of $772 million, resulting in 4% organic growth, with a full-year revenue of $2.86 billion, reflecting 3% organic growth [22][24] - Adjusted EPS for Q4 was $1.70, exceeding the high end of expectations, while full-year adjusted EPS was $5.06, representing 3% growth year-over-year [10][24] - Adjusted operating margins for Q4 were 29.7%, down 60 basis points year-over-year, and for the full year, they were 27.1%, down 120 basis points year-over-year [23][24] Business Line Data and Key Metrics Changes - The diagnostics segment saw revenue of $390 million in Q4, up 10% reported and 7% organic, while the life sciences segment generated $382 million, flat on an organic basis [26][28] - For the full year, diagnostics grew 4% organically, while life sciences grew 2% organically [26][27] - The Signals software business was flat year-over-year organically in Q4 but grew in the high teens organically for the full year [27] Market Data and Key Metrics Changes - Geographically, the company experienced flat performance in both the Americas and APAC, with double-digit growth in Europe [26] - For the full year, the Americas grew low single digits, Europe grew high single digits, and APAC declined in the low single digits [26] Company Strategy and Development Direction - The company plans to continue capital deployment through share repurchases and acquisitions, having repurchased over $800 million worth of shares in 2025 [10][11] - The acquisition of ACD/Labs is expected to contribute over $20 million in revenue in 2026, adding approximately 75 basis points to overall revenue growth [12][13] - The introduction of the AI models-as-a-service platform, Signals Xynthetica, is aimed at enhancing drug development processes [15][16] Management's Comments on Operating Environment and Future Outlook - Management expressed cautious optimism regarding the recovery of end markets, reiterating a 2%-3% organic growth outlook for 2026 [12][31] - The company noted potential upside from improved customer sentiment in pharma and biotech, as well as ongoing cost efficiency initiatives [20][22] - Management highlighted the importance of maintaining a disciplined approach to capital deployment while navigating a fluid market environment [11][20] Other Important Information - The company generated free cash flow of $162 million in Q4, resulting in 84% conversion of adjusted net income, with a full-year free cash flow of $515 million [25] - The net debt to adjusted EBITDA leverage ratio was 2.7x, with 100% of debt being fixed rate [25] Q&A Session Summary Question: Can you provide more color on the 2%-3% organic growth framework and potential upside? - Management acknowledged positive signs in end markets since September and identified multiple paths for potential upside in both revenue and EPS [39][40] Question: What is the outlook for life sciences versus diagnostics relative to the 2%-3% growth? - Management indicated that life sciences is expected to grow at low single digits, while diagnostics is also expected to grow at low single digits, with specific growth rates for sub-segments [55] Question: How is the company approaching M&A opportunities? - Management stated that any potential M&A must provide a strong strategic addition and that they have not yet identified compelling targets [58] Question: Can you elaborate on the performance within pharma biotech and order trends? - Management noted cautious optimism and consistency in order trends, with no budget flush observed but improved clarity in the policy environment [60][61] Question: What are the expectations for the diagnostics business going into 2026? - Management expressed that diagnostics could provide upside, particularly in newborn screening and immunodiagnostics, despite taking a more prudent approach to assumptions [63][64]

Fourth Quarter 2025 Earnings February 2, 2026 Safe Harbor This presentation contains "forward-looking" statements within the meaning of the Private Securities Litigation Reform Act of 1995, including but not limited to statements relating to estimates and projections of future earnings per share, cash flow and revenue growth and other financial results, developments relating to our customers and end-markets, plans concerning business development opportunities, acquisitions or divestitures. Words such as "be ...

