PepGen (PEPG) Investor Presentation - Slideshow

NT T NT T NT T 0 100 200 300 400 Pcolce/Rplp0 (normalized to control) Untreated DM1 control 2 wks 12 wks 24 wks Protocol: PGN-EDODM1 was administered once intravenously (IV) to HSALR mice at 30 mg/kg; quadriceps muscle harvested 2, 12 or 24 weeks postadministration; graph plotted as mean ± SD; n=7 for 0 timepoint, 8 for 2- and 12-week timepoints; 5 for 24-week timepoint. Transcript levels measured by qPCR and normalized to Rplp0. NT = not treated. NHP: IND-ENABLING STUDIES DOSED THROUGH 90 MG/KG, RESULTS SU ...