Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 __________________________________________________ FORM 10-Q __________________________________________________ (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-36536 __ ...

CareDx, Inc (NASDAQ:CDNA) Q1 2022 Earnings Conference Call May 5, 2022 4:30 PM ET Company Participants Ian Cooney - VP of IR Reg Seeto - CEO Ankur Dhingra - CFO Conference Call Participants Alex Nowak - Craig-Hallum Capital Andrew Cooper - Raymond James Mason Carrico - Stephens Inc. Operator Good day, and welcome to the CareDx First Quarter 2022 Earnings Conference Call. All participants will be in listen-only mode. [Operator Instructions] Please note this event is being recorded. I would now like to turn t ...

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 __________________________________________________ FORM 10-Q __________________________________________________ (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-36536 _ ...

Financial Data and Key Metrics Changes - CareDx reported Q4 2021 revenues of $79.2 million, a 35% increase year-over-year, and full-year revenues of $296.4 million, representing a 54% growth [7][42] - Adjusted EBITDA for Q4 was negative $1.4 million, compared to positive $4.9 million in Q4 2020, while full-year adjusted EBITDA was $17.8 million, up from $8 million in 2020 [10][50] - Non-GAAP gross margins for Q4 were 68.4%, down from 70.3% in Q4 2020, attributed to the adoption of new tests and expansion of laboratory capacity [45] Business Line Data and Key Metrics Changes - Testing Services revenue grew 58% year-over-year to $259 million, with testing volumes increasing by 94% to approximately 153,000 tests [42] - Product revenues increased by 39% to approximately $27 million, with over 55% of this revenue coming from the AlloSeq growth franchise [32][43] - Patient and Digital Solutions revenues were above $10 million, an 11% increase compared to 2020 [44] Market Data and Key Metrics Changes - Q4 saw a record testing services volume of 41,900 tests, a 67% year-over-year growth, despite a sequential decline in transplant volumes due to the Omicron surge [7][10] - Kidney transplants were down 4% and heart transplants down 2% sequentially in Q4 compared to Q3 [7] Company Strategy and Development Direction - CareDx's strategic goals include deepening competitive moats around transplant centers, raising innovation standards, and digitally connecting patients [11] - The company aims to connect one in two transplant patients, with significant progress in digital solutions and patient management [26][31] - CareDx is focusing on multimodal innovation across organ transplants, with recent advancements in AlloSure and AlloMap tests [16][18] Management's Comments on Operating Environment and Future Outlook - Management acknowledged the impact of COVID-19 on transplant volumes, particularly in January 2022, but expressed optimism for recovery as staffing and operational capacities improve [57][90] - The company expects revenues for 2022 to range between $330 million and $350 million, driven by double-digit growth in core kidney and heart franchises [56] Other Important Information - CareDx has made several acquisitions to enhance its portfolio, including those focused on medication adherence and digital solutions [51][30] - The company is actively addressing equity in transplant care, partnering with organizations to improve access for minorities [37][38] Q&A Session Summary Question: What are the assumptions for lung reimbursement in guidance? - Management assumed minimal contribution from the lung test, around 1% growth [61] Question: How is competition factored into guidance? - Management expects to maintain market share despite competition, with a focus on expanding protocols and patient connections [62][66] Question: What is the outlook for transplant volumes? - Management noted a significant decline in transplant volumes in January but observed improvements in February, anticipating a recovery [73][90] Question: What is the impact of legal spending? - Legal spending is influenced by ongoing litigation and government requests, with a trial related to false advertising upcoming [85][96] Question: Will operating expenses continue to increase? - Management confirmed that operating expenses are expected to rise as the company invests in growth and scaling operations [102]

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 ________________________________________________________________________________________________________ Form 10-K ________________________________________________________________________________________________________ (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF TH ...

CareDx, Inc. (NASDAQ:CDNA) Q3 2021 Earnings Conference Call October 28, 2021 4:30 PM ET Company Participants Ian Cooney - Investor Relations Reg Seeto - President and Chief Executive Officer Ankur Dhingra - Chief Financial Officer Conference Call Participants Matt Sykes - Goldman Sachs Alex Nowak - Craig-Hallum Capital Group Mark Massaro - BTIG Andrew Cooper - Raymond James Yi Chen - H.C. Wainwright Operator Greetings, and welcome to the CareDx, Incorporated Third Quarter 2021 Earnings Conference Call. [Ope ...

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 __________________________________________________ FORM 10-Q __________________________________________________ (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-365 ...

CareDX, Inc. (NASDAQ:CDNA) Q2 2021 Earnings Conference Call July 29, 2021 4:30 PM ET Company Participants Ian Cooney - Investor Relations Reg Seeto - President and Chief Executive Officer Ankur Dhingra - Chief Financial Officer Conference Call Participants Andrew Cooper - Raymond James Matt Sykes - Goldman Sachs Steven Mah - Piper Sandler Brandon Couillard - Jefferies Alex Nowak - Craig-Hallum Capital Group Mark Massaro - BTIG Yi Chen - H.C. Wainwright Operator Greetings, and welcome to the CareDx, Inc. Sec ...

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 __________________________________________________ FORM 10-Q __________________________________________________ (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-36536 __ ...

The Allo-Transplantation Company Focused on better outcomes through personalized transplant surveillance May 2021 Allo-transplant (allo- meaning "other" in Greek) is the transplantation of cells, tissues or organs to a recipient from a genetically non-identical donor of the same species Dx® Safe Harbor Statement These slides and the accompanying oral presentation contain forward-looking statements. All statements other than statements of historical fact contained in this presentation, including statements r ...