Financial Performance - The company's operating revenue for 2021 was approximately ¥1.17 billion, representing a 75.28% increase compared to ¥665.96 million in 2020[30]. - The net profit attributable to shareholders for 2021 was approximately ¥282.22 million, an increase of 118.12% from ¥129.39 million in 2020[30]. - The net cash flow from operating activities for 2021 was approximately ¥452.94 million, reflecting a growth of 118.00% compared to ¥207.77 million in 2020[30]. - The total assets at the end of 2021 were approximately ¥1.79 billion, a 31.46% increase from ¥1.36 billion at the end of 2020[30]. - The net assets attributable to shareholders at the end of 2021 were approximately ¥1.33 billion, an 18.18% increase from ¥1.12 billion at the end of 2020[30]. - The basic earnings per share for 2021 were ¥4.55, a 117.70% increase compared to ¥2.09 in 2020[30]. - The diluted earnings per share for 2021 were also ¥4.55, reflecting the same growth rate of 117.70% from 2020[30]. - The weighted average return on equity for 2021 was 22.66%, an increase of 10.43 percentage points from 12.23% in 2020[30]. - The company achieved operating revenue of CNY 1,167.26 million, a year-on-year increase of 75.28%[173]. - The net profit attributable to shareholders reached CNY 282.22 million, up 118.12% year-on-year[173]. - The net profit after deducting non-recurring gains and losses was CNY 271.07 million, reflecting a growth of 119.53%[173]. - The net cash flow from operating activities was CNY 452.94 million, an increase of 118.00% compared to the previous year[173]. Dividend Distribution - The company plans to distribute a cash dividend of 13.70 RMB per 10 shares, totaling approximately 85,048,980.76 RMB, which represents 30.14% of the net profit attributable to shareholders[8]. - The company has not proposed any stock dividends or capital reserve transfers for the year 2021[8]. Research and Development - Research and development expenses accounted for 6.66% of operating revenue, a decrease of 0.39 percentage points compared to the previous year[32]. - The company is focusing on enhancing its R&D capabilities by investing in key technology platforms, including AI-based drug development and advanced formulation research[81]. - R&D expenses for the current year amounted to ¥77,758,296.33, representing an increase of ¥30,793,800.00 or 65.57% compared to the previous year[81]. - The company has developed a comprehensive preclinical drug R&D capability, providing one-stop services from lead compound screening to new drug clinical application submissions[68]. - The company has established a comprehensive service technology platform that meets international standards, integrating various research services including compound synthesis and toxicology safety evaluation[60]. - The company has established a high-activity laboratory and developed coupling methods for antibodies and linker-payloads in ADC drug research[42]. - The company has developed multiple raw material drug research platforms, including green chemistry and quality research platforms, to enhance drug development efficiency[72]. - The company has established a GMP-compliant oral solid preparation workshop to meet the production needs for clinical trials[72]. Market Position and Growth - The company is focused on expanding its market presence and enhancing its research capabilities in drug metabolism and pharmacokinetics[21]. - The CRO industry is projected to grow from approximately $68 billion in 2019 to $222 billion by 2024 in China, with a compound annual growth rate (CAGR) of about 26.5%[59]. - The company has established strong customer loyalty, leading to repeat collaborations with clients for new research needs[55]. - The company has built a robust marketing strategy, leveraging industry events and e-commerce platforms to expand its client base and influence[55]. - The company has established a strong international client base, including major pharmaceutical firms such as Takeda, Johnson & Johnson, and Roche, enhancing its reputation in the industry[161]. Operational Efficiency - The company has not yet achieved profitