Core Insights - Zoetis has received a positive opinion from the European Medicines Agency's Committee for Veterinary Medicinal Products for its monoclonal antibody therapy, Portela, aimed at alleviating osteoarthritis pain in cats [1][5] - The company anticipates a final decision from the European regulatory body in Q4 2025, with potential commercialization in 2026 [2] Product Development - Portela is designed to provide up to three months of pain relief with a single injection, addressing a significant unmet need in feline care where treatment options for chronic pain are limited [3][5] - The therapy has shown favorable safety and efficacy data, being well-tolerated even in cats with early-stage kidney disease [3] Market Positioning - The approval of Portela would mark a significant advancement in veterinary medicine, as it would be the first long-acting anti-NGF monoclonal antibody therapy for cats [3][9] - Portela is expected to complement Zoetis' existing anti-NGF therapy, Solensia, providing veterinarians and pet owners with both monthly and quarterly treatment options for osteoarthritis pain [9][10] Industry Context - Osteoarthritis affects up to 40% of cats, with only 18% formally diagnosed, highlighting the importance of early identification and treatment [8] - The introduction of Portela aligns with Zoetis' strategy of disruptive innovation in companion animal health, potentially deepening its market penetration in the growing feline osteoarthritis segment [10]