Financial Data and Key Metrics Changes - Revenues for Q3 2025 were $108.4 million, an 8% increase from $100.6 million in Q3 2024 [7] - For the nine months ending September 2025, revenues reached $325.1 million, a 13% increase over $288 million in the same period last year [7] - Expenses for Q3 2025 were $101.4 million, also up 8% from $93.7 million in Q3 2024 [8] - Net income for Q3 2025 was $4.9 million, a 2% increase from $4.8 million in Q3 2024 [9] - Diluted earnings per share remained flat at $0.20 for Q3 2025, compared to the same period last year [9] Business Line Data and Key Metrics Changes - The fair value portfolio increased to $3.6 billion, yielding 11.4% net of losses [7] - Origination volumes for Q3 2025 were $391.1 million, with a total of $1.275 billion for the nine months, a 4% increase year-over-year [13] - The percentage of the portfolio from troubled 2022 and 2023 vintages is now below 30% [19] Market Data and Key Metrics Changes - The unemployment rate stood at 4.3% as of August 2025, with expectations to rise to 4.5% in 2026 [22] - The company noted increased competition from banks and credit unions, which may pressure growth [25] Company Strategy and Development Direction - The company is focusing on organic growth by adding new dealers and improving capture rates, which have increased from the high fours to over 6% [15] - A specific focus on large dealer groups has led to their originations comprising 31% of total originations, up from 17% two years ago [16] - The company aims to maintain APRs while improving margins and cutting expenses [27] Management's Comments on Operating Environment and Future Outlook - Management expressed a positive outlook for 2025, anticipating it to be the second-best year in the company's history despite modest growth [13][14] - The company is not overly concerned about a slight increase in unemployment, viewing it as a manageable risk [28] - Management highlighted that the performance of newer vintages (2024 and 2025) is showing improvement, indicating a positive trend in credit performance [19][20] Other Important Information - The company successfully completed a securitization despite market challenges, indicating stability in the market [6][25] - The total debt increased by 11% to $3.4 billion, while the fair value portfolio grew by 16%, showing improved balance sheet management [10][11] Q&A Session Summary - No specific questions or answers were provided in the transcript, as the call concluded without a Q&A segment [31]

Financial Data and Key Metrics Changes - In Q3 2025, the company reported a profit of $0.65 per diluted share, generating approximately $1.5 billion in free cash flow before working capital adjustments [21][22] - Operating cash flow reached $3.2 billion, exceeding last year's Q3 performance despite lower WTI prices [7][21] - The company repaid $1.3 billion of debt in the quarter, reducing the total principal debt balance to $20.8 billion [22][27] Business Line Data and Key Metrics Changes - The oil and gas business produced approximately 1.47 million barrels of oil equivalent (BOE) per day, exceeding guidance, with the Permian Basin contributing 800,000 BOE per day, marking the highest quarterly production in Oxy's history [9][23] - The midstream and marketing segment generated positive adjusted earnings of $153 million, surpassing guidance due to strategic gas marketing [23][24] Market Data and Key Metrics Changes - The company shifted its oil and gas production from 50% domestic to 83% domestic, reducing geopolitical risk [5] - The Gulf of Mexico assets achieved the highest uptime in operating history, benefiting from favorable weather conditions [9] Company Strategy and Development Direction - The sale of OxyChem is a pivotal step in the company's transformation, aimed at strengthening the balance sheet and enhancing shareholder returns [4][6] - The company plans to focus capital on Permian unconventional assets and Gulf of Mexico water floods, with an emphasis on low-decline enhanced oil recovery projects [6][20] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the company's ability to navigate changing market conditions with a focus on operational efficiency and cost management [19][20] - The company is targeting a $55-$60 WTI plan for 2026, with flexibility to adapt to market conditions while maintaining operational performance [20][21] Other Important Information - The company has a development runway of over 30 years, with a focus on high-return, short-cycle assets [5] - The OxyChem transaction is expected to lower annual interest expenses by more than $350 million and improve credit metrics [27] Q&A Session Summary Question: Can you clarify the capital spending outlook for next year? - Management indicated that capital spending could range between $6.3 billion and $6.7 billion, with increased investment in Gulf of Mexico water flood projects and Oman [33][34] Question: What is the sustaining capital break-even for the portfolio? - Management stated that annual program break-evens are all less than $40, with ongoing improvements in resource expansion and cost efficiency [38][40] Question: How will the water flood projects impact productive capacity in the Gulf of Mexico? - The water flood projects are expected to improve recoveries by nearly 150 million BOE and significantly reduce decline rates over time [46][47] Question: What are the plans for share repurchases and addressing legacy liabilities? - Management plans to prioritize debt reduction before opportunistically repurchasing shares, with legacy liabilities having minimal impact on operations [55][56]

