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10x Genomics and A*STAR Genome Institute of Singapore Launch TISHUMAP Study to Advance AI-Driven Drug Target Discovery
Prnewswireยท 2025-07-17 13:00
Core Insights - 10x Genomics and A*STAR Genome Institute of Singapore have launched a collaboration for the TISHUMAP project aimed at drug target discovery and precision medicine for cancer and inflammatory diseases [1][2][3] Group 1: Project Overview - The TISHUMAP project will analyze up to 2,500 formalin-fixed paraffin-embedded (FFPE) clinical tissue samples from various cancers, including gastric, liver, and colorectal cancers [2] - The project utilizes 10x Genomics' Xenium platform, which allows for visualization of gene activity within individual cells in intact tissues, providing a detailed molecular-level map of cellular interactions [2][4] - The collaboration aims to develop new diagnostics and personalized treatment plans by identifying novel biomarkers and drug targets through advanced AI analysis [2][3] Group 2: Collaboration Details - A*STAR GIS and 10x Genomics will work on both data generation and analysis, creating tailored gene panels and intelligent software pipelines for managing large datasets [3] - The partnership focuses on streamlining lab workflows and developing advanced tools for sample preparation, imaging, and spatial biology data analysis [3] Group 3: Company Background - 10x Genomics is a life science technology company that provides integrated research solutions for single cell and spatial biology, contributing to breakthroughs in various fields including oncology and immunology [5] - A*STAR GIS is part of Singapore's Agency for Science, Technology and Research, focusing on genomic sciences to improve human health and societal impact [6][7]