Jazz Pharmaceuticals(JAZZ) - 2023 Q3 - Earnings Call Presentation

BRAF Mutant Mutant RAS or RTK CLASS 1 CLASS 2 CLASS 3 Driven B-RAF B-RAF Mutated B-RAF Mutated mEGFR / mRTK V600E Driven Dimer Driven RAS Driven mRAS RAS RAS RAS B-RAF B-RAF C-RAF / WT C-RAF / B-RAF C-RAF / C-RAF V600E D594X B-RAF A-RAF A-RAF G469X A-RAF MEK MEK MEK MEK Growth Inhibition Growth Inhibition Growth Inhibition Cell Growth Growth Inhibition █ 1st Gen. B-RAF V600E Inhibitor ● Pan-RAF Inhibitor JZP815 Examine antitumor activities across patient mutation subsets | --- | --- | |--------------------- ...