Group 1: Market Movements - Several biotech and healthcare companies experienced notable gains in after-hours trading, driven by earnings updates, guidance announcements, and broader investor sentiment [1] - FibroBiologics, Inc. (FBLG) led with a 7.68% increase, closing at $0.41, suggesting speculative interest or technical momentum [1] - Nyxoah SA (NYXH) advanced 3.94% to $5.28 after reporting preliminary results for Q4 and full year 2025, along with revenue guidance for Q1 2026 [2] - Fortress Biotech, Inc. (FBIO) climbed 6.90% to $4.49, continuing a trend of volatility despite no new news [2] - Revvity, Inc. (RVTY) gained 4.92% to close at $109.00, with investors likely reacting to a previous collaboration announcement with Eli Lilly [3] - Option Care Health, Inc. (OPCH) rose 3.28% to $33.11 after releasing preliminary unaudited financial results for Q4 and full year 2025, along with guidance for 2026 [4] - Actinium Pharmaceuticals, Inc. (ATNM) added 3.02% to close at $1.34, reflecting investor activity in the broader biotech sector [4] - Design Therapeutics, Inc. (DSGN) gained 1.97% to $9.30, indicating continued interest despite no specific news [5] Group 2: Company-Specific Developments - FibroBiologics, Inc. (FBLG) showed a significant rise without any company-specific news, indicating potential speculative interest [1] - Nyxoah SA (NYXH) provided revenue guidance for Q1 2026, which bolstered investor confidence in its growth trajectory [2] - Revvity, Inc. (RVTY) is expanding access to predictive models through a collaboration with Eli Lilly, aimed at accelerating AI-enabled drug discovery [3] - Option Care Health, Inc. (OPCH) released preliminary financial results and guidance, contributing to its positive after-hours reaction [4]

Core Insights - Revvity, Inc. (RVTY) has announced a collaboration with Eli Lilly and Company to integrate Eli Lilly's TuneLab predictive models into the Revvity Signals platform, enhancing AI-driven drug discovery capabilities [1][8] - The partnership aims to address challenges in AI drug discovery by utilizing federated learning and secure knowledge sharing, allowing organizations to collaborate effectively [2][10] - Revvity's stock has seen a 2.7% increase since the announcement, with a 6.1% rise over the past six months, compared to the industry's 10.6% growth and the S&P 500's 14.1% increase [3] Company Developments - The collaboration reinforces RVTY's Signals Xynthetica as a key component of its AI-enabled drug discovery strategy, promoting innovation across the biotech sector [4] - Joint funding initiatives by Eli Lilly and Revvity for small- and mid-sized biotech firms aim to lower entry barriers and encourage broader adoption of the Signals ecosystem [4][10] - RVTY currently holds a market capitalization of $11.84 billion, indicating its significant presence in the market [6] Technology and Market Trends - The TuneLab models leverage advanced AI and machine learning, built on extensive research data from Eli Lilly and the biotech community, enhancing predictive accuracy through federated learning [9] - The Signals platform provides essential infrastructure for utilizing TuneLab models, facilitating data management and collaboration among research teams [11] - The AI in drug discovery market is projected to reach $7.62 billion by 2026, with a CAGR of 9.9% through 2035, driven by reduced drug discovery time and costs, and increased adoption post-COVID-19 [12] Strategic Acquisitions - Revvity has announced plans to acquire ACD/Labs, enhancing its Signals capabilities by integrating advanced analytical software for pharmaceutical and materials science applications [13]

Core Insights - Revvity, Inc. has launched Signals Xynthetica, an AI-augmented design platform aimed at enhancing molecular and materials discovery across scientific industries [2][8] - The platform operates as a Models-as-a-Service (MaaS) solution, integrating advanced in-silico design capabilities with real experimental data [2][4] - Early access to Signals Xynthetica is expected in the first half of 2026, with pre-registration already underway [3][8] Product Features - Signals Xynthetica addresses the disconnect between computational models and experimental workflows, aiming to unify de novo generation, property prediction, and multi-objective optimization [4] - The platform is designed to accelerate discovery while maintaining scientific rigor, adapting to new data and benchmarking against real-world results [4][5] - Revvity emphasizes that the initiative serves as an operational backbone for predictive science, aligning AI predictions with laboratory realities [5] Market Position and Trends - Following the announcement, RVTY shares have remained relatively flat, gaining 1.4% over the past six months compared to the industry’s 6.2% growth and the S&P 500's 15.3% increase [6] - The introduction of Signals Xynthetica is expected to enhance Revvity's prospects as demand for predictive tools integrated with empirical workflows grows [7] Strategic Vision - Revvity is evolving from a provider of discrete scientific tools to a platform-centric technology partner, leveraging AI and cloud delivery to accelerate discovery and standardize workflows [14] - The acquisition of ACD/Labs is expected to strengthen Revvity's strategy by incorporating specialized analytical and molecular design tools into the Signals ecosystem [15]