Virtual KOL Investor Event November 11, 2025 © 2025 Esperion Therapeutics, Inc. All rights reserved. Forward-looking Statements & Disclosures Breaking the Statin Intolerance Barrier: Closing the Care Gap in Cardiovascular Health This investor presentation contains forward-looking statements that are made pursuant to the safe harbor provisions of the federal securities laws, including statements regarding marketing strategy and commercialization plans, current and planned operational expenses, expected profi ...

Summary of IQVIA Holdings Conference Call Company Overview - **Company**: IQVIA Holdings (NYSE:IQV) - **Industry**: Healthcare, specifically focused on clinical research and data analytics for the pharmaceutical sector Key Financial Highlights - **Third-Quarter Results**: Reported financial numbers at the high end of guidance, with over 5% revenue growth expected for the year [2][30] - **New Business Bookings**: $2.6 billion in new business booked in the clinical segment, with a book-to-bill ratio of 1.15 [2][3] - **Request for Proposals (RFPs)**: Increased by 20% year-over-year, indicating strong demand [2][14] Industry Dynamics - **Market Recovery**: The period of uncertainty in the pharmaceutical industry is lifting, with decision timelines returning to normal [3][9] - **Impact of COVID-19**: The industry experienced overspending and overinvestment during the pandemic, leading to a subsequent decline in capital availability for emerging biotech [5][6] - **Cancellations of Clinical Trials**: Elevated cancellations due to economic reasons and uncertainty have largely subsided [6][7] Macro Environment - **Regulatory Changes**: The Inflation Reduction Act (IRA) and other macro events created uncertainty, affecting large pharma's investment decisions [6][9] - **FDA Changes**: Leadership changes and unclear policies at the FDA contributed to a difficult environment for investment [7][9] Business Segments and Trends - **R&D Spend Growth**: Long-term growth forecast for the top 15 pharma companies is around 3% annually, while the Emerging Biopharma (EBP) segment is expected to grow 8-10% per year [21][22] - **TADs Business**: Comprises three main parts: data business (low growth), real-world evidence (double-digit growth), and analytics/consulting (mid-single digits) [26][27] - **Pricing Environment**: Stabilized after a period of volatility, with no significant pricing pressures currently reported [20] Strategic Partnerships - **Agreement with Veeva**: Resolved long-standing disputes to enhance collaboration, reflecting the need for integration between data and technology applications in the pharma ecosystem [28][29] Future Outlook - **2026 Growth Expectations**: Anticipated to deliver at least 5% growth, with a long-term growth target of 6-9% [30][32] - **EBITDA Margins**: Expected to remain flat with a potential for 30 basis points of expansion annually, influenced by business mix and operational efficiencies [32][36] Additional Insights - **Client Relationships**: Strong relationships with clients across the biopharma industry, contributing to confidence in future bookings and demand [12][36] - **Market Segmentation**: The market for EBP is larger than perceived, with opportunities in segments previously overlooked by IQVIA [18] This summary encapsulates the key points discussed during the IQVIA Holdings conference call, highlighting the company's performance, industry trends, and future outlook.

