Fulcrum Therapeutics(FULC) - 2023 Q2 - Earnings Call Presentation

• Muscle fat infiltration (MFI): Measure of muscle health motion Tissue infiltration contributes to the loss of function by altering biomechanical properties 0% • MFF is an indicator of FSHD-affected muscles with a strong correlation to clinical function / disability Illustrative Normal-Appearing Intermediate End-stage Arjomand J, et al. Facioscapulohumeral muscular dystrophy (FSHD) voice of the patient report. Published November 5, 2020. Accessed March 1, 2021 8 10 p38α/β ON Losmapimod, a Highly Selective ...