Faruqi & Faruqi, LLP Securities Litigation Partner James (Josh) Wilson Encourages Investors Who Suffered Losses In aTyr To Contact Him Directly To Discuss Their Options If you purchased or acquired securities in aTyr between January 16, 2025 and September 12, 2025 and would like to discuss your legal rights, call Faruqi & Faruqi partner Josh Wilson directly at 877-247-4292 or 212-983-9330 (Ext. 1310). [You may also click here for additional information] NEW YORK, Oct. 10, 2025 (GLOBE NEWSWIRE) -- Faruqi & ...

MIAMI, Oct. 10, 2025 (GLOBE NEWSWIRE) -- The law firm of Shamis & Gentile, P.A. alerts investors that a securities class action lawsuit has been filed against aTyr Pharma, Inc. (NASDAQ: ATYR) on behalf of investors who purchased or otherwise acquired aTyr Pharma common stock between January 16, 2025 and September 12, 2025, inclusive. The lead plaintiff deadline for this action is December 8, 2025. For more information go to:aTyr Pharma Securities Class Action    Impacted investors may also contact attorney ...

Core Viewpoint - Robbins LLP has initiated a class action lawsuit on behalf of investors who purchased aTyr Pharma, Inc. common stock between January 16, 2025, and September 12, 2025, alleging that the company misled investors regarding the efficacy of its drug candidate, Efzofitimod [1][2]. Allegations - The lawsuit claims that aTyr Pharma provided misleading information about the Phase 3 study of Efzofitimod, which was designed to evaluate its safety and efficacy in patients with pulmonary sarcoidosis. The company's executives expressed confidence in the study's design while allegedly concealing the drug's inability to allow patients to taper off steroids completely [2]. - On September 15, 2025, aTyr announced that the EFZO-FIT study did not meet its primary endpoint, specifically the change from baseline in mean daily OSC dose at week 48. Following this announcement, the stock price plummeted from $6.03 per share on September 12, 2025, to $1.02 per share on September 15, 2025, marking an 83.2% decline in a single day [3]. Next Steps - Shareholders interested in serving as lead plaintiffs in the class action must submit their papers to the court by December 8, 2025. Participation in the case is not required to be eligible for recovery, and shareholders can choose to remain absent class members [4]. About Robbins LLP - Robbins LLP is recognized for its leadership in shareholder rights litigation, focusing on helping shareholders recover losses and improve corporate governance since 2002 [5].

Director Paul Schimmel's purchase of 317,999 shares signals insider confidence in aTyr Pharma, Inc. (NASDAQ:ATYR)'s future prospects.The company is currently involved in a class action lawsuit, which could affect investor sentiment and its reputation.aTyr's financials show challenges with a negative P/E ratio of -1.29 and a negative enterprise value to operating cash flow ratio of -1.60, but it maintains a low debt-to-equity ratio of 0.17 and a strong current ratio of 5.63.aTyr Pharma, Inc. (NASDAQ:ATYR) is ...

Core Viewpoint - A federal class-action lawsuit has been filed against aTyr Pharma, Inc. following an 83% drop in its stock price after its lead drug candidate failed to meet primary endpoints in a Phase 3 trial [1][7]. Group 1: Lawsuit Details - The lawsuit, titled Munguia v. aTyr Pharma Inc., alleges that aTyr and its executives made false and misleading statements regarding the efficacy of its drug Efzofitimod, leading to inflated stock prices [2][5]. - The proposed class includes all investors who acquired aTyr common stock between January 16, 2025, and September 12, 2025 [3]. - The allegations center around aTyr's Phase 3 study, EFZO-FIT, which evaluated Efzofitimod in patients with pulmonary sarcoidosis [3]. Group 2: Company Statements and Market Reaction - Throughout the class period, aTyr executives expressed confidence in the study's design and the drug's potential to reduce steroid dependency [4]. - The lawsuit claims that while making optimistic statements, aTyr was concealing adverse facts about Efzofitimod's efficacy, which constitutes a violation of securities laws [5]. - The negative results from the EFZO-FIT study were disclosed on September 15, 2025, leading to a drastic decline in stock price from $6.03 to $1.02, a drop of 83.2% [6][7]. Group 3: Investigation and Market Opportunity - Hagens Berman is investigating whether aTyr misled investors regarding trial data and the drug's market potential, which was emphasized as a multi-billion-dollar opportunity [8]. - The firm is urging investors who suffered losses or have relevant information to come forward [9].