Enhabit (NYSE: EHAB) 2025 Conference Summary Company Overview - Enhabit operates in the home health and hospice industry, focusing on providing care services to patients in their homes. Key Points Industry Performance - The hospice segment has continued to outperform expectations, reinforcing the effectiveness of strategies implemented over the past few years [2][4] - Home health payer strategies are beginning to yield positive results, particularly in negotiations with various payers [2][4] Financial Performance - The company reported strong performance in 2025, with a focus on reducing leverage and improving free cash flow [2][5] - Hospice revenues increased by 20% in the quarter, driven by admissions and revenue per patient day [29] - The company anticipates low to mid-single-digit growth for home health and mid to high single-digit growth for hospice in the coming years [4] Proposed Rule Impact - The final rule from CMS is expected to be released by the end of November or early December, with expectations that it will be better than the proposed rule [6][8] - The proposed rule includes a potential 6.4% rate cut, which could create a headwind of $35 million to $40 million for the company [9][14] - Clarity on the final rule is critical for the company to strategize effectively and mitigate potential impacts [10][12] Margin and Cost Management - Hospice margins have benefited from increased volume on fixed costs, indicating durable margin profiles [5] - The company is implementing a pilot program to reduce visits per episode from 15 to 13, which could result in significant cost savings without compromising quality [11][39] Payer Relationships - The company has successfully renegotiated contracts with national payers, resulting in low double-digit increases in rates [17] - Most payer agreements are three-year contracts, with a preference for episodic arrangements to manage patient visits effectively [18] Labor Market and Workforce - The clinical workforce situation has improved compared to the pandemic years, with turnover rates returning to pre-pandemic levels [21][55] - Wage trends are stabilizing at a normal increase of 2.5% to 3% [52] Growth Strategy - Enhabit aims to open 10 new locations each year, with a focus on hospice services [37] - The company is prioritizing de novo strategies and expanding its footprint in markets where it already has home health services [34][36] Market Dynamics - The company has not observed significant changes in market dynamics despite the presence of larger competitors like Humana and UnitedHealth [22] - There is ongoing interest in the Medicare Advantage market, with potential stabilization in the transition back to fee-for-service models [23] M&A Opportunities - The company is exploring strategic M&A opportunities, particularly in smaller and medium-sized assets that do not command high multiples [60][61] - Clarity from the final rule is expected to facilitate better alignment between buyer and seller expectations in the market [62][63] Summary Outlook - Enhabit is positioned well for the end of 2025 and the start of 2026, with strong execution in hospice and improving metrics in home health [78][80] - The company is confident in its ability to navigate the proposed rule changes and maintain operational effectiveness [80]

Summary of enGene Holdings FY Conference Call Company Overview - **Company**: enGene Holdings (NasdaqCM: ENGN) - **Lead Product Candidate**: datolimogene hayemab - **Focus Area**: Bladder cancer, specifically non-muscle invasive bladder cancer (NMIBC) Key Points and Arguments Market Opportunity - The bladder cancer treatment market is expected to grow significantly due to new FDA guidance and the introduction of new agents, moving away from traditional treatments like BCG and radical cystectomy [4][6] - The target demographic primarily consists of elderly patients with comorbidities who prefer less invasive treatment options [4] Product Value Proposition - **Efficacy**: Datolimogene hayemab shows a competitive emerging efficacy profile, with a reported 62% complete response (CR) rate at six months, which is comparable to other agents in the market [12][20] - **Tolerability**: The product has a low treatment-related adverse event (AE) rate of 42% and a very low treatment interruption rate of 1.8%, indicating a favorable tolerability profile [21][23] - **Ease of Use**: The non-viral gene therapy approach simplifies handling for both doctors and patients, with no pre-washes or post-treatment requirements [5][6] Clinical Trial Updates - Enrollment in the Legend Pivotal cohort was completed with 125 patients, exceeding the target by 25% [11] - Protocol amendments were made to align with standard care and AUA guidelines, which are expected to enhance efficacy [14][16] - The primary endpoint has been aligned with other approved products, focusing on the CR rate at any time [19] Regulatory and Manufacturing Insights - The company is nearing completion of FDA validation runs for its manufacturing process, which utilizes a simple non-viral approach, allowing for cost-effective production [28][29] - The company holds RMAT designation, which may reduce the risk of receiving a Complete Response Letter (CRL) from the FDA [28] Commercialization Strategy - enGene plans to commercialize datolimogene hayemab independently in the U.S. with a manageable sales force of 40-50 representatives [34] - The company is exploring options for commercialization in Europe and plans to partner for markets outside the U.S. [34] Financial Position - enGene reported a cash position of approximately $225 million, which is expected to sustain operations into 2027 [37] Future Directions - The company is studying datolimogene hayemab in various patient cohorts, including naive and BCG-exposed patients, to gather more data on its efficacy across different populations [33] - Long-term data updates and FDA discussions are anticipated in the second half of the next year [26] Additional Important Insights - The competitive landscape for NMIBC treatments is evolving, with new products priced between $200 million to $700 million, indicating a large market potential [31] - The company is conducting extensive market research to shape its go-to-market strategy and understand the competitive environment better [35]

