
Financial Data and Key Metrics Changes - The company reported a net loss of $14.0 million for 2023, a decrease from a net loss of $25.7 million in 2022, indicating improved financial performance [16] - Revenue increased to $1.8 million in 2023 from $1.5 million in 2022, primarily driven by the Eagan operating segment [30] - Cash and cash equivalents decreased to $8.7 million as of December 31, 2023, down from $22.1 million in the previous year [30] Business Line Data and Key Metrics Changes - The Eagan operating segment contributed $1.135 million in revenue for 2023, up from $1.064 million in 2022, while the Pittsburgh segment increased to $493,000 from $359,000 [30] - Operating expenses decreased to $3.7 million in 2023 from $3.8 million in 2022, mainly due to lower research and development expenses [15] Market Data and Key Metrics Changes - The company highlighted its unique position in the artificial intelligence drug discovery market, leveraging a proprietary biobank of over 150,000 tumor samples and extensive drug response data [34] - The injectable drug market is projected to grow from $6 billion to $10 billion by 2034, indicating significant market opportunities for the company [37] Company Strategy and Development Direction - The company has restructured and repositioned itself over the past year, focusing on accelerating growth through its PEDAL platform and biobank capabilities [3][4] - The strategic vision includes leveraging proprietary data to aid drug development partners and enhance clinical trial designs [24][25] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about the progress made since implementing the new strategic vision, emphasizing the importance of partnerships and collaborations in driving future growth [32] - The company aims to mitigate risks in drug development by providing accurate predictions of tumor responses, which could significantly enhance the success rates of drug candidates [19][20] Other Important Information - The company has engaged in collaborations with various organizations, including Cvergenx and FluGen, to develop innovative solutions in drug discovery and vaccine development [26][37] - A proposal was submitted to the RK Mellon Foundation to enrich data sets necessary for modeling, which is crucial for future collaborations and drug development efforts [25] Q&A Session Summary Question: What is the company's outlook on drug development costs and risks? - The company noted that drug development is inherently expensive and risky, particularly in oncology, with only a small fraction of drugs selected for clinical trials ultimately receiving approval [43] Question: How does the company plan to utilize its data for clinical utility? - The company is exploring the possibility of reevaluating data to develop biomarker leads and new predictive models for various cancer types, as well as for drug repurposing and combinations [44]