Core Insights - Avantor, Inc. reported a third-quarter 2025 adjusted EPS of 22 cents, a decline of 15.4% year-over-year, missing the Zacks Consensus Estimate by 4.4% [1] - Revenues for the quarter were $1.62 billion, down 5.3% year-over-year, also missing the Zacks Consensus Estimate by 1.6% [2] - The company has revised its 2025 guidance, projecting organic revenue decline of 3.5% to 2.5% and adjusted EPS in the range of 88 to 92 cents [10][11] Revenue Details - Avantor's revenues were $1.62 billion, reflecting a 5.3% decrease year-over-year, with a 4.7% organic sales decline [2] - Foreign currency translation positively impacted revenues by 2.2%, while M&A negatively impacted by 2.8% [2] Segmental Analysis - The Laboratory Solutions segment reported net sales of $1.09 billion, down 6.4% year-over-year, with organic sales decreasing by 4.9% [3] - Bioscience Production's net sales were $527.3 million, a decrease of 2.9%, with organic sales down 4.3% [5] Margin Analysis - Gross profit declined 6.7% year-over-year to $526.5 million, with a gross margin contraction of 50 basis points to 32.4% [7] - Adjusted operating profit totaled $237.3 million, down 13.7% from the prior year, with an adjusted operating margin of 14.6% [7] Financial Position - At the end of Q3 2025, Avantor had cash and cash equivalents of $251.9 million, down from $449.4 million at the end of Q2 [9] - Total debt decreased to $3.86 billion from $4.24 billion at the end of Q2 [9] Guidance - The company expects organic revenue growth to decline by 3.5% to 2.5%, revising previous guidance of negative 2% to flat [10] - Adjusted EPS guidance was lowered to 88 to 92 cents from a previous range of 94 to 98 cents [11] Strategic Initiatives - Avantor is focusing on a multi-year cost-transformation program targeting $400 million in run-rate savings by the end of 2027 [14] - The company is enhancing its product and innovation pipeline, particularly in bioprocessing, and has formed strategic collaborations to expand its market presence [13]