HOUSTON, Feb. 05, 2026 (GLOBE NEWSWIRE) -- FibroBiologics, Inc. (Nasdaq: FBLG) (“FibroBiologics” or the “Company”), a clinical-stage biotechnology company with 270+ patents issued and pending with a focus on the development of therapeutics and potential cures for chronic diseases using fibroblasts and fibroblast-derived materials, today announced that the Canadian Intellectual Property Office has issued Canadian Patent No. 3118732, titled “Treatment of Cachexia Using Fibroblast Cells and Products Thereof.” ...

Company Overview - FibroBiologics, Inc. is a clinical-stage biotechnology company based in Houston, focusing on developing therapeutics and potential cures for chronic diseases using fibroblasts and fibroblast-derived materials [3] - The company holds over 270 patents issued and pending in the US and internationally, covering various clinical pathways such as wound healing, multiple sclerosis, disc degeneration, psoriasis, orthopedics, human longevity, and cancer [3] Upcoming Events - The CEO, Pete O'Heeron, will present at the DealFlow Discovery Conference on January 28-29, 2026, in Atlantic City, New Jersey [1] - FibroBiologics will deliver a company presentation on January 29 at 11:30 a.m. ET and will be available for one-on-one investor meetings throughout the event [2]

Group 1: Market Movements - Several biotech and healthcare companies experienced notable gains in after-hours trading, driven by earnings updates, guidance announcements, and broader investor sentiment [1] - FibroBiologics, Inc. (FBLG) led with a 7.68% increase, closing at $0.41, suggesting speculative interest or technical momentum [1] - Nyxoah SA (NYXH) advanced 3.94% to $5.28 after reporting preliminary results for Q4 and full year 2025, along with revenue guidance for Q1 2026 [2] - Fortress Biotech, Inc. (FBIO) climbed 6.90% to $4.49, continuing a trend of volatility despite no new news [2] - Revvity, Inc. (RVTY) gained 4.92% to close at $109.00, with investors likely reacting to a previous collaboration announcement with Eli Lilly [3] - Option Care Health, Inc. (OPCH) rose 3.28% to $33.11 after releasing preliminary unaudited financial results for Q4 and full year 2025, along with guidance for 2026 [4] - Actinium Pharmaceuticals, Inc. (ATNM) added 3.02% to close at $1.34, reflecting investor activity in the broader biotech sector [4] - Design Therapeutics, Inc. (DSGN) gained 1.97% to $9.30, indicating continued interest despite no specific news [5] Group 2: Company-Specific Developments - FibroBiologics, Inc. (FBLG) showed a significant rise without any company-specific news, indicating potential speculative interest [1] - Nyxoah SA (NYXH) provided revenue guidance for Q1 2026, which bolstered investor confidence in its growth trajectory [2] - Revvity, Inc. (RVTY) is expanding access to predictive models through a collaboration with Eli Lilly, aimed at accelerating AI-enabled drug discovery [3] - Option Care Health, Inc. (OPCH) released preliminary financial results and guidance, contributing to its positive after-hours reaction [4]

Core Insights - FibroBiologics is focused on developing fibroblast-based therapies for chronic diseases, emphasizing innovation and patient impact in 2025 [2][3] Company Progress - The company expanded its laboratory in Houston to over 10,000 square feet, enhancing its R&D capabilities and in-house manufacturing [3] - FibroBiologics raised significant capital through multiple registered direct offerings, totaling $7.2 million in late 2025, and eliminated all outstanding debt [3] - Jason D. Davis was appointed as CFO, bringing extensive experience in corporate finance and capital markets [3] - The company actively presented its research at various conferences, enhancing its visibility in the biotech community [3] Clinical Trials and Milestones - FibroBiologics completed the CYWC628 master and working cell banks, which are crucial for its wound healing program [4] - The company received HREC approval for a Phase 1/2 trial in Australia for CYWC628, targeting diabetic foot ulcers with a study of 120 patients [4] - Positive IND-enabling data for CYPS317 indicated efficacy comparable to biologics, leading to a new IND filing on December 30, 2025 [4] - Progress was made on CYMS101 for multiple sclerosis, with plans for an IND submission [4] Scientific Advancements - The company confirmed remyelination in brain tissue repair models, supporting its approach for treating demyelinating diseases [5] - Advances in the bone marrow organoid platform showed potential in reducing tumor sizes and addressing age-related immune decline [5] Intellectual Property - FibroBiologics holds over 270 patents issued and pending, covering various therapeutic areas including wound healing and human longevity [6] - Recent patent filings include methods for generating multipotent cells from fibroblasts and a fibroblast-based chondrocyte spheroid platform for musculoskeletal conditions [6] Financial Overview - The company reported disciplined execution in its quarterly reports, with R&D expenses focused on lab expansion and cell bank development [7] - Financing efforts included closing two tranches of a $25 million financing round [7] Future Outlook - The company aims to execute clinical trials, submit INDs, and strengthen its financial position in 2026 [8] - Challenges such as regulatory hurdles and funding are acknowledged, but the company expresses confidence in overcoming these obstacles [8]

HOUSTON, Jan. 06, 2026 (GLOBE NEWSWIRE) -- FibroBiologics, Inc. (Nasdaq: FBLG) (“FibroBiologics” or the “Company”), a clinical-stage biotechnology company with 270+ patents issued and pending with a focus on the development of therapeutics and potential cures for chronic diseases using fibroblasts and fibroblast-derived materials, today announced that Founder and Chief Executive Officer, Pete O’Heeron, will present at the 9th Annual BFC Global Healthcare Business Development and Investment Conference taking ...

