BILLERICA, Mass.--(BUSINESS WIRE)--Quanterix Corporation (NASDAQ: QTRX), a company transforming healthcare by accelerating biomarker breakthroughs from discovery to diagnostics, today announced publication of a landmark study in the high impact journal JAMA Network Open, https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2842215. The study, led by researchers at Amsterdam UMC, followed a cohort of nearly 300 individuals for up to 15 years. The findings demonstrated that while individu. ...

Market Performance - U.S. stocks showed positive movement, with the Nasdaq Composite gaining approximately 150 points on Friday [1] - The Dow increased by 0.38% to 49,453.05, while the NASDAQ rose by 0.66% to 23,635.11, and the S&P 500 climbed 0.48% to 6,954.85 [1] - European shares also experienced gains, with the eurozone's STOXX 600 up by 0.91% and other major indices like Spain's IBEX 35 and London's FTSE 100 also rising [6] - Asian markets closed mostly higher, with Japan's Nikkei 225 gaining 1.61% and China's Shanghai Composite rising 0.92% [7] Sector Performance - Utilities sector shares increased by 1.5% on Friday, while health care stocks saw a decline of 0.5% [1] Commodity Prices - Oil prices rose by 2.7% to $59.34, gold increased by 1.2% to $4,514.50, silver surged by 6.3% to $79.895, and copper rose by 2% to $5.9150 [5] Company News - Rich Sparkle Holdings Ltd shares surged 115% to $52.00 after signing a $39 million offering of 3 million ordinary shares at $13 per share [9] - Quanterix Corp shares increased by 31% to $8.54 following the appointment of a new CEO [9] - CG Oncology Inc shares rose by 24% to $52.18 after announcing an expedited timeline for clinical trial data [9] - Aquestive Therapeutics Inc shares dropped 40% to $3.72 due to FDA identified deficiencies [9] - Pacira Biosciences Inc shares fell 13% to $22.70 after reporting preliminary FY25 revenue results [9] - Beta Bionics Inc shares decreased by 31% to $21.98 following preliminary fourth-quarter financial results [9] Economic Indicators - Nonfarm payrolls increased by 50,000 in December, slightly below expectations [10] - The unemployment rate decreased to 4.4%, below expectations of 4.5% [10] - Average hourly earnings rose by 0.3%, matching forecasts [10] - Housing starts declined by 4.6% to an annualized rate of 1.246 million units [10] - Building permits fell by 0.2% to an annualized rate of 1.412 million [10] - The University of Michigan's consumer sentiment index rose to 54.0, the highest since September 2025 [2][10]

Market Performance - U.S. stocks showed positive movement, with the Nasdaq Composite gaining approximately 150 points on Friday [1] - The Dow increased by 0.38% to 49,453.05, while the NASDAQ rose by 0.66% to 23,635.11, and the S&P 500 climbed 0.48% to 6,954.85 [1] - Utilities sector shares increased by 1.5%, while health care stocks experienced a decline of 0.5% [1] Commodity Prices - Oil prices rose by 2.7% to $59.34, gold increased by 1.2% to $4,514.50, silver surged by 6.3% to $79.895, and copper rose by 2% to $5.9150 [5] European Market Trends - European shares were generally higher, with the eurozone's STOXX 600 gaining 0.91%, Spain's IBEX 35 Index rising 0.01%, London's FTSE 100 increasing by 0.85%, Germany's DAX up by 0.43%, and France's CAC 40 rising by 1.23% [6] Asian Market Trends - Asian markets closed mostly higher, with Japan's Nikkei 225 gaining 1.61%, Hong Kong's Hang Seng Index up by 0.32%, China's Shanghai Composite rising by 0.92%, while India's BSE Sensex fell by 0.72% [7] Company-Specific Movements - Rich Sparkle Holdings Ltd saw its shares increase by 115% to $52.00 after signing a $39 million offering of 3 million ordinary shares at $13 per share [9] - Quanterix Corp shares surged by 31% to $8.54 following the appointment of Everett Cunningham as President and CEO [9] - CG Oncology Inc shares rose by 24% to $52.18 after announcing an expedited timeline for clinical trial data [9] - Aquestive Therapeutics Inc shares dropped by 40% to $3.72 due to an FDA letter identifying deficiencies [9] - Pacira Biosciences Inc shares fell by 13% to $22.70 after reporting preliminary FY25 revenue results [9] - Beta Bionics Inc shares decreased by 31% to $21.98 following preliminary fourth-quarter financial results [9] Economic Indicators - Nonfarm payrolls increased by 50,000 in December, slightly below expectations of 60,000 [10] - The unemployment rate decreased from 4.5% in November to 4.4%, below expectations [10] - Average hourly earnings rose by 0.3%, matching forecasts [10] - Housing starts declined by 4.6% to an annualized rate of 1.246 million units, while building permits fell by 0.2% to an annualized rate of 1.412 million [10] - The University of Michigan's consumer sentiment index rose to 54.0 in January, the highest since September 2025 [10]

