PAPZIMEOS Approval and Launch - PAPZIMEOS received full FDA approval in 2025 for treating all adults with RRP, regardless of disease severity[10, 14] - PAPZIMEOS is the first and only FDA-approved therapy for adults with RRP, targeting the underlying cause of the disease[16] - The company commenced the commercial US launch of PAPZIMEOS and initiated its commercial manufacturing campaign in 2025[10] - Over 50 accounts, including academic and community settings, have prescribed PAPZIMEOS[33] - The company has seen a rapid increase in unaided brand awareness of PAPZIMEOS across academic and community settings[34] Clinical Data and Efficacy - Clinical data shows a 51% complete response rate with PAPZIMEOS, with durable ongoing complete responses[21] - PAPZIMEOS significantly reduced the number of surgeries required post-treatment, with p<0001[22] - Median duration of follow-up was at 36 months (27-37), and the median duration of complete response has yet to be reached[25] Market Opportunity and Expansion - The prevalence of RRP in the US is approximately 27000 adult patients, suggesting a multi-billion-dollar revenue potential[30] - The prevalence of RRP ex-US is approximately 35000 adults in EU4, UK, and Japan, approximately 50000 adults in the rest of EU and select markets, and approximately 85000 adults in China, suggesting a multi-billion-dollar revenue potential[30] - The company anticipates PAPZIMEOS regulatory expansion to the EU and Japan[37] Financials and Future Milestones - The company secured up to $125 million in non-dilutive funding to fortify its balance sheet[10] - The company aims to achieve positive cash flow in 2026 by continuing execution and expansion to maximize the PAPZIMEOS market opportunity[37]

Company Overview - Savara is focused on building a world-class experienced orphan rare disease company with a team that has extensive experience in the field [3] - The company operates as a single-asset entity with one late-stage product, MOLBREEVI, which is a novel inhaled biologic [3] Product Development - Savara has submitted a Biologics License Application (BLA) in the U.S. for MOLBREEVI's application for use in autoimmune conditions [3]

This article looks at the 14 Best Booming Stocks to Buy Right Now.The S&P 500 registered gains of 16% in 2025, marking the third successive year of double-digit returns after the broad market index rallied 24% in 2023 and then 23% in 2024.Total gains over the past three years have amounted to approximately 80%, the strongest run over a three-year win streak since the index surged 90% between 2019 and 2021.A Financial Times survey of major investment banks in December forecast a 10% gain in the S&P 500 in 20 ...

Company Overview - Mesa Labs is a diversified tools company focusing on mission-critical quality controls for regulated markets, particularly in the biopharmaceutical sector [2][4] - The company engages in the drug life cycle from the development phase, providing clinical trial support and ensuring drug integrity throughout bioproduction and into the healthcare system [2][4] Mission and Purpose - The company's purpose is human-centric, emphasizing the protection of vulnerable populations by ensuring that drugs are manufactured correctly and are of the highest quality before reaching patients [3] Market Focus - Mesa Labs targets highly regulated end markets, which provide a natural stickiness to their business model, particularly through consumable and recurring revenue streams [4]

Company Overview - Disc Medicine has been publicly listed for approximately three years and has experienced a productive journey during this period [3] - The company is on the verge of approval for its lead program and has a robust pipeline of additional programs progressing well [3] Clinical Programs - The presentation will cover three investigational agents: bitopertin, DISC-0974, and DISC-3405, which are not yet approved as therapies anywhere in the world [4] - The company aims to provide updates on the progress towards approval for its lead program and discuss launch strategies [5]

Biotech and healthcare names were among the notable movers in Wednesday's after-hours trading session, with several small-cap companies posting strong gains on the back of corporate updates and investor momentum.Plus Therapeutics, Inc. (PSTV) surged 8.40% to close at $0.31 after announcing the pricing of its underwritten public offering. The company is issuing 39,473,684 units, each consisting of one share of common stock and one warrant, at $0.38 per unit. Gross proceeds are expected to total approximatel ...

