2025-08-11 01:21Summary of Haishike's Conference Call Company Overview - Haishike was established in 2000 and is headquartered in Chengdu, with over 5,300 employees. The company initially focused on specialized fields such as parenteral nutrition, liver disease, and anti-infection, and is now transitioning towards innovation and international development [9] Industry and Product Pipeline - Haishike has a robust domestic commercialization pipeline, including already launched products such as Remifentanil (环泊芬), 21,542, 16,149, and DPP-4, along with the anticipated launch of 22,542 in 2025. The company expects a revenue growth of 15%-20% in 2025 [2][3] - Remifentanil is projected to achieve sales of 1.6-1.7 billion CNY in 2025, with a sales volume of 25 million units, solidifying its position as the leader in the domestic intravenous anesthetics market [2][4] - The innovative drug 21,542, an opioid analgesic with lower addiction potential, is expected to reach peak sales of 4 billion CNY domestically. The new generation analgesic 16,149, launched in May 2024, is projected to achieve peak sales of 1.5 billion CNY [2][6] - DPP-4, a long-acting hypoglycemic agent, has been approved in China and is entering the volume release phase under medical insurance [2][6] Market Performance and Competitive Advantages - Remifentanil has significant clinical advantages, including deeper anesthesia and higher safety, with a market share leading position. A simple renewal negotiation for medical insurance is expected by the end of the year, with a potential price reduction of less than 10% [5][11] - 21,542 is the only white prescription opioid, making it easier for doctors to prescribe. It is expected to replace traditional opioids like Dezocine, which is gradually exiting medical insurance [12] - 16,149 is positioned to replace Pregabalin in chronic pain treatment, with expected peak sales of 1-1.5 billion CNY [14] Research and Development - Haishike's R&D investment has been increasing since 2018, with a significant acceleration in 2022. The company has a rich pipeline of innovative drugs, including four major launched products and several in late-stage clinical trials [10] - Products with international market potential include PDE34 and PDE4B for COPD and interstitial pneumonia, and an oral interleukin-23 receptor peptide for autoimmune diseases, which are expected to yield data by the end of the year [7] Financial Projections and Valuation - The projected net profit for Haishike from 2025 to 2027 is 570 million, 780 million, and 910 million CNY, respectively, with corresponding price-to-earnings (PE) ratios of 110x, 81x, and 70x [8] - The target market capitalization is set at 71 billion CNY, maintaining a buy rating [8][26] Additional Insights - The textile drug market is expected to stabilize in profit growth, with projected profits of 574 million CNY this year, nearing 800 million CNY next year [25] - The competitive landscape for COPD treatments in China includes several players, with Haishike's PDE34 expected to read out phase II data by the end of the year [24] This summary encapsulates the key points from Haishike's conference call, highlighting the company's strategic positioning, product pipeline, market performance, and financial outlook.