Core Insights - U.S. stocks experienced an upward trend, with the Dow Jones index increasing by approximately 200 points on Friday [1] Company Highlights - CG Oncology Inc (NASDAQ:CGON) saw its shares rise by 21.8% to $51.05 after announcing an expedited timeline for topline data from the Phase 3 PIVOT-006 clinical trial, now expected in the first half of 2026 [1][2] - Rich Sparkle Holdings Ltd (NASDAQ:ANPA) surged 113.6% to $51.70 following a $39 million offering of 3 million ordinary shares at $13 per share [3] - NovaBay Pharmaceuticals Inc (NYSE:NBY) increased by 34.4% to $12.81 [3] - Quanterix Corp (NASDAQ:QTRX) gained 29.3% to $8.42 after naming Everett Cunningham as President and CEO, effective January 19 [3] - MoonLake Immunotherapeutics (NASDAQ:MLTX) rose 21.7% to $17.45 after receiving FDA feedback on its clinical evidence strategy for Sonelokimab in Hidradenitis Suppurativa [3] - Enliven Therapeutics Inc (NASDAQ:ELVN) increased by 21.5% to $28.24, sharing positive initial data from its Phase 1b ENABLE trial for ELVN-001 in chronic myeloid leukemia [3] - Aeva Technologies Inc (NASDAQ:AEVA) surged 21.2% to $20.47 [3] - Loandepot Inc (NYSE:LDI) rose 20.1% to $2.93 [3] - ASP Isotopes Inc (NASDAQ:ASPI) increased by 19.7% to $7.71 [3] - Allogene Therapeutics Inc (NASDAQ:ALLO) gained 19.5% to $1.78 [3] - Opendoor Technologies Inc (NASDAQ:OPEN) rose 19.2% to $7.67 following a new housing market proposal by President Donald Trump [3] - Liquidia Corp (NASDAQ:LQDA) jumped 14% to $36.22 after announcing preliminary full-year 2025 YUTREPIA net sales [3] - Vistra Corp (NYSE:VST) gained 13.1% to $170.34 after entering into 20-year power purchase agreements for zero-carbon nuclear energy to support Meta's operations [3] - Oklo Inc (NYSE:OKLO) rose 12.6% to $109.95 after announcing an agreement with Meta for a 1.2 gigawatt power campus [3] - Applied Digital Corp (NASDAQ:APLD) surged 11.8% to $35.72, reporting strong second-quarter results and advanced talks with a new hyperscaler tenant [3] - AST SpaceMobile Inc (NASDAQ:ASTS) gained 10% to $99.65 [3] - SanDisk Corp (NASDAQ:SNDK) increased by 9.6% to $366.93 [3] - Mirion Technologies Inc (NYSE:MIR) rose 9.5% to $26.56 [3] - TTM Technologies Inc (NASDAQ:TTMI) gained 9.1% to $72.94 [3] - SoundHound AI Inc (NASDAQ:SOUN) rose 8.5% to $11.96 [3] - Kratos Defense & Security Solutions Inc (NASDAQ:KTOS) gained 8.3% to $112.64, with B. Riley Securities maintaining a Buy rating and raising the price target from $105 to $128 [3]

Compensation and Benefits - The annual base salary for the new President and CEO is set at $750,000, subject to periodic review and potential upward adjustment [5]. - The target annual performance bonus is up to 100% of the base salary, contingent on achieving specific metrics and goals established by the Company [6]. - A sign-on cash payment of $600,000 will be provided within 30 days following the start date, with repayment conditions specified [8]. - The new executive will receive 1,070,000 Time-Based RSUs and 813,750 Performance-Based RSUs, with vesting schedules based on stock price performance [9]. - Performance-Based RSUs will vest based on the volume weighted average price (VWAP) of the Company's stock reaching $10, $15, and $20 per share over specified periods [9]. Termination and Severance - In the event of termination without Cause, the executive will receive salary continuation for 12 months, an amount equal to the target bonus, and health benefits continuation [14][15][16]. - If termination occurs within a Change-in-Control period, the severance benefits will extend to 24 months, with additional health benefits and bonus payments [18][19]. - The employment is classified as "at-will," allowing either party to terminate the employment at any time for any reason [13]. - The definition of "Change-in-Control" includes events such as a person acquiring 50% or more of the company's voting securities, changes in the Board of Directors, mergers, or the sale of substantially all assets [28]. - "Good Reason" conditions include material reductions in authority, duties, or salary exceeding 10%, and significant changes in geographic work location [29][30]. Payment and Tax Considerations - Payments under the agreement may be subject to "parachute payment" rules under Section 280G, which could trigger excise taxes [32]. - If a payment is deemed an "Overpayment" or "Underpayment," the company must repay or pay the difference with interest at the applicable federal rate [35]. - The agreement aims to comply with Section 409A of the Internal Revenue Code, ensuring that payments are structured to avoid penalties [36]. - Payments classified as "non-qualified deferred compensation" will only be payable upon separation from service [37]. - If the employee is classified as a "specified employee," payments may be delayed for six months post-separation to comply with Section 409A [38]. - The company is not liable for any tax consequences related to payments under the agreement, including those under Section 409A [41][42]. Miscellaneous Provisions - The employee is not required to seek other employment to mitigate amounts payable under the agreement [43]. - Upon termination, the employee must return all company property and confidential information [44]. - The agreement constitutes the entire understanding between the parties and supersedes all prior agreements [50]. - Any portion declared illegal or unenforceable will not affect the remainder of the agreement [50]. - The agreement's provisions will survive termination to effectuate its terms [50]. - Amendments to the agreement require a written instrument signed by both parties [50]. - The company may assign its rights under the agreement without consent, but the employee cannot assign their interests without prior written consent [50]. - The agreement may be executed in counterparts, which together constitute one document [51]. - The employee acknowledges the opportunity to seek independent legal counsel before signing [51]. - The agreement is signed by the Executive Chair of Quanterix Corporation [52]. - The employee's acceptance is confirmed by their signature on the agreement [52].

