Serina Therapeutics, Inc. Tribe Public’s Webinar Event Meet with Serina’s CEO Steven A. LedgerParkinson's disease is a progressive neurological disorder that primarily affects movementContinuous dopaminergic stimulation (CDS) has been shown to reduce the severity of motor complications (dyskinesia) in advanced Parkinson’s patientsDiscussion of the Serina IND candidate’s target product profile versus the current standard of care in providing CDS HUNTSVILLE, AL, Dec. 16, 2024 (GLOBE NEWSWIRE) -- Serina Th ...

HUNTSVILLE, AL, Dec. 11, 2024 (GLOBE NEWSWIRE) -- Serina Therapeutics, Inc. (“Serina”) (NYSE American: SER), a clinical-stage biotechnology company developing its proprietary POZ Platform™ drug delivery technology, announced that Serina Therapeutics' Chief Development Officer, Randall Moreadith, MD, PhD, will be presenting today at the 3rd Annual LNP Immunogenicity & Toxicity Summit in Boston, MA. Entitled "Overcoming Anti-PEG Antibody Responses – A Novel PEOZ-lipid That Fails to Elicit an Immune Response t ...

HUNTSVILLE, Dec. 02, 2024 (GLOBE NEWSWIRE) -- Serina Therapeutics, Inc. (“Serina”) (NYSE American: SER), a clinical-stage biotechnology company, today announced a $10 million equity financing with strategic shareholder JuvVentures (UK) Limited. The transaction provides Serina with funding to continue advancing SER-252 (POZ-apomorphine), enabled by its proprietary POZ Platform™ drug optimization technology, into a Phase 1 clinical trial in advanced Parkinson's disease patients in the second half of 2025. Und ...

Revenue and Financial Performance - Revenues for Q3 2024 were $14 thousand, a decrease from $29 thousand in Q3 2023[3] - Total revenues for September 2024 were $14 million, a decrease from $29 million in September 2023[22] Operating Expenses - Operating expenses for Q3 2024 increased to $5.3 million from $1.5 million in Q3 2023[3] - General and administrative expenses for Q3 2024 increased to $2.9 million from $0.9 million in Q3 2023[5] - Net loss from operations was $(5.312) million in September 2024, compared to $(1.463) million in September 2023[22] Research and Development - Research and development expenses for Q3 2024 rose to $2.4 million, up from $0.6 million in Q3 2023[4] - Research and development expenses increased to $2.415 million in September 2024 from $603 thousand in September 2023[22] Net Income and Loss - Net income for Q3 2024 was $1.4 million, compared to $1.8 million in Q3 2023[7] - Change in fair value of warrants contributed $6.669 million to other income in September 2024, up from $596 thousand in September 2023[22] Cash and Liquidity - Cash, cash equivalents, and restricted cash totaled $3.2 million as of September 30, 2024[8] - The company anticipates insufficient cash to meet operating needs for the next 12 months, raising substantial doubt about its ability to continue as a going concern[9] - Net cash used in operating activities was $(12.548) million for the period ending September 2024, compared to $(2.597) million in the same period of 2023[23] - Cash, cash equivalents, and restricted cash decreased by $4.384 million to $3.235 million at the end of September 2024[23] Financing Activities - Proceeds from the exercise of Post-Merger Warrants by Juvenescence amounted to $4.988 million in September 2024[23] - Net cash provided by financing activities was $8.181 million in September 2024, down from $10.080 million in September 2023[23] - Issuance of common stock upon conversion of Preferred Stock totaled $36.404 million in September 2024[23] - Merger and issuance of common stock upon consummation of Merger on March 26, 2024, amounted to $961 thousand[23] Assets and Liabilities - Total assets as of September 30, 2024, were $7.435 million, down from $8.968 million at the end of 2023[18] Product Development and Partnerships - SER-252, an investigational apomorphine therapy, is planned for clinical testing in 2025[10] - The POZ Platform™ technology has potential for broad applications, including a non-exclusive license agreement with Pfizer for LNP drug delivery formulations[12]

HUNTSVILLE, Nov. 12, 2024 (GLOBE NEWSWIRE) -- Serina Therapeutics, Inc. (“Serina”) (NYSE American: SER), a clinical-stage biotechnology company advancing its lead IND candidate SER-252 for advanced Parkinson's disease, enabled by its proprietary POZ Platform™ drug optimization technology, today announced its financial results for the third quarter ended September 30, 2024, along with key recent updates. Recent Highlights Partnership and Presentations with Enable Injections: Building on its collaboration wit ...

Table of Contents Title of each class Trading Symbol Name of exchange on which registered Common Stock, par value $0.0001 per share SER NYSE American UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from ___________ to ...

