Core Viewpoint - Atos Group has signed a binding agreement to sell its South American operations to Semantix, aiming to accelerate its Genesis Transformation plan and refocus on core areas such as AI and cloud solutions [1][4]. Group 1: Transaction Details - The sale involves approximately 2,800 professionals across Brazil, Argentina, Chile, Colombia, Uruguay, and Peru [1]. - The transaction is expected to close in the coming months, pending fulfillment of closing conditions [3]. Group 2: Strategic Implications - This divestment is part of Atos's strategy to return to sustainable growth and improved profitability by concentrating on core geographies and assets [1]. - The acquisition will enhance Semantix's portfolio, making it one of South America's largest AI and Data Enterprise services providers [1][2]. Group 3: Leadership Changes - Nelson Campelo, currently Head of Atos South America, will become the CEO of Semantix, while Leonardo Santos Poça D'água will transition to Executive Chairman [3]. Group 4: Vision and Commitment - The merger is seen as a new growth cycle for both companies, with a focus on delivering enhanced value to clients and society [4]. - Semantix aims to leverage Atos's operational strength to expand its capabilities in regulated sectors such as financial services and healthcare [4].

Core Viewpoint - Acadia Pharmaceuticals Inc. has received FDA approval for DAYBUE® STIX (trofinetide), a new oral solution formulation for treating Rett syndrome in patients aged two years and older [1] Group 1: Product Details - DAYBUE® STIX is a dye- and preservative-free powder formulation of trofinetide [1] - The new formulation is expected to maintain the same efficacy and safety profile as the existing DAYBUE oral solution [1] Group 2: Target Patient Population - The approved treatment is intended for both adult and pediatric patients aged two years and older suffering from Rett syndrome [1]

Core Insights - STIX, a Web3 platform for meme promotions and competitions, achieved 200,000 mints in under 3 days since its launch on August 15, 2024 [1][6] - The platform is a derivative of Stickerly, a major Web2 user-generated content sticker publishing platform with 30 million monthly active users [2] - The STIX mint gained traction through participation from notable crypto communities, leading to increased interest in early access passes [3][4] Company Overview - STIX is connected to Stickerly, which has over 400 million lifetime users and facilitates gamified PvP meme competitions through onchain voting [2] - The STIX mint is part of the ongoing Onchain Summer program on the Base protocol, aimed at promoting crypto adoption among non-crypto native consumers [5] Market Context - The STIX mint's rapid success positions it as one of the largest mints on the Base protocol, surpassing previous top mints during the Onchain Summer program [5][6] - The attention from memecoin and NFT communities is now focused on the upcoming beta tournament and the token generation event (TGE) for the $STIX token [7]

Group 1 - The activation of STIX, co-promoted by Coinbase, will feature a gasless NFT mint on the Ethereum Layer 2 chain Base, serving as access passes to the early beta version of STIX [1] - STIX is a derivative project of Stickerly, a major Web2 user-generated content sticker platform with 30 million monthly active users and over 400 million lifetime users [2] - The STIX team emphasized the strong meme-driven culture and organic growth of user-generated content (UGC) in the Base community as key factors for collaboration [3] Group 2 - STIX will be onboarding Coinbase's Onchain Summer in August, enhancing its visibility and user engagement [4] - The special mint on Base will allow users to access the beta version of STIX, which includes meme competitions utilizing UGC from selected partners [5] - The Web3 version of STIX not only focuses on UGC publishing but also incorporates gamification through popularity competitions, where community voting determines winning memes [6]