FSdC demonstrated statistically significant and superior improvement in disc preservation and structural integrity compared to other treatmentsHOUSTON, Jan. 05, 2026 (GLOBE NEWSWIRE) -- FibroBiologics, Inc. (Nasdaq: FBLG) (“FibroBiologics”), a clinical-stage biotechnology company with 270+ patents issued and pending with a focus on the development of therapeutics and potential cures for chronic diseases using fibroblasts and fibroblast-derived materials, today announced positive preclinical results for FSdC ...

Core Viewpoint - FibroBiologics has filed a Phase 1/2 Investigational New Drug (IND) application with the FDA for CYPS317, a fibroblast spheroid-based therapy aimed at treating moderate to severe psoriasis, marking a significant step in its chronic inflammatory disease pipeline [1][2][3] Group 1: Company Developments - The IND filing is a major advancement for FibroBiologics, following positive preclinical results that indicate CYPS317 can significantly reduce psoriasis severity and relapse [2] - The IND submission includes comprehensive data on pharmacology, safety, and manufacturing, supporting the therapeutic's mechanism of action and safety profile [3] - The company aims to advance first-in-human clinical trials for CYPS317 after FDA review [3] Group 2: Market Context - Psoriasis affects over eight million adults in the U.S., significantly impairing quality of life and productivity, with existing therapies still leaving unmet needs [4] - The filing of the IND application is seen as a pivotal transition from preclinical research to clinical development for CYPS317, with the potential to redefine treatment for chronic inflammatory disorders [5] Group 3: Scientific Insights - Preclinical data suggest that CYPS317 combines extracellular matrix signaling with immunomodulation, potentially restoring tissue homeostasis in chronic inflammatory conditions like psoriasis [5] - The therapy's single dose has shown effects that match or exceed those of multiple doses of existing anti-IL-23 monoclonal antibodies, indicating its durability and immunomodulatory capacity [2]

As filed with the Securities and Exchange Commission on December 23, 2025. Registration No. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 FibroBiologics, Inc. (Exact name of registrant as specified in its charter) (State or other jurisdiction of incorporation or organization) (I.R.S. Employer Identification Number) 455 E. Medical Center Blvd. Suite 300 Houston, Texas 77598 (281) 671-5150 Delaware 2834 86-3329066 (Prim ...

Core Viewpoint - FibroBiologics, Inc. has successfully closed a registered direct offering of 5,227,275 shares of common stock at $0.33 per share, raising approximately $1.7 million in gross proceeds, with additional potential proceeds from unregistered warrants [1][3]. Group 1: Offering Details - The registered direct offering involved 5,227,275 shares priced at $0.33 each, with concurrent private placement of unregistered warrants for the same number of shares at the same exercise price [1]. - The total gross proceeds from the offering are approximately $1.7 million before deducting fees and expenses, with potential additional proceeds of $1.7 million from the unregistered warrants if fully exercised [3]. - The unregistered warrants will be exercisable upon stockholder approval and will expire five years after such approval [1]. Group 2: Regulatory and Legal Aspects - The shares offered in the registered direct offering were made under a "shelf" registration statement filed with the SEC, which became effective on February 10, 2025 [4]. - The unregistered warrants and shares from the private placement were offered under Section 4(a)(2) of the Securities Act and have not been registered, thus cannot be sold in the U.S. without registration or an exemption [5]. Group 3: Company Overview - FibroBiologics is a clinical-stage biotechnology company focused on developing therapeutics for chronic diseases using fibroblast cells, holding over 270 patents [9]. - The company aims to advance medical treatments in areas such as wound healing, multiple sclerosis, and cancer through its innovative cell therapy and tissue regeneration approaches [9].

Core Viewpoint - FibroBiologics, Inc. has announced a registered direct offering of 5,227,275 shares of common stock at $0.33 per share, along with a concurrent private placement of unregistered warrants for the same number of shares at the same exercise price, aiming to raise approximately $1.7 million in gross proceeds [1][3]. Group 1: Offering Details - The company will issue 5,227,275 shares of common stock at an offering price of $0.33 per share in a registered direct offering [1]. - Concurrently, unregistered warrants will be issued to purchase up to 5,227,275 shares at an exercise price of $0.33 per share, which will be exercisable upon stockholder approval [1]. - The closing of the offering is expected on or about December 16, 2025, subject to customary closing conditions [1]. Group 2: Financial Implications - The aggregate gross proceeds from the offering are expected to be approximately $1.7 million before deducting fees and expenses [3]. - If the unregistered warrants are fully exercised, additional gross proceeds of approximately $1.7 million could be realized [3]. - The net proceeds from the offering will be used for working capital and general corporate purposes [3]. Group 3: Regulatory Information - The shares offered in the registered direct offering are being made under a "shelf" registration statement that became effective on February 10, 2025 [4]. - The unregistered warrants and shares issuable upon their exercise are being offered in a private placement and have not been registered under the Securities Act [5]. Group 4: Company Overview - FibroBiologics is a clinical-stage biotechnology company focused on developing therapeutics for chronic diseases using fibroblast cells and materials, holding over 270 patents [9]. - The company is involved in various clinical pathways, including wound healing, multiple sclerosis, and cancer, representing advancements in cell therapy and tissue regeneration [9].