Mind Medicine (MindMed) (MNMD) - 2025 Q2 - Earnings Call Presentation

Financial Highlights - MindMed reported cash, cash equivalents, and investments of $237.9 million as of June 30, 2025[11], which is expected to fund operations into 2027 and at least 12 months beyond the first Phase 3 topline data readout in GAD[12, 15] - The company has a credit facility of up to $120 million, with $42 million outstanding as of June 30, 2025[63] - Operating expenses for the second quarter of 2025 totaled $40.9 million, including $29.8 million for R&D and $11.1 million for G&A[63, 66] - MindMed completed a $250 million equity investment[15, 63] Clinical Development - MM120 - The company's lead clinical program, MM120 ODT, is in three Phase 3 studies targeting Generalized Anxiety Disorder (GAD) and Major Depressive Disorder (MDD)[11] - Three Phase 3 topline readouts are anticipated in 2026: one in the first half for GAD (MM120-300) and two in the second half for GAD (MM120-301) and MDD (MM120-310)[14, 64] - MM120 Phase 2b trial demonstrated a 21.9-point improvement on the HAM-A at Week 12 (p=0.003) and a 48% remission rate in participants at Week 12[34] - MM120 Phase 2b also showed a 18.7-point improvement in MADRS score at Week 12, with a 6.4-point improvement over placebo (p<0.01)[38] Market Opportunity - 26 million U S adults live with GAD and 41 million U S adults live with MDD[20] - Approximately 50% of GAD patients fail first-line pharmacological treatments[20] - Approximately 2/3 of MDD patients do not achieve remission after first-line therapy, and 30% fail by 2+ lines of therapy[20] - Surveyed providers indicated that 62% of all psychiatric providers and 78% of interventional psychiatric providers believe the availability of psychedelics for GAD and MDD will change their approach to treatment[24]