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Core Insights - The article discusses the challenges in evaluating Quanterix (QTRX) shares following its acquisition of Akoya Biosciences, which introduced skepticism and losses into the company [1]. Group 1: Company Overview - Quanterix (QTRX) has faced difficulties in share evaluation post-acquisition of Akoya Biosciences, indicating potential concerns regarding its financial health and market perception [1]. Group 2: Investment Opportunities - The service "Value in Corporate Events" aims to provide actionable insights on major corporate events such as earnings reports, M&A, and IPOs, focusing on identifying the best investment opportunities [1].

Core Insights - Quanterix Corporation announced leadership and governance changes to support its next growth phase, including the appointment of Garret Hampton and Alan Sachs to the Board of Directors [1][2][5] - Bill Donnelly has been appointed as Executive Chair, while Jeffrey Elliott takes on the role of Lead Independent Director [2][3] - The Board now consists of nine members, with seven being independent, following the departure of Paul Meister and David Walt [4][6] Leadership Changes - Garret Hampton, Ph.D., previously President of Clinical Next Generation Sequencing and Oncology at Thermo Fisher Scientific, brings over 35 years of experience in life sciences and diagnostics [7] - Alan Sachs, M.D., Ph.D., former Chief Medical Officer and Chief Scientific Officer at Thermo Fisher Scientific, has over two decades of experience in molecular diagnostics [8] - Bill Donnelly, now Executive Chair, will collaborate closely with the leadership team to support strategic initiatives, including the expansion of biomarker offerings and the launch of LucentAD Complete for Alzheimer's diagnosis [3][5] Strategic Focus - The leadership changes are aimed at advancing Quanterix's strategic initiatives, particularly in expanding its blood- and tissue-based biomarker menu and leveraging synergies from the Akoya acquisition [3][6] - The company is entering a new era post-Akoya acquisition, with confidence in delivering value to shareholders and stakeholders [6]

Core Insights - Quanterix Corporation announced a landmark study validating a dual biomarker approach using GFAP and NfL for monitoring Multiple Sclerosis (MS), published in the journal 'Brain' [1][2] Group 1: Study Findings - The study led by Professor Jens Kuhle demonstrated that elevated serum GFAP levels are significantly associated with an increased risk of Progression Independent of Relapse Activity (PIRA), which is a critical unmet need in MS [2] - Serum NfL was confirmed as the gold standard for predicting future relapses and monitoring acute disease activity, providing a comprehensive view of a patient's status [2][4] - The combination of GFAP and NfL allows for monitoring both acute inflammatory activity and chronic disease progression, enhancing personalized patient management [2][4] Group 2: Technological Advancements - Extensive Simoa-based normative reference databases for GFAP and NfL were established, generated from thousands of individuals, enabling meaningful clinical interpretation of test results [3] - The use of a free online tool for interpreting individual patient results based on age, sex, and BMI allows clinicians to accurately assess biomarker status and progression risk [3] - Quanterix's Simoa technology enables highly sensitive assays in a single multiplexed test, creating a unique ecosystem for precision medicine in MS [5] Group 3: Implications for Treatment - The study suggests that GFAP levels decrease under fingolimod treatment, indicating a potential novel mechanism of action for this drug class, which could open new avenues for drug development and monitoring [5] - The integration of GFAP and NfL into clinical practice is expected to materially advance the management of MS patients, offering a best-in-class approach [5]

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