Financial Data and Key Metrics Changes - In 2023, the company reported total revenues of approximately 15.4billion,adjustedEBITDAofapproximately5.1 billion, and free cash flow of approximately 2.4billion[36][46][62]−Theadjustedgrossmarginforthefullyearwasat59.1450 million to 550million[3][52]BusinessLineDataandKeyMetricsChanges−TheGreaterChinasegmentdelivered22.5 billion in free cash flow in 2024 before any divestiture costs and taxes [53] - Management highlighted the importance of finding impactful assets that can drive long-term revenue streams [72] Other Important Information - The company completed 250millioninsharerepurchasesearlierintheyearandhasanadditional1 billion share repurchase authorization [28] - The anticipated driver for adjusted EBITDA includes contributions from new product launches and revenue growth, with an estimated impact from remaining divestitures [53][56] Q&A Session Summary Question: Follow-up on business development strategy - Management indicated that finding impactful assets is challenging, but building a commercial structure around them is easier if the asset is impactful [72] Question: Thoughts on the Eye Care franchise and commercial launch of Ryzumvi - Management noted that the DTC campaign for Tyrvaya has shown an 18% increase in prescriptions, and they are optimistic about the upcoming launch of Ryzumvi [112] Question: Insights on the FTC examination regarding PBMs and wholesaler practices - Management observed stabilization in pricing and emphasized the industry's shift towards quality and availability rather than just cost [120] Question: Differentiation of Selatogrel and Cenerimod - Management highlighted that Selatogrel targets a critical time in heart attack treatment where no current treatment exists, while Cenerimod shows strong Phase 2 data and fast track designation [104][105] Question: Philosophical approach to business development - Management stated that they will consider a wide range of opportunities, including licensing and partnerships, while focusing on building a strong portfolio [124]