Core Viewpoint - A class action lawsuit has been filed against aTyr Pharma, Inc. due to misleading statements regarding the efficacy of its drug Efzofitimod, which failed to meet its primary endpoint in a clinical study [1][2][3]. Company Information - aTyr Pharma, Inc. is facing legal action for allegedly providing false and misleading information to investors about the drug Efzofitimod, particularly regarding its ability to allow patients to taper off steroid usage [2]. - The company announced disappointing results from the EFZO-FIT study on September 15, 2025, revealing that it did not meet its primary endpoint related to mean daily OSC dose reduction at week 48 [3]. Stock Performance - Following the announcement of the study results, aTyr's stock price plummeted from $6.03 per share on September 12, 2025, to $1.02 per share on September 15, 2025, marking a significant decline of 83.2% in just one day [4]. Legal Context - Investors who purchased aTyr's common stock between January 16, 2025, and September 12, 2025, are eligible to participate in the class action lawsuit, with a deadline to request lead plaintiff status by December 8, 2025 [4]. Firm Background - Levi & Korsinsky, LLP has a strong track record in securities litigation, having secured hundreds of millions of dollars for shareholders over the past 20 years and consistently ranking among the top securities litigation firms in the United States [5].

Core Viewpoint - aTyr Pharma, Inc. experienced a dramatic decline in share price, dropping over 80% after failing to meet the primary endpoint in its late-stage study of efzofitimod for pulmonary sarcoidosis treatment [1][7]. Company Summary - On September 15, 2025, aTyr announced that its EFZO-FIT trial did not achieve statistical significance in steroid reduction after a year of tapering, leading to a significant market reaction [7]. - The company had previously assured investors that its Phase 2 data was among the best seen by experts and highlighted a multi-billion-dollar market opportunity for efzofitimod [6]. Investigation Summary - Following the market reaction, Hagens Berman, a national shareholders rights firm, initiated an investigation into whether aTyr misled investors regarding its Phase 2 data and Phase 3 trial design [2][5]. - The investigation is focused on the accuracy of aTyr's disclosures about the quality of its Phase 2 data and the design of the EFZO-FIT trial [5]. Market Reaction - The announcement of the topline results led to a flood of analyst downgrades and a catastrophic drop in aTyr's share price, reflecting investor disappointment and loss of confidence [7].

Core Insights - The Phase 3 EFZO-FIT™ study of efzofitimod demonstrated clinical benefits in patients with pulmonary sarcoidosis, particularly in improving fatigue and general health scores at week 48 compared to placebo [2][3][4] - Despite not meeting the primary endpoint of reducing mean daily oral corticosteroid dose, efzofitimod showed potential to improve multiple disease-related health outcomes, including cough, shortness of breath, and fatigue [3][4] Company Overview - aTyr Pharma, Inc. is a clinical stage biotechnology company focused on developing first-in-class medicines from its proprietary tRNA synthetase platform [2][9] - The company is investigating efzofitimod, a biologic immunomodulator, for treating interstitial lung disease (ILD), which includes pulmonary sarcoidosis and systemic sclerosis-related ILD [8][9] Study Findings - The study involved 268 patients and presented significant improvements in the Fatigue Assessment Scale Total Score (p=0.0226) and King's Sarcoidosis Questionnaire-General Health score (p=0.0197) for the 5.0 mg/kg efzofitimod treatment group [2][3][4] - Additional outcomes included a trend towards a greater proportion of patients achieving steroid-free status for at least six months and improvements in KSQ-Lung score [3][4] Treatment Context - Pulmonary sarcoidosis affects approximately 200,000 Americans, with current treatments primarily involving corticosteroids, which have limited efficacy and significant side effects [6][7] - Efzofitimod aims to provide a safer and more effective treatment option for patients with pulmonary sarcoidosis, potentially reducing reliance on chronic steroids [3][8]

Core Insights - aTyr Pharma, Inc. experienced a significant drop in share price, over 80%, following the announcement that its late-stage study of efzofitimod for pulmonary sarcoidosis did not meet its primary endpoint [1][5] Company Developments - The company reported that the topline results of the EFZO-FIT trial failed to achieve statistical significance in steroid reduction after a year of forced tapering, with placebo tapering outperforming the company's projections [5] - aTyr had previously assured investors that its Phase 2 data was among the best seen by experts and emphasized a multi-billion-dollar market opportunity for efzofitimod [4] Market Reaction - Following the disappointing trial results, the market reacted sharply, leading to a significant decline in aTyr's share price and prompting numerous analyst downgrades [5] Legal Investigation - Hagens Berman, a national shareholders rights firm, has initiated an investigation into whether aTyr misled investors regarding the Phase 2 data and the design of the Phase 3 EFZO-FIT trial [2][6] - The firm is encouraging investors who suffered losses to come forward and is seeking information from individuals who may assist in the investigation [2][6]

NEW YORK, Sept. 24, 2025 (GLOBE NEWSWIRE) -- Pomerantz LLP is investigating claims on behalf of investors of  aTyr Pharma, Inc. (“aTyr” or the “Company”) (NASDAQ: ATYR).  Such investors are advised to contact Danielle Peyton at newaction@pomlaw.com or 646-581-9980, ext. 7980. The investigation concerns whether aTyr and certain of its officers and/or directors have engaged in securities fraud or other unlawful business practices.  [Click here for information about joining the class action] On September 15, 2 ...