RAD 402 is a humanized IgG1 internalized by prostate cells, binding KLK3 with high affinity Tb-161 antitumor activity driven by the dual emission of beta particles and Auger electrons SYDNEY, Nov. 18, 2025 (GLOBE NEWSWIRE) -- Radiopharm Theranostics (ASX:RAD, “Radiopharm” or the “Company”), a clinical-stage biopharmaceutical company focused on developing innovative oncology radiopharmaceuticals for areas of high unmet medical need, today announced that it has been granted Bellberry Human Research Ethics Co ...

Early patient data from Phase 2b clinical trial showed significant and selective tumor uptake in brain metastases compared to MRI Phase 2b clinical trial expected to complete enrollment and have topline data in 1H26 SYDNEY, Nov. 17, 2025 (GLOBE NEWSWIRE) -- Radiopharm Theranostics (ASX:RAD, “Radiopharm” or the “Company”), a clinical-stage biopharmaceutical company focused on developing innovative oncology radiopharmaceuticals for areas of high unmet medical need, today announced that the Phase 2b trial eval ...

Data Safety Monitoring Committee approves advancing to a higher dose of 90mCi The first two Cohorts’ patients show tumor uptake and a favourable safety profile SYDNEY, Nov. 12, 2025 (GLOBE NEWSWIRE) -- Radiopharm Theranostics (ASX: RAD, Nasdaq: RADX, “Radiopharm” or the “Company”), a clinical-stage biopharmaceutical company focused on developing innovative oncology radiopharmaceuticals for areas of high unmet medical need, today announced the completion of enrollment for the second cohort of patients in the ...

Core Insights - Radiopharm Theranostics is advancing its clinical programs with promising early data from multiple trials, indicating strong potential for its radiopharmaceutical pipeline [1][2][3] Clinical Trials and Data - Preliminary data from the Phase 2b trial of RAD 101 shows uptake in brain metastases from solid tumors, with topline results expected by H1 2026 [1][6] - The Phase 1 trial of RAD 202 (HER2) has shown higher than expected tumor uptake, with data from the second cohort anticipated by year-end 2025 [1][10] - RAD 204 (PD-L1) has demonstrated promising tumor uptake and stable disease in two out of three patients at the first dose level [5][11] - RAD 301 is being evaluated in a Phase 1 imaging trial for pancreatic cancer, with initial data supporting a move to a Phase 2 trial [8][12] Regulatory and Designation Updates - RAD 101 has received FDA Fast Track Designation to expedite its review process for patients with cerebral metastases [3] - RAD 301 has received Orphan Drug Designation from the FDA, highlighting its potential in treating pancreatic ductal adenocarcinoma [8] Company Strategy and Future Plans - The company plans to initiate Phase 1 trials for RV01 and RAD402 by year-end 2025, expanding its clinical portfolio to include four therapeutic candidates and two imaging agents [2] - The strategic execution of the company remains strong, with a focus on advancing multiple trials and achieving significant milestones [2][9]

Core Points - Radiopharm Theranostics Limited has successfully raised approximately A$35 million through a private placement of new shares at A$0.03 per share, with significant participation from institutional investors including Lantheus Holdings, Inc. [1][5][6] - The company will also conduct a Share Purchase Plan (SPP) to raise an additional A$5 million for existing eligible shareholders, maintaining the same terms as the placement [3][6]. Placement Details - The placement involves the issuance of approximately 1,167 million new fully paid ordinary shares, with Lantheus investing A$7.6 million, increasing its shareholding to 14.5% [5][6]. - Each placement subscriber will receive one free attaching option for every share subscribed, with an exercise price of A$0.039 and an expiration date of October 31, 2027 [2][10]. Use of Funds - The funds raised will be allocated as follows: A$6 million for drug manufacturing, A$34 million for clinical trials, and A$19 million for administration and working capital, extending the funding runway into 2027 [4][7][6]. Shareholder Approval - The second tranche of the placement, amounting to A$22.5 million, will require shareholder approval at an upcoming Extraordinary General Meeting (EGM) anticipated in early December 2025 [9][10].

