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Tempus Ai,Inc.(TEM) - 2024 Q3 - Earnings Call Transcript

Financial Data and Key Metrics - Revenue growth of 33% YoY, reaching 180.9millioninQ32024[6]Genomicsunitgrowthacceleratedto23.9180.9 million in Q3 2024 [6] - Genomics unit growth accelerated to 23.9% YoY, with overall business growth around 20% [6] - Data and Services revenue grew 64.4% YoY, driven by data licensing business growth of 86.6% [7] - Adjusted EBITDA improved to negative 21.8 million, a 14.4millionYoYimprovement[7]AcquisitionofAmbryGeneticsfor14.4 million YoY improvement [7] - Acquisition of Ambry Genetics for 600 million (375millionincash,375 million in cash, 225 million in equity) at 1.9x revenue and 15x EBITDA [11] Business Line Performance - Genomics business delivered 69,000 tests in Q3, up from 66,500 in Q2, driven by core assays (xT, xR, xF) [28] - Data licensing business growth of 86.6% YoY, with total contract value (TCV) remaining above 900million[24][26]AmbryGeneticsacquisitionexpectedtoaccelerateEBITDAandcashflowbreakeven,withAmbrygrowingatover25900 million [24][26] - Ambry Genetics acquisition expected to accelerate EBITDA and cash flow breakeven, with Ambry growing at over 25% and generating significant EBITDA [9][10] Market Performance - Ambry Genetics is a leader in hereditary screening, with 95% of its volume in-network and strong payer relationships [45] - Tempus' Genomics business is primarily out-of-network, with recent progress in securing in-network contracts with Blue Shield of Illinois, Blue Shield of California, and Avalon [40] - Combined Tempus and Ambry business expected to generate 1 billion in revenue and grow at 23%-25% annually [44] Strategic Direction and Industry Competition - Ambry acquisition aligns with Tempus' strategy to offer comprehensive genomic profiling, from hereditary screening to therapy selection and minimal residual disease (MRD) monitoring [15][16] - Tempus aims to be a one-stop shop for oncologists, offering end-to-end solutions, similar to Amazon's approach in e-commerce [15] - The company is focused on leveraging AI in diagnostics and expanding its data business, with tools that make data usable for biotechs and pharmaceutical companies [25][50] Management Commentary on Operating Environment and Future Outlook - Tempus is on track to achieve adjusted EBITDA and cash flow breakeven, with Ambry acquisition accelerating this timeline [7][10] - Data business growth is expected to moderate from 87% YoY, with a focus on sustainable long-term growth in the 25% range [24][50] - Reimbursement for MRD testing remains a key gating factor, with progress expected in the coming years [20] Other Important Information - Tempus added 60 new sales reps in Q3, with productivity expected to improve over the next 6-9 months [30][31] - The company is exploring reimbursement pathways for AI-based diagnostic tools, which could unlock significant future revenue potential [59] Q&A Summary Question: Sustainability of Ambry's 25% growth rate and integration plans [13] - Ambry's growth is stable, with no signs of systemic slowdown, and the business is synergistic with Tempus' existing operations [17][18] - Integration will be gradual, with Ambry operating independently in the near term, but synergies expected in data business and payer relationships [45] Question: Data business growth and TCV trends [21][22] - Data business remains strong, with TCV above $900 million and Q4 historically being the largest quarter for data licensing [26] - Growth rates are expected to moderate, with a focus on sustainable long-term growth [24] Question: Sales force productivity and impact on growth [30][31] - Sales force productivity is improving, with reps expected to reach full efficiency in 6-9 months [31] - The impact on growth is minimal, with fluctuations in test volumes not significantly affecting financial health [33] Question: Ambry's revenue contribution and synergies [36][42] - Majority of Ambry's revenue is external, with minimal overlap with Tempus' existing business [37] - Synergies include leveraging Tempus' data business and Ambry's in-network payer relationships [45] Question: Reimbursement trends and ASP improvements [39][40] - Progress with commercial payers led to incremental ASP improvements, with ADLT status expected to drive further gains in 2025 [40] Question: Data purchasing environment and new customer trends [53] - Data business continues to see strong interest, with large wins like BioNTech, but overall market tailwinds have subsided [54] - Tempus expects a potential rebound in data purchasing as capital becomes more freely available in 2025 or 2026 [55] Question: AI applications and monetization pathways [56] - Collaboration with Northwestern Medicine on ECG-AF algorithm highlights potential for AI applications in healthcare [57] - Reimbursement for algorithmic diagnostics remains a key challenge, with significant revenue potential once payment pathways are established [59] Question: Ambry's impact on health system relationships [61] - Ambry's in-network payer relationships and genetic counselor focus complement Tempus' oncologist-driven business, strengthening overall platform [62][63] Question: Profitability and investment balance post-Ambry acquisition [65] - Tempus is now on an annualized EBITDA and cash flow positive basis, with a focus on sustaining growth rather than maximizing short-term profitability [66][67] Question: Reimbursement trends in psychiatric pharmacogenomics [69] - Tempus' neuropsych business is small, with minimal impact from reimbursement disruptions in the broader market [69] Question: Billing and value proposition of Tempus' CGP test [70] - Tempus follows established reimbursement pathways, with rates set by CMS and local MACs, and expects further ASP improvements with ADLT status [71][72]