HUNTSVILLE, AL, Nov. 11, 2024 (GLOBE NEWSWIRE) -- Serina Therapeutics, Inc. (“Serina”) (NYSE American: SER), a clinical-stage biotechnology company advancing its lead IND candidate SER-252 for advanced Parkinson's disease, enabled by its proprietary POZ Platform™ drug optimization technology, announced that it has made grants of options to purchase an aggregate of 60,500 shares of Serina’s common stock to three new non-executive employees on November 6, 2024 (each, an “Option Grant”). Each Option Grant has ...

Exhibit 99.1 Serina Therapeutics Reports Second Quarter 2024 Financial Results and Provides Business Highlights HUNTSVILLE, August 9, 2024 (GLOBE NEWSWIRE) — Serina Therapeutics ("Serina") (NYSE American: SER), a clinical-stage biotechnology company developing its proprietary POZ Platform™ drug delivery technology, today reported financial results for the quarter ended June 30, 2024 and provided business highlights. Recent Highlights ● Partnership with Enable Injections. The Company will develop and commerc ...

Financial Performance - Revenues for the three and six months ended June 30, 2024, were not material[204]. - The net loss attributable to Serina for the six months ended June 30, 2024, was $9.8 million, with non-cash items contributing to the difference between net loss and cash used in operating activities[225]. - Other income increased to $9.04 million for Q2 2024, compared to $1.75 million in Q2 2023, primarily due to a $9.3 million gain from the fair value of liability classified Merger Warrants[210]. - For the six months ended June 30, 2024, other expense netted $3.7 million, a change of $8 million from $4.4 million income in the same period in 2023, largely due to a $7 million loss in fair value of Legacy Serina Convertible Notes[211]. Research and Development Expenses - Research and development expenses for Q2 2024 were $1.6 million, a 232.8% increase from $0.5 million in Q2 2023[203]. - For the first half of 2024, research and development expenses totaled $2.7 million, up 207.5% from $0.9 million in the same period of 2023[204]. - The increase in research and development expenses was primarily due to a non-recurring $0.3 million severance expense and increases in salaries and consulting services[205]. - The company expects research and development expenses to increase substantially as it continues to invest in product candidate development and clinical trials[194]. - The company anticipates that research and development expenses will continue to increase as it seeks to advance its product candidates[220]. General and Administrative Expenses - General and administrative expenses for Q2 2024 reached $2.3 million, a 391.1% increase compared to $0.5 million in Q2 2023[203]. - In the first half of 2024, general and administrative expenses were $3.5 million, reflecting a 232.4% increase from $1.1 million in the same period of 2023[204]. - General and administrative expenses increased mainly due to $0.6 million in professional legal and accounting services related to a merger completed on March 26, 2024[208]. - The company anticipates that general and administrative expenses will rise over the next several years to support ongoing research and development and compliance as a public company[200]. Cash Flow and Financing - As of June 30, 2024, the company had $6.1 million in cash and cash equivalents, with $2.9 million drawn from the 2022 Secured Note and $4.99 million received from Juvenescence through Post-Merger Warrants[215]. - The net cash used in operating activities for the six months ended June 30, 2024, was $9.6 million, a significant increase of 509.4% from $1.57 million in the same period in 2023[224]. - Net cash provided by financing activities for the six months ended June 30, 2024, was $8.1 million, primarily from the exercise of Post-Merger Warrants and credit facilities[227]. - The company expects to incur substantial expenditures for product development and will require additional financing to continue operations beyond 2025[221]. Internal Controls and Compliance - The company identified material weaknesses in internal controls over financial reporting, including insufficient qualified accounting staff and reliance on manual reporting processes[232]. - A remediation plan has been initiated to address these weaknesses, involving the engagement of financial operations consultants and the appointment of a new Controller for Legacy Serina[235]. - The company believes that its quarterly report fairly presents its financial condition and results of operations, despite the identified weaknesses[230]. - There were no changes in internal control over financial reporting that materially affected its effectiveness during the reporting period[237]. - The company is committed to ongoing monitoring and enhancement of internal controls as necessary, but acknowledges inherent limitations in their effectiveness[237]. - The material weaknesses will not be remediated until the remediation plan is fully developed and tested for effectiveness[236]. - The company has implemented direct management oversight and the use of legal and accounting professionals to mitigate identified weaknesses[233]. - The company is focused on ensuring the reliability of its financial reporting processes moving forward[230]. Legal Matters - A putative shareholder class action lawsuit was filed against the company related to the Merger Agreement, but was dismissed on March 5, 2024[240]. - The company continues to face potential litigation matters that could materially affect future results of operations and financial position[239].

Exhibit 99.1 Serina Therapeutics Reports First Quarter 2024 Financial Results and Provides Business Highlights HUNTSVILLE, May 14, 2024 (GLOBE NEWSWIRE) — Serina Therapeutics ("Serina") (NYSE American: SER), a clinical-stage biotechnology company developing its proprietary POZ Platform™ drug delivery technology, today reported financial results for the quarter ended March 31, 2024 and provided business highlights. Recent Highlights ● Advancement of SER-252. The Company is advancing its lead drug candidate, ...