Core Insights - CVS Pharmacy has successfully acquired select assets from Rite Aid, now serving over 9 million former Rite Aid and Bartell Drugs patients [1][2] - The acquisition includes 63 former Rite Aid and Bartell Drugs stores and the prescription files of 626 pharmacies across 15 states [2][4] - CVS Health has completed the conversion of these stores and is actively operating them [3] CVS Pharmacy's Strategy - The company aims to expand access to pharmacy care and enhance its retail presence in local communities [4] - CVS has distributed prescription files to nearby CVS locations, hired over 3,500 former Rite Aid employees, and invested in existing CVS locations for better service [4] Market Context - Rite Aid filed for Chapter 11 bankruptcy in May, following a previous restructuring that closed around 850 stores [5] - The company is in the process of selling its assets, with CVS, Walgreens, Albertsons, Kroger, and Giant Eagle among the bidders for its prescription files [5] Financial Performance - In the second quarter, CVS reported an 18% increase in same-store pharmacy sales, with prescription volumes up by 6% and retail script share reaching 27.8%, partly due to the closure of Rite Aid stores [6]

Core Insights - CVS Pharmacy has completed the acquisition of select Rite Aid and Bartell Drugs assets, enhancing its pharmacy services in the Pacific Northwest and serving millions of customers [1][2]. Expansion across the Pacific Northwest - CVS now operates 63 former Rite Aid and Bartell Drugs stores in Idaho, Oregon, and Washington [2]. - The company has acquired prescription files from 626 former Rite Aid and Bartell Drugs pharmacies across 15 states, allowing CVS to serve over nine million patients [2]. Recruitment and Investment to Support Pharmacy Operations - CVS has hired more than 3,500 former employees from Rite Aid and Bartell Drugs to maintain service standards and ensure timely prescription support [4]. - Targeted investments have been made in existing pharmacy locations to improve staff scheduling, recruitment, and training [4]. Transaction Finalised Following Bankruptcy Court Approval - The acquisition was approved by the US Bankruptcy Court for the District of New Jersey in May 2025, and the entire transaction was completed in under four months [6]. - The final store acquisitions were concluded on September 30, with locations in Bend, Oregon, and Bainbridge Island, Washington [6]. Key Factors in Acquisition Decisions - CVS prioritized convenience and access to essential prescriptions when selecting Rite Aid locations and prescription files for acquisition [7]. - Most CVS stores receiving transferred prescription files are within three miles of existing Rite Aid branches, with nearly half within one mile, minimizing disruption for affected patients and communities [7].

Core Insights - CVS Health has completed the acquisition of 63 Rite Aid stores in Idaho, Oregon, and Washington, along with prescription files across 15 states, serving over 9 million customers [2][3] - The acquisition follows Rite Aid's bankruptcy filing earlier this year, marking its second bankruptcy in less than two years [3] - By acquiring prescription files, CVS and other pharmacy chains avoided taking on additional debt from physical store locations during the bankruptcy proceedings [4] Company Operations - CVS is now operating 63 former Rite Aid and Bartell Drugs locations and has acquired prescription files from 626 former Rite Aid and Bartell Drugs pharmacies across 15 states [5] - The company has hired over 3,500 former Rite Aid and Bartell Drug employees as part of the acquisition and store conversions [5] Strategic Goals - CVS Health aims to expand access to pharmacy care and grow its retail footprint in local communities through this acquisition [6] - The company plans to leverage its innovative pharmacy care programs and exclusive store brand products to enhance customer experience for former Rite Aid and Bartell Drugs patients [6]

US pharmacy chain Rite Aid closes final stores https://t.co/iPMCe6W6yY ...

Core Points - Rite Aid has officially closed all its stores following its Chapter 11 bankruptcy filing, marking its second bankruptcy since October 2023 [1][7] - The company faced significant financial challenges exacerbated by changes in the retail and healthcare sectors, with a reported loss of $750 million in the previous fiscal year [2][7] - Rite Aid's website now only provides a service for former customers to find new pharmacies and request pharmacy records [3] Bankruptcy and Store Closures - Rite Aid filed for Chapter 11 bankruptcy in May 2023 and announced the closure of all its stores as part of its bankruptcy plan [1][4] - At its peak, Rite Aid operated thousands of stores, but by May 2023, it had reduced to 1,240 locations across 15 states [6] Transition of Services - The company entered into agreements to transition its pharmacy services and assets to other pharmacy chains, including CVS Pharmacy and Walgreens, ensuring a smooth transfer of customer prescriptions [4] - CEO Matt Schroeder emphasized the importance of maintaining uninterrupted pharmacy services for customers and preserving jobs for associates during the transition [2][4] Asset Sales - Rite Aid auctioned its in-house ice cream brand, Thirty Ice Cream, to Hilrod Holdings for $19.2 million, with the transaction approved by a federal judge [5] - The company had previously owned Thrifty PayLess, Inc., which was part of the assets sold during the bankruptcy process [5] Debt Situation - After emerging from bankruptcy in 2024, Rite Aid was reported to still have $2.5 billion in debt [8]