Hong Kong-based Harbour BioMed announced on Sunday an update and advancement of its global strategic collaboration with AstraZeneca Plc (NASDAQ:AZN) , initially established in March 2025. • AZN is in positive territory. Get the market research here.Harbour BioMed is a biopharmaceutical company focused on the discovery and development of antibody therapeutics in immunology and oncology.The collaboration aims to discover and develop next-generation biotherapeutics, including antibody-drug conjugates and T cel ...

Summary of MBX Biosciences Conference Call Company Overview - **Company**: MBX Biosciences - **Focus**: Building a leading biopharmaceutical company focused on endocrine and metabolic diseases with three clinical-stage programs aimed at multi-billion dollar markets [2][44] Key Programs and Developments - **Canvuparatide**: - Recently released outstanding phase two data for a once-weekly PTH replacement therapy in hypoparathyroidism [2] - Anticipated end of phase two meetings with FDA and EMA in Q1 2024 [3] - Phase three registration study initiation expected in Q3 2024 [3] - **MBX 4291**: - A GLP-1 GIP coagonist prodrug with a potential once-monthly dosing schedule for obesity [3][4] - 12-week MAD results expected in Q4 2024, aiming to demonstrate better tolerability and weight loss compared to competitors [5][10] - Unique PK profile with a flat peak-to-trough ratio observed in non-human primate studies, suggesting improved tolerability [9][10] Market Position and Strategy - **Obesity Market**: - The obesity candidate MBX 4291 is positioned to leverage the growing demand for once-monthly dosing in the obesity treatment landscape [4][5] - The company aims to address adherence challenges seen with current incretin therapies, which have high discontinuation rates [17][18] - **Competitive Landscape**: - The company is focused on differentiating its products through better tolerability and convenience, which are critical for chronic use [17][18] - Market research indicates that a well-tolerated drug with comparable weight loss could be considered best in class [18][37] Financial and Operational Outlook - **Funding**: - The company has secured funding into 2029, supporting ongoing clinical trials and pre-commercial activities [3][46] - **Regulatory Strategy**: - Plans to engage with regulatory agencies to discuss trial designs and endpoints, including stratification for PTH levels and urine calcium changes [31][32] Other Programs - **Imapextide and PBH Program**: - Phase two study focusing on pharmacodynamic effects, aiming to increase glucose nadir while reducing insulin peak [40] - Safety profile indicates benign nature of injection site reactions, which are not expected to impede prescribing if approved [41][42] Underappreciated Aspects - **Platform Technology**: - The potential of MBX's clinically proven platform technology for gradual controlled release is highlighted as a key differentiator [44][46] - **Pipeline Value**: - The company emphasizes the value inflection points across its pipeline programs, positioning itself favorably in the market [46] Conclusion - MBX Biosciences is poised for significant developments in 2024, with multiple catalysts expected across its pipeline, particularly in obesity and endocrine therapies. The focus on tolerability and convenience in drug administration is central to its strategy in a competitive market.

Live webcast fireside chat on Tuesday, December 2nd at 10:00 AM ETISELIN, N.J., Nov. 24, 2025 (GLOBE NEWSWIRE) -- Outlook Therapeutics, Inc. (Nasdaq: OTLK), a biopharmaceutical company focused on enhancing the standard of care for bevacizumab for the treatment of retina diseases, today announced that Bob Jahr, Chief Executive Officer of Outlook Therapeutics, will participate in a fireside chat at the Piper Sandler 37th Annual Healthcare Conference on Tuesday, December 2, 2025 at 10:00 AM ET. In addition to ...

SAN DIEGO, Nov. 24, 2025 (GLOBE NEWSWIRE) -- Connect Biopharma Holdings Limited (Nasdaq: CNTB) (“Connect Biopharma”, “Connect”, or the “Company”), a clinical-stage biopharmaceutical company focused on transforming care for the treatment of inflammatory diseases, today announced that Company management will participate in a fireside chat at the 8th Annual Evercore Healthcare Conference on Tuesday, December 2nd, 2025 at 10:50 a.m. ET. The live webcast of the presentation may be accessed via the Investors sect ...

Core Insights - Catalyst Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing and commercializing treatments for rare and difficult-to-treat diseases [3] - The company will participate in the Bank of America CNS Therapeutics Virtual Conference on December 8, 2025, at 12:35 PM ET [1][2] Company Overview - Catalyst Pharmaceuticals is committed to improving the lives of patients with rare diseases and has a proven track record of bringing life-changing treatments to market [3] - The company emphasizes accessibility and provides a comprehensive suite of support services to ensure patients receive necessary care [3] - Catalyst has a strong U.S. presence and is exploring strategic opportunities for global expansion [3] - The company was recognized on the Forbes 2025 list as one of America's Most Successful Mid-Cap Companies and on the Deloitte Technology Fast 500™ list as one of North America's Fastest-Growing Companies [3]

TEL AVIV, Israel, Nov. 24, 2025 (GLOBE NEWSWIRE) -- Chemomab Therapeutics Ltd. (Nasdaq: CMMB) (Chemomab), a clinical stage biotechnology company developing innovative therapeutics for fibro-inflammatory diseases with high unmet need, today announced that co-founder and CEO Adi Mor, PhD, will participate in Oppenheimer's Movers in Rare Disease Summit on Thursday, December 11, 2025, at the Sofitel Hotel in New York City. The invitation-only Rare Disease Summit will feature a day of panels, presentations and 1 ...

REDWOOD CITY, Calif., Nov. 24, 2025 (GLOBE NEWSWIRE) -- Soleno Therapeutics, Inc. (“Soleno”) (NASDAQ: SLNO), a biopharmaceutical company developing novel therapeutics for the treatment of rare diseases, today announced that Anish Bhatnagar, M.D., Chief Executive Officer, will participate in a fireside chat at the Piper Sandler 37th Healthcare Conference on Thursday, December 4, 2025, at 9:00 AM Eastern Time. A live audio webcast and replay of the presentation will be available in the Investors section on th ...

Berkeley Heights, New Jersey--(Newsfile Corp. - November 24, 2025) - Kalaris Therapeutics, Inc. (Nasdaq: KLRS) ("Kalaris"), a clinical-stage biopharmaceutical company dedicated to the development and commercialization of treatments for prevalent retinal diseases, today announced that management will present at the upcoming Noble Capital Markets 21st Annual Emerging Growth Equity Conference.Details:Type: Company presentationSpeakers: Matthew Feinsod, Chief Medical Officer Date: Wednesday, December 3, 2025Ti ...

NEW YORK, Nov. 24, 2025 (GLOBE NEWSWIRE) -- LB Pharmaceuticals Inc (“LB Pharmaceuticals” or the “Company”) (Nasdaq: LBRX) today announced that Heather Turner, Chief Executive Officer, will present at the Piper Sandler 37th Annual Healthcare Conference in New York, NY on Wednesday, December 3, 2025, at 9:30 a.m. ET. A live webcast of the presentation will be available on the “Investors” page under the “Events” section of the Company’s website at https://ir.lbpharma.us/investors/events/, where a replay of the ...

CAMBRIDGE, Mass., Nov. 24, 2025 (GLOBE NEWSWIRE) -- Akebia Therapeutics®, Inc. (Nasdaq: AKBA), a biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease, today announced that members of its executive team will participate in a Fireside Chat at the Piper Sandler 37th Annual Healthcare Conference on Tuesday, December 2 at 4:30 PM EST. A webcast of the presentation can be accessed through the “Investors” section of Akebia’s website at https://ir.akebia.com following ...