Shuttle Pharmaceuticals (SHPH) - Prospectus(update)

As filed with the Securities and Exchange Commission on February 11, 2026 Registration No. 333-293363 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Amendment No. 1 To FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SHUTTLE PHARMACEUTICALS HOLDINGS, INC. (Exact name of registrant as specified in its charter) (State or other jurisdiction of incorporation or organization) (Primary Standard Industrial Delaware 2834 82-5089826 (I.R.S. Employer Identification No.) 401 Pr ...