Financial Performance - Total revenues for the three-month period ended March 31, 2023, were R$39,679,000, a slight increase from R$39,434,000 in the same period of 2022, representing a growth of 0.62%[4] - Gross profit for the same period increased to R$16,874,000, up from R$12,708,000 in 2022, marking a growth of 32.5%[4] - Operating loss for the three months ended March 31, 2023, was R$46,266,000, compared to a loss of R$43,590,000 in 2022, indicating a deterioration of 6.1%[4] - Net loss for the period was R$47,815,000, compared to R$43,886,000 in the prior year, reflecting an increase in loss of 9.4%[6] - The company reported a comprehensive loss of R$47,979,000 for the three-month period ended March 31, 2023, compared to R$41,951,000 in 2022, an increase of 14.4%[6] - The Group reported a loss before income tax of R$ 50,364 thousand for the period ended March 31, 2023, compared to a loss of R$ 45,788 thousand for the same period in 2022[6]. - The Group reported a loss of R$47,624,000 for the three months ended March 31, 2023, compared to a loss of R$43,824,000 for the same period in 2022[106] Cash and Assets - Cash and cash equivalents decreased to R$231,765,000 as of March 31, 2023, down from R$338,020,000 at the end of 2022, a decline of 31.4%[2] - Total assets decreased to R$596,416,000 as of March 31, 2023, from R$702,541,000 at the end of 2022, a reduction of 15.1%[2] - Total liabilities decreased to R$244,284,000 as of March 31, 2023, from R$281,116,000 at the end of 2022, a decline of 13.1%[2] - The total balance of loans and borrowings decreased to R$ 70,289 thousand as of March 31, 2023, down from R$ 78,671 thousand at the end of 2022[49]. - The Group's total deferred consideration and contingent liabilities decreased to R$ 46,499 thousand as of March 31, 2023, from R$ 63,915 thousand at December 31, 2022[53]. Revenue Breakdown - Revenue from third-party software was R$21,410, remaining stable compared to R$21,411 in the previous year[82] - AI & data analytics services revenue decreased to R$7,875 from R$7,992, a decline of 1.5%[82] - Proprietary software as a service (SaaS) revenue increased to R$10,394 from R$10,028, showing a growth of 3.6%[82] - Total financial revenues for the three-month period were R$10,363, up from R$4,295, marking an increase of 141.5%[89] Expenses and Costs - Total operating costs and expenses for the three-month period were R$85,945, slightly higher than R$83,024 in the same period of 2022[86] - Personnel costs rose to R$36,579 from R$31,257, reflecting an increase of 17.5%[86] Investments and Acquisitions - The company invested R$9,476,000 in the purchase and development of intangible assets during the three months ended March 31, 2023[8] - Semantix completed the acquisition of Elemeno Inc. on February 21, 2023, for a total consideration of R$4,020, which includes R$1,988 paid in cash and R$2,032 payable in installments from 2024 to 2026[33] - The acquisition of Elemeno is expected to enhance Semantix's flagship proprietary platform, the Semantix Data Platform (SDP), particularly its MLOps suite[31] - The Group acquired certain assets, including software from ATSaúde, for R$ 5,430 thousand as part of its strategic plan to expand in the Healthcare & Life Science industry in Brazil[46]. Shareholder Information - The earnings per share for the three-month period ended March 31, 2023, was restated to R$ (0.60), a correction from the previously reported R$ (0.69)[29] - Semantix's total shares outstanding as of March 31, 2023, was reported at 79,099,587 ordinary shares[27] - The weighted average number of common outstanding shares increased to 79,949,000 in 2023 from 62,000,000 in 2022, affecting the calculation of losses per share[106] - Basic and diluted losses per share for the period were R$0.60, improved from R$0.71 in the previous year[106] - The company authorized an increase in its stock repurchase plan from US$5 million to US$10 million on March 29, 2023[72] - As of March 31, 2023, the company held 1,392,474 shares in treasury, with a total amount of R$22,143 spent on repurchased shares during the quarter[73] Financial Management and Risk - The Group's strategy is to maintain a positive net cash position, with capital management policies aimed at sustaining investor and market confidence[101] - Financial risk management focuses on minimizing adverse effects from market risks, including foreign exchange and credit risks[97] - The financial board is responsible for identifying and managing financial risks, ensuring adherence to approved policies[98] Taxation - The effective tax rate for the Group was 5.1% for the period ended March 31, 2023, up from 4.2% in the previous year[6]. - Unrecognized deferred tax assets related to net operating losses amounted to R$ 52,297 thousand as of March 31, 2023, compared to R$ 45,838 thousand as of March 31, 2022[43]. Other Financial Metrics - The Group's total expected credit loss increased to R$25,386 as of March 31, 2023, from R$24,365 as of December 31, 2022, representing an increase of approximately 4.2%[38] - The Group's trade and other payables decreased to R$91,391 as of March 31, 2023, from R$106,023 as of December 31, 2022, showing a reduction of approximately 13.8%[39] - The Group's contract assets decreased to R$86,751 as of March 31, 2023, from R$95,871 as of December 31, 2022, indicating a decline of approximately 9.5%[37] - The balance of derivative warrant liabilities increased to R$ 11,287 thousand as of March 31, 2023, from R$ 2,886 thousand at December 31, 2022[62]. - The Group recognized a loss on derivative financial instruments of R$ 8,738 thousand for the period ended March 31, 2023[57]. - The Group's financial covenants amount to R$33,562,000 as of March 31, 2023, down from R$37,494,000 as of December 31, 2022, with compliance confirmed for both periods[102] - There were no transfers between Level 1 and Level 2 for recurring fair value measurements during the periods presented[96]