Summary of Oculis Holding (NasdaqGM:OCS) FY Conference Call Company Overview - Oculis is a biopharma company focused on neuro ophthalmology and ophthalmology, publicly listed on Nasdaq for two and a half years [4][2] - The company has three candidates in Phase III trials, with significant milestones expected from 2026 to 2028 [4][4] Key Assets and Mechanisms Privo Sector (Acute Optic Neuritis) - Privo Sector is a neuroprotective drug targeting acute optic neuritis, a condition often associated with multiple sclerosis (MS) [5][9] - The drug has shown promising results in preclinical and clinical trials, demonstrating neuroprotection and improved vision [16][16] - The market for acute optic neuritis is estimated to be between $6 billion to $7 billion, with no current competition [18][18] - The company plans to conduct two Phase III trials (PIONEER one and two) with a sample size of 180 to 200 patients each, expected to start recruitment within 12 months [31][31][54][54] Lecamilab (Dry Eye Disease) - Lecamilab is a TNF inhibitor targeting inflammation in dry eye disease, with a focus on a specific patient population identified by a biomarker [58][61] - The company aims to conduct a precision medicine approach, significantly reducing the patient population to 20% who are likely to respond positively to the treatment [59][61] - The ongoing PREDICT study is expected to read out results in the second half of next year [78][78] OCS O1 (Diabetic Macular Edema - DME) - OCS O1 is the first eye drop for retina in DME, currently in Phase III trials with readouts planned for Q2 next year [87][87] - The product aims to address early intervention in DME, targeting a larger patient population than currently treated [90][90] - The expected efficacy is comparable to existing treatments, with a goal of showing significant improvement in visual acuity [92][92] Financial Position - Oculis has a strong balance sheet with cash reserves expected to last until 2029, allowing the company to fund its six Phase III trials [98][98] Market Dynamics - The U.S. market for acute optic neuritis has approximately 60,000 to 70,000 patients annually, with pricing for orphan indications ranging from $100,000 to $400,000 [36][37] - The company has identified a small number of neuro-ophthalmologists (420) who will be able to prescribe its products, indicating a focused market entry strategy [38][38] Strategic Focus - Oculis plans to prioritize the Privo Sector while exploring partnerships for commercialization outside the U.S. [96][96] - The company aims to maintain a strong position before seeking partnerships, particularly after the readout of its DME trial [97][97] Conclusion - Oculis is positioned to make significant advancements in the treatment of acute optic neuritis, dry eye disease, and diabetic macular edema, with a robust pipeline and financial backing to support its clinical trials and market entry strategies [99][99]

