Core Insights - OXB has been recognized as a Champion in the 'Cell & Gene Therapy' category at the 2025 CDMO Leadership Awards Europe, reflecting its high performance based on feedback from biopharmaceutical professionals [1][2] - This recognition highlights OXB's excellence in quality, innovation, and service, coinciding with strong commercial momentum driven by increased demand for its CDMO services [2][3] Company Overview - OXB is a global contract development and manufacturing organization (CDMO) specializing in cell and gene therapy, with a mission to enable clients to deliver life-changing therapies [4][5] - The company has 30 years of experience in viral vectors, collaborating with innovative pharmaceutical and biotechnology companies to provide expertise in various viral vector types [5][6] - OXB's capabilities range from early-stage development to commercialization, supported by robust quality-assurance systems and regulatory expertise [5][6] Technological Capabilities - OXB offers a wide range of technologies for viral vector manufacturing, including a 4th generation lentiviral vector system (TetraVecta™) and a dual-plasmid system for AAV production [6] - The company utilizes advanced processes such as suspension and perfusion processes with process enhancers and stable producer and packaging cell lines [6] Industry Recognition - The CDMO Leadership Awards recognize organizations that excel in quality, capabilities, expertise, reliability, compatibility, and service, based on direct feedback from industry professionals [8]

Core Insights - OXB, a leading CDMO in cell and gene therapy, will participate in several upcoming investor conferences and events, showcasing its commitment to engaging with investors [2][3]. Conferences and Events - OXB will attend the Stifel Healthcare Conference in New York and the Jefferies Global Healthcare Conference in London [3]. - A virtual event, the Jefferies C-Suite "Back to School" Fireside Chat, is scheduled for November 4, 2025, with live webcasts available on OXB's website [3][4]. - Additional financial events can be found on the company's investor calendar [4]. Company Overview - OXB has 30 years of experience in viral vectors, essential for most cell and gene therapies, and collaborates with innovative pharmaceutical and biotechnology companies [7]. - The company offers a range of technologies for viral vector manufacturing, including the TetraVecta™ system for lentiviral vector production and advanced AAV production methods [9]. - OXB is a FTSE250 and FTSE4Good constituent, with facilities in the UK, France, and the US, emphasizing its global presence and capabilities [9].

Core Insights - OXB has acquired a state-of-the-art viral vector manufacturing facility in North Carolina from RTP Operating, LLC, enhancing its capabilities in the cell and gene therapy sector [1][8] - The acquisition aligns with OXB's strategic initiatives to expand its US commercial capabilities and meet growing client demand [4][7] Group 1: Acquisition Details - The facility is FDA approved and adds commercial-scale GMP capacity, enabling OXB to support late-stage programs and commercial launches for clients worldwide, particularly in the adeno-associated virus (AAV) field [2][9] - OXB paid $4.5 million (£3.4 million) for the assets, funded by existing cash, with integration planning expected to be operational by Q1 2026 [5][6] Group 2: Operational Enhancements - The North Carolina site includes two operational GMP drug substance suites, a dedicated fill-finish suite, and on-site QC labs, complementing OXB's existing global network [3][11] - The company plans to invest in the new facility, including hiring additional operational staff to enhance US fill-finish capacity and expedite client onboarding [6][8] Group 3: Financial Outlook - The acquisition is expected to support OXB's long-term top-line growth and maintain existing financial guidance, with an anticipated single-digit gain in 2025 [5][7] - OXB aims to achieve EBITDA profitability from FY 2025 and strengthen its competitive position in the global viral vector market [7][9]

Core Viewpoint - OXB has shown strong commercial momentum and operational progress in 2025, continuing to provide viral vector manufacturing services to a diverse client base, and remains on track to meet its financial outlook for the year ended December 31, 2024 [2][3]. Group 1: Company Performance - OXB has delivered strong operational performance in the first half of 2025, reflecting disciplined execution across global sites and sustained commercial momentum [3]. - The company reiterates its financial guidance and remains focused on supporting clients at all development stages, expressing confidence in its near and medium-term targets [3]. Group 2: Company Background - OXB is a pioneer in cell and gene therapy with 30 years of experience in viral vectors, collaborating with innovative pharmaceutical and biotechnology companies [5]. - The company provides expertise in various viral vector types, including lentivirus, adeno-associated virus (AAV), and adenovirus, supporting capabilities from early-stage development to commercialization [5]. Group 3: Technological Capabilities - OXB offers unique technologies for viral vector manufacturing, including a 4th generation lentiviral vector system (TetraVecta™) and a dual-plasmid system for AAV production [6]. - The company utilizes advanced processes such as suspension and perfusion with process enhancers, along with stable producer and packaging cell lines [6]. Group 4: Corporate Information - OXB is headquartered in Oxford, UK, with development and manufacturing facilities in Oxfordshire, UK, Lyon and Strasbourg, France, and Bedford, MA, US [7].

Core Insights - OXB has launched the Innovation and Technology Excellence Board (ITEB) to enhance its capabilities in cell and gene therapy and maintain its leadership position in the market [1][2][3] Company Overview - OXB is a global contract development and manufacturing organization (CDMO) specializing in cell and gene therapy, with a mission to enable clients to deliver transformative therapies to patients [15][16] - The company has 30 years of experience in viral vectors, collaborating with innovative pharmaceutical and biotechnology companies [16] Strategic Initiatives - The ITEB will provide strategic insights to identify opportunities for scientific enhancement and innovation, ensuring OXB remains at the forefront of technology development [2][3] - The board aims to improve treatment development, manufacturing, and delivery processes, focusing on practical advances for clients and better patient outcomes [3] Leadership and Expertise - The ITEB is chaired by Prof. Dame Kay Davies, a respected figure in human genetics, with founding members including leading experts in molecular biology, gene therapy, and biopharmaceuticals [3][4][5][6][7] - Dr. Frank Mathias, CEO of OXB, emphasizes the importance of the ITEB in adapting to scientific and technological changes to better serve clients [3][10] Technological Capabilities - OXB offers unique technologies for viral vector manufacturing, including a 4th generation lentiviral vector system and advanced AAV production methods [17] - The company supports its capabilities with robust quality-assurance systems and regulatory expertise, facilitating a range of services from early-stage development to commercialization [16]