Company Overview - Liquidia is a biopharmaceutical company focused on improving inhaled drug delivery through proprietary formulations, particularly in the prostacyclin class of therapeutics [4]. Performance Highlights - The company had a spectacular year in 2025, indicating strong performance and growth [2]. Leadership Team - The presentation included key members of the leadership team, such as the CEO Roger Jeffs, CFO Michael Kaseta, and other executives, highlighting the collaborative effort in driving the company's vision [3].

Core Insights - Ascentage Pharma Group International presented its achievements in 2025 and outlined its global innovation strategy for 2026 at the J.P. Morgan Healthcare Conference [1][2] Company Overview - Ascentage Pharma is a global, commercial stage biopharmaceutical company focused on developing novel therapies for unmet medical needs in cancer [9] - The company has a diverse pipeline that includes inhibitors targeting key proteins in the apoptotic pathway and next-generation kinase inhibitors [9] Milestone Achievements - In 2025, Ascentage Pharma accelerated its global expansion, advancing product commercialization, clinical development, and pipeline innovation [2] - The company has established a strong foundation for sustained growth through its innovative engine in hematologic malignancies and solid tumors [2] Product Development - The two core products, Olverembatinib (a third-generation BCR-ABL inhibitor) and Lisaftoclax (a Bcl-2 inhibitor), are key growth drivers for 2026 [3] - Both products have shown significant progress in 2025 and are expected to generate a "dual-engine" effect for future growth [3] Clinical Studies and Innovations - Ascentage Pharma has made advancements in multiple clinical studies for its key drug candidates, presenting data at international academic congresses [4] - The company received IND clearance from the U.S. FDA for APG-3288, a novel BTK degrader, marking a significant step in targeted degradation [4][5] Pipeline Progress - The company is advancing several key clinical programs, including APG-5918 (EED inhibitor) and APG-2449 (FAK/ALK/ROS1 inhibitor), which are in various stages of clinical trials [6][7] - Multiple global registrational Phase III trials are progressing rapidly for its key products [5] Future Outlook - Potential milestones for 2026 include ongoing investigations of Olverembatinib, Lisaftoclax, and other pipeline candidates, which have not yet received FDA approval [8] - The company aims to continue its growth in commercial sales and expand patient accessibility across hospitals in China [12]

©2026 LIQUIDIA CORPORATION ALL RIGHTS RESERVED 2 Corporate Overview J.P. Morgan Healthcare Conference 2026 January 14, 2026 ©2026 LIQUIDIA CORPORATION ALL RIGHTS RESERVED Forward-looking statements This presentation includes, and our response to questions may include, forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 ("PSLRA"). All statements contained in this presentation other than statements of historical facts, including statements regarding our future ...

Core Insights - Samsung Epis Holdings is entering a significant phase in 2026, announcing six new candidates in its biosimilar pipeline, aiming for a total of 20 biosimilars by 2030 [1][4] - The company has received IND clearance for its first novel therapeutic candidate, SBE303, and plans to advance its clinical program this year [1][4] - Samsung Bioepis is expanding its portfolio beyond biosimilars, focusing on antibody-drug conjugates (ADCs) to address unmet medical needs [1][4] Biosimilar Pipeline - Samsung Bioepis currently has 11 biosimilars approved and launched in over 40 countries, covering 10 unique biological molecules [4] - The new biosimilar candidates include dupilumab, guselkumab, ixekizumab, fam-trastuzumab deruxtecan-nxki, vedolizumab, and ocrelizumab [4][6] - The company has launched several biosimilars, including adalimumab (Humira), etanercept (Enbrel), infliximab (Remicade), trastuzumab (Herceptin), and bevacizumab (Avastin) [3][5] Novel Therapeutics Development - SBE303 is Samsung Bioepis' first novel ADC targeting Nectin-4, with a Phase 1 clinical trial set to begin this year [4] - The company aims to introduce one novel therapeutic candidate into clinical studies each year [4] - Epis NexLab, a new subsidiary, is focused on developing a peptide-based drug delivery platform [4][9] Company Overview - Samsung Epis Holdings is dedicated to biopharmaceuticals and biotechnology, aiming to maximize corporate and shareholder value through R&D and strategic investments [7] - Samsung Bioepis, established in 2012, focuses on making healthcare accessible through innovative product development across various therapeutic areas [8] - Epis NexLab, established in 2025, is committed to driving innovation in next-generation biotechnology platforms [9]