AMD Strategy and Vision - AMD aims to drive accelerated growth and deliver shareholder value[3] - The company expects leadership in high-performance and AI computing[3] - AMD anticipates growth and opportunities in the total addressable market[3] - AMD's goal is to deliver significant value to its shareholders[3] Financial Expectations - The presentation includes expectations of AMD's financial plans and long-term financial model, including compound annual growth rate, revenue market share, non-GAAP gross margin, non-GAAP operating margin, non-GAAP effective tax rate, non-GAAP FCF margin and non-GAAP earnings per share[3] - Projected 2025 non-GAAP gross profit and operating profit exclude $800 million inventory and related charges associated with U S export restrictions recognized in Q2'25[5] - AMD uses a projected non-GAAP tax rate of 13-15% for its long-term financial model[5] Meeting Agenda - The AMD Financial Analyst Meeting 2025 includes presentations on AMD's vision and growth strategy, technology strategy, data center leadership, AI leadership, networking, client, graphics, embedded transformation, and financial momentum[6]

THIRD QUARTER EARNINGS CALL NOVEMBER 11, 2025 OXY Cautionary statements Forward-Looking Statements This presentation contains "forward"-doking datements" withint temaning of the "safe factor" frouslisones of the Private Securities Libradition subt od initied to statemen (Ocodential ar Cav ) excectations, belefo; stars or for or of obsings statements in oly e estimates, expectains, probections, probections, robas and unertrianties. Actual seults, screetines materially: Forward-trading and dther strements reg ...

FedEx FY Conference Summary Company Overview - **Company**: FedEx (NYSE: FDX) - **Date of Conference**: November 11, 2025 Key Points Industry Context - FedEx operates in the logistics and transportation industry, which has seen significant changes due to the pandemic and evolving global supply chain dynamics [5][6][7] - The company moves $2 trillion worth of commerce and connects 3 million shippers to 225 million consumers, positioning itself as a central player in global supply chains [5][6] Strategic Strengths and Changes - FedEx has built a robust network over 50 years, which is difficult to replicate, and has become integral to global supply chains [5][6] - The pandemic has shifted supply chain discussions to boardroom levels, highlighting FedEx's role in the industrial economy [6][7] - The company has successfully reduced structural costs, achieving operating income growth even with declining revenue, marking a historical first for FedEx [8][9] - FedEx is evolving its networks to be more flexible and intelligent, referred to as Network 2.0 and Tricolor [9][10] Technological Advancements - FedEx is leveraging its data from 17 million packages processed daily to enhance logistics intelligence and support AI applications [10][37] - The company is focusing on automation in its operations, particularly in its ground hubs, to improve efficiency and reduce manual handling [35][36] Market Adaptability - FedEx is adapting to changing global supply chain patterns, with a notable shift in traffic from Trans-Pacific routes to Intra-Asia routes [15][16] - The company is the largest broker in America, emphasizing its operational capabilities to provide seamless customer experiences [16][17] Financial Performance and Guidance - In Q1, FedEx reported a $150 million adjusted operating income impact and anticipates a total of $1 billion impact due to trade policy headwinds [19][21] - U.S. outbound air freight volumes increased by 22%, contributing approximately $40 million to revenue [19][20] - The company expects modest demand for the peak season, with improvements in operational metrics compared to previous years [25][27] Trade Policy Impact - The recent U.S.-China trade deal is expected to provide some certainty, but its immediate impact on FedEx's operations remains unclear [21][22] - FedEx is focused on managing the $1 billion headwind while continuing to leverage its strengths in the industrial economy [23][22] Spin-off Plans - FedEx plans to spin off its freight division to create two independent companies, aiming to unlock value for shareholders and allow each entity to focus on its core strengths [40][41] - The management team for the freight division has been assembled, emphasizing experienced leadership to drive growth [41] Upcoming Events - FedEx will hold two investor days: one for FedEx Corporation (excluding freight) on February 11-12, 2026, in Memphis, and another for FedEx Freight in the spring of 2026 in New York [43] Additional Insights - FedEx's commitment to safety is highlighted in its handling of aircraft inspections amid regulatory challenges [28][30] - The company is actively working with partners to enhance its service offerings, particularly in healthcare logistics, where it has seen significant growth [37][39]