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scPharmaceuticals (SCPH) - 2024 Q3 - Earnings Call Transcript

Financial Data and Key Metrics Changes - The company generated net revenue of 10millioninQ32024,representinga2410 million in Q3 2024, representing a 24% increase from Q2 2024 [8] - The gross net discount for FUROSCIX was approximately 15.7%, exceeding the guided range of 10% to 15% [9] - The net loss for Q3 2024 was 35.1 million, compared to 15.6millioninQ32023,primarilyduetoonetimecharges[27][28]BusinessLineDataandKeyMetricsChangesApproximately3,100uniquehealthcareprovidersprescribedFUROSCIX,a1315.6 million in Q3 2023, primarily due to one-time charges [27][28] Business Line Data and Key Metrics Changes - Approximately 3,100 unique healthcare providers prescribed FUROSCIX, a 13% increase compared to Q2 2024 [18] - The company filled approximately 10,800 doses of FUROSCIX, a 16% increase from the previous quarter, with the average number of doses per prescription rising to 6.8 [19] - The acceptance of the sNDA filing by the FDA for expanding FUROSCIX's indication to include CKD patients was a significant achievement [12] Market Data and Key Metrics Changes - The company anticipates that the GTN discount will increase to 35% by the end of 2025 due to the Medicare Part D redesign [9] - The company ended Q3 2024 with 91.5 million in cash and cash equivalents, up from 76millionattheendof2023[28]CompanyStrategyandDevelopmentDirectionThecompanyisfocusedonexpandingFUROSCIXsindicationstocoverallheartfailurepatients,includingClassIVpatients,whichrepresentasignificantportionofhospitalizations[10]ThecompanyispreparingforapotentiallaunchofFUROSCIXforCKD,withaPDUFAdatesetforMarch6,2025[14]ThetransformativefinancingcompletedinAugust2024addedapproximately76 million at the end of 2023 [28] Company Strategy and Development Direction - The company is focused on expanding FUROSCIX's indications to cover all heart failure patients, including Class IV patients, which represent a significant portion of hospitalizations [10] - The company is preparing for a potential launch of FUROSCIX for CKD, with a PDUFA date set for March 6, 2025 [14] - The transformative financing completed in August 2024 added approximately 75 million to the balance sheet, supporting projected cash flow through expected profitability [16] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about growth driven by sales force expansion and indication expansion for FUROSCIX [8] - The management noted that the fourth quarter is expected to be the biggest opportunity of the year due to increased hospital admissions related to fluid overload during the holiday season [34] - Management highlighted the positive reception from nephrologists regarding FUROSCIX, indicating a strong potential for the CKD market [42] Other Important Information - The company is working on a low-volume Autoinjector, which demonstrated promising results in a PK/PD bridging study [15] - The new FUROSCIX direct patient services hub has improved the prescribing process, receiving positive feedback from healthcare providers [20] Q&A Session Summary Question: What do you think the doses per prescription could look like for FUROSCIX and CKD relative to heart failure? - Management indicated that doses for CKD would be similar to Class II and Class III heart failure patients, around 6.0 to 6.5 [31] Question: What do you think the rate of on-body diffuser versus autoinjector could shake out to in the long-term? - Management projected that over 90% of treatments would be in the autoinjector format, with some patients likely to remain on the current system [32] Question: Is there any expected seasonality that we could see in Q4? - Management confirmed that Q4 is expected to have the highest sales due to increased hospital admissions related to fluid overload during the holidays [34] Question: What percentage of prescriptions do you think will be Class IV as you exit the year? - Management noted that Class IV patients currently represent about 10% of prescriptions, with expectations for growth [38] Question: Can you comment on how the initial nephrology detailing is going? - Management reported positive reception from nephrologists, with many expressing interest in prescribing FUROSCIX [42] Question: What led to a slower end to the quarter than expected? - Management attributed the slowdown to coverage gap rebates affecting fill rates, despite continued growth in script writing [45][46] Question: What was the conversion rate in the third quarter? - The fill rate for prescriptions was 53%, an increase from 48% in Q2 [48] Question: How do you see the conversion rate going into next year with the Part D redesign? - Management projected a fill rate of 65% for next year, benefiting from the redesign and increased affordability for patients [55]