Business Combination and Financial Overview - The Registrant completed the Business Combination on August 3, 2022, becoming the holding entity of Semantix[60]. - The financial statements reflect the historical operating results of Semantix prior to the Closing and the consolidated results as of December 31, 2022[61]. - The Registrant's financial statements are prepared in accordance with IFRS, with certain amounts and percentages rounded for presentation[62]. - The annual report includes non-GAAP financial measures such as EBITDA, Adjusted EBITDA, and Adjusted EBITDA Margin, which are used for decision-making and performance assessment[63]. - The aggregate gross proceeds from PIPE Financing amounted to $93,645,000, with 9,364,500 shares sold at $10.00 per share[44]. - The Company has a total of 18,499,984 warrants outstanding, consisting of 11,499,984 Public Warrants and 7,000,000 Private Warrants, each exercisable for one Ordinary Share at an exercise price of $11.50[58]. - The Company acquired Zetta Health Analytics S.A. in August 2022, focusing on SaaS data solutions in the healthcare sector[59]. Customer Concentration and Revenue Sources - The largest customer accounted for 18.1% of revenues in 2022, while the top ten customers together represented 50.2% of total revenues[78]. - Revenue from the proprietary SaaS business represented 21.0% of total revenues for the year ended December 31, 2022, up from 18.8% in 2021 and 4.7% in 2020[107]. - 26.7% of gross revenues for 2022 were attributable to the resale of software licenses from Cloudera, while 19.4% were from Elastic[97]. - Revenues from operations outside Brazil represented 9.6%, 12.0%, and 21.5% of total revenues for the years ended December 31, 2022, 2021, and 2020, respectively[164]. Financial Performance and Risks - The company incurred net losses of R$ 329.8 million, R$ 68.2 million, and R$ 19.4 million for the years ended December 31, 2022, 2021, and 2020, respectively, resulting in an accumulated deficit of R$ 468.9 million as of December 31, 2022[99]. - The company relies on a small number of customers for a significant portion of its revenues, which poses a risk if any major customer reduces or terminates their engagement[79]. - The contracts with customers typically have a term of one to three years but can be terminated at will with 30 to 90 days' notice[80]. - The ongoing economic uncertainty in Brazil may adversely affect the company's operations and share price[78]. - The company expects elevated costs and expenses due to its status as a public company and ongoing development of proprietary SaaS solutions, which may hinder future profitability[100]. Competition and Market Challenges - The company faces intense competition in the data cloud, big data, analytics, and artificial intelligence markets, which are characterized by rapid technological changes[86]. - The company faces competition from major public cloud providers like AWS, Azure, and GCP, which could impact its ability to provide competitive solutions[88]. - The company may not be able to renew or maintain reselling agreements with suppliers, which could adversely affect its cash position and revenue[98]. - The company may face challenges in maintaining or growing brand recognition, which is crucial for attracting and retaining customers[168]. Cybersecurity and Data Protection - The company is heavily dependent on information technology systems and any security breach could result in significant liabilities and reputational harm[188]. - The company faces increasing risks from cyber-attacks, including denial-of-service and ransomware attacks, which have escalated in number and sophistication[189]. - Security breaches may lead to significant legal liabilities, including potential claims from customers and stakeholders, which could adversely affect the company's reputation and financial condition[191]. - The company’s cybersecurity insurance coverage may be insufficient to cover large claims, potentially impacting its financial stability[193]. Regulatory Compliance and Legal Risks - The Brazilian Civil Rights Framework for the Internet imposes fines of up to 10% of the revenues of the relevant entity's economic group in Brazil for violations[208]. - The penalties for violations of the LGPD include fines of up to 2% of the company's or group's revenue, subject to a maximum of R$ 50 million per violation[213]. - The GDPR can result in administrative fines of up to €20 million or 4.0% of total worldwide annual revenue, whichever is higher[217]. - The company may face significant expenses and reputational harm due to potential litigation related to intellectual property claims[204]. - The company has implemented changes to comply with the LGPD, but ongoing compliance may require further action due to evolving regulations[212]. Growth Strategy and Future Outlook - The company plans to invest substantial time and resources to further expand its international operations, which may involve various operational challenges[167]. - The company expects fluctuations in its results of operations, making it difficult to plan and potentially leading to a decline in share price if expectations are not met[114]. - The company does not expect to reach its targets for proprietary SaaS revenues in 2023, citing unanticipated macroeconomic challenges and the need to adjust its proprietary SaaS portfolio[185]. - The company may seek acquisitions or strategic investments to enhance its data solutions and services, which could pose integration challenges and divert management attention[171].