historical facts. Such forward-looking statements, which are based upon the current beliefs and expectations of PAVmed's management, are subject to risks and uncertainties, which could cause actual results to differ from the forward-looking statements. Risks and uncertainties that may cause such differences include, among other things, volatility in the price of PAVmed's common stock; general economic and market conditions; the uncertainties inherent in research and development, including the cost and time ...

Company Developments - PAVmed Inc. (NASDAQ:PAVM) experienced a stock price surge to $16.12, marking a 160.42% increase, driven by a contract secured by its subsidiary, Lucid Diagnostics, with the U.S. Department of Veterans Affairs for the EsoGuard® Esophageal DNA Test [1][7] - Namib Minerals Ordinary Shares (NASDAQ:NAMM) saw a 145.95% increase in stock price to $2.41, with a trading volume of 103,136,334, indicating heightened investor interest possibly due to strategic developments or metal price fluctuations [2][7] - Global Interactive Technologies, Inc. (NASDAQ:GITS) reported a 93.32% rise in stock price to $1.66, reflecting growing investor interest in tech and entertainment platforms, particularly those related to K-POP and modern Korean culture [3][7] - Lisata Therapeutics, Inc. (NASDAQ:LSTA) experienced an 87.27% increase in stock price to $4.04, suggesting positive market reception for its focus on cellular therapies, despite ongoing investigations into the company [4][7] - Namib Minerals Warrants (NASDAQ:NAMMW) saw a 66.78% increase in price to $0.15, indicating investor optimism in leveraging warrants for potential gains in the mining sector [5][7] Market Dynamics - The significant price changes across these companies reflect diverse sector interests, including healthcare, biotechnology, technology, and basic materials, driven by factors such as innovative product pipelines and strategic company developments [6]

PAVmed Inc (NASDAQ: PAVM) shares more than quadrupled on Wednesday after the company's subsidiary – Lucid Diagnostics – secured a major contract from the US government. ...

Market Overview - U.S. stocks showed mixed performance with the Dow up 0.30% to 48,632.75, the S&P 500 rising 0.16% to 6,807.83, while the Nasdaq fell 0.06% to 22,940.77 [1] - European shares were also mixed, with the eurozone's STOXX 600 gaining 0.03% and Germany's DAX falling 0.47% [8] - Asian markets closed mixed, with Japan's Nikkei down 0.41% and Hong Kong's Hang Seng Index up 0.37% [11] Sector Performance - Energy shares increased by 2% on Wednesday, while consumer staples stocks dipped by 0.5% [2] Company Earnings - Johnson & Johnson reported fourth-quarter earnings of $2.46 per share, a 20.6% increase year-over-year, surpassing the consensus estimate of $2.44 [3] - The company also reported sales of $24.56 billion, up 9.1% year-over-year, exceeding the consensus of $24.16 billion [3] - For fiscal 2026, Johnson & Johnson provided adjusted earnings guidance of $11.43-$11.63, slightly above the consensus of $11.45, and expects sales of $99.50 billion-$100.5 billion compared to the consensus of $98.89 billion [4] Notable Stock Movements - PAVmed Inc shares surged 246% to $21.43 after a contract award for its EsoGuard Esophageal DNA Test [10] - Progress Software Corp shares rose 22% to $47.08 following better-than-expected fourth-quarter results and positive guidance [10] - Lisata Therapeutics Inc shares increased by 86% to $4.01 after announcing a binding term sheet for acquisition [10] - Venus Concept Inc shares dropped 55% to $1.99 due to plans to delist from Nasdaq [10] - Gibraltar Industries Inc shares fell 18% to $44.70 after reporting preliminary fourth-quarter results below estimates [10]

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Group 1 - The special meeting of stockholders for PAVmed Inc. is called to order by the Chairman and CEO, Lishan Aklog, with key personnel present [1] - The meeting is conducted via live webcast, allowing stockholders to participate remotely [1] - Michael Gordon, the General Counsel, outlines the voting process and opportunities for stockholders to submit questions during the meeting [2]

Core Insights - Several small-cap biotech and healthcare stocks experienced significant gains in after-hours trading on November 28, 2025, despite a lack of new news [1] Company Summaries - **BioAtla Inc. (BCAB)**: Shares surged 13.94% to $1.03 after closing at $0.9040, up 6.27%. The increase may be linked to financing agreements announced on November 21, including a $7.5 million advance and a Standby Equity Purchase Agreement allowing for the sale of up to $15 million in common stock at a 3% discount [2] - **Metagenomi Inc. (MGX)**: Stock rose 5.71% to $1.85 after a 3.55% gain to $1.75 during regular trading. The movement appears driven by investor sentiment or technical factors, with no new corporate updates [3] - **PAVmed Inc. (PAVM)**: Advanced 5.72% to $0.3900, recovering from a slight decline earlier in the day. The company reported a GAAP net loss of $6.3 million, or $(0.29) per share, with revenue dropping sharply to $5,000 from $996,000 year-over-year [4] - **Precision BioSciences, Inc. (DTIL)**: Gained 2.94% to $5.60, building on a 6.46% rise to $5.44. The company is set to present Phase 1 data from its ELIMINATE-B trial at the Hep-DART 2025 meeting, which may be boosting investor optimism [5] - **Reviva Pharmaceuticals Holdings, Inc. (RVPH)**: Edged up 2.04% to $0.57 after a 7.66% gain to $0.5625. The company narrowed its quarterly net loss to $4.0 million, or $0.06 per share, compared to $8.4 million, or $0.25 per share, in the prior year [6] - **Sonnet BioTherapeutics Holdings, Inc. (SONN)**: Rose 5.11% to $3.91, recovering from a 10.47% decline earlier in the day. The company adjourned a special meeting to allow more time for voting on a proposed combination with Hyperliquid Strategies Inc. and Rorschach I LLC, with over 95% of shares voting in favor [7] - **Entero Therapeutics, Inc. (ENTO)**: Gained 3.68% to $3.10 after a 5.28% rise to $2.99. The company announced a rebranding to GridAI Technologies Corp., effective December 1, 2025, following its acquisition of GRID AI Corp. The new ticker symbol "GRDX" will debut on the Nasdaq Capital Market [8]

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Financial Data and Key Metrics Changes - The company reported a GAAP net loss of $6 million for the third quarter, which includes a non-cash loss of $4.4 million due to changes in the fair value of equity investments [23][24] - Non-GAAP loss for the quarter was $446,000, primarily reflecting incremental contractor development costs for the Veris implantable device [24][25] - Cash burn rate for the third quarter was $900,000, which included approximately $500,000 in outside contractor development costs for the implantable device [20][25] Business Line Data and Key Metrics Changes - Lucid's revenue for the quarter was $1.2 million, with test volume exceeding 2,800, consistent with the target range of 2,500-3,000 tests [10][11] - Veris launched the commercial phase of its strategic partnership with OSU, targeting 1,000 patients in the first year for enrollment in a registry [12][14] Market Data and Key Metrics Changes - The company remains the largest shareholder of Lucid Diagnostics, owning approximately 23% of the common shares outstanding, with a 28% voting interest [21][22] - Lucid's stock price experienced a sequential reduction of $4.4 million, impacting the equity method investment balance [20][22] Company Strategy and Development Direction - The company aims to stabilize its corporate structure and balance sheet, with plans to operate as a diversified commercial life sciences company with multiple independently financed subsidiaries [5][6] - A licensing agreement with Duke University and the University of North Carolina for breakthrough endoscopic imaging technology is in the final stages, which could transform treatment for esophageal precancer [8][46] - The company is expanding its commercial offerings for Veris beyond remote patient monitoring to include clinical support services and AI-based clinical decision tools [17][43] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the company's ability to complete its restructuring and reignite its broader vision, with several promising technologies in the pipeline [27][28] - The company is optimistic about the Medicare coverage for EsoGuard, which is seen as a significant milestone for Lucid [10][11] Other Important Information - The company has secured financing to support the development and FDA submission of Veris's implantable device, with a submission planned for 2026 [12][18] - The company is focused on building a clinical support team to enhance the efficiency of its platform and provide value-added services to commercial partners [16][42] Q&A Session Summary Question: Status of the implantable monitor development - Management confirmed that the development is progressing well with a new manufacturing partner, and the clinical requirements are modest, primarily involving a skin study [33][34][38] Question: Commercialization conversations with other cancer centers - Management indicated that they plan to start commercialization discussions with other centers in the first quarter after gaining experience with OSU [40][41] Question: Exclusivity and timing of the endoscopic imaging technology agreement - Management stated that a definitive license agreement is expected soon, and the technology will be developed within a separate subsidiary of PAVmed [46][48]

Financial Data and Key Metrics Changes - The company reported a GAAP net loss of $6 million for the third quarter, which includes a non-cash loss of $4.4 million due to changes in the fair value of equity investments [23][24] - Non-GAAP loss for the quarter was $446,000, primarily reflecting incremental contractor development costs for the Veris implantable device [24][25] - Cash burn rate for the third quarter was $900,000, which included approximately $500,000 in outside contractor development costs for Veris [20][24] Business Line Data and Key Metrics Changes - Lucid's revenue for the quarter was $1.2 million, with test volume exceeding 2,800, consistent with the target range of 2,500-3,000 tests [10][11] - Veris launched the commercial phase of its strategic partnership with OSU, targeting 1,000 patients in the first year for enrollment in a registry [12][14] Market Data and Key Metrics Changes - The Medicare contractor meeting in September was successful, with experts endorsing Medicare coverage for EsoGuard, marking a significant milestone for Lucid [10][11] - PAVmed remains the largest shareholder of Lucid, owning approximately 23% of the common shares outstanding, although it no longer has voting control [21] Company Strategy and Development Direction - The company aims to stabilize its corporate structure and balance sheet, with plans to operate as a diversified commercial life sciences company with multiple independently financed subsidiaries [5][6] - PAVmed is pursuing additional technologies, including a partnership with Duke University for an endoscopic imaging technology for esophageal precancer [8][46] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about the company's positioning to capitalize on Lucid's market opportunities and the potential for Medicare coverage [9][10] - The company is focused on expanding its commercial offerings and enhancing its value proposition through clinical support services and AI-based clinical decision tools [17][43] Other Important Information - The company has restructured its debt, exchanging about 80% of its outstanding debt for new Series C preferred equity [19] - The development of the Veris implantable device is progressing well, with a clear regulatory pathway established for FDA submission [34][38] Q&A Session Summary Question: Status of the implantable monitor development - Management confirmed that the development work has relaunched with a new manufacturing partner and that the clinical requirements for FDA submission are modest [33][34] Question: Timing for commercialization conversations with other cancer centers - Management indicated that they plan to start expanding commercial activities to other centers in the first quarter after gaining experience with OSU [40][41] Question: Exclusivity and timing of the endoscopic imaging technology agreement - Management stated that a definitive license agreement is expected soon, and the technology will be developed within a separate subsidiary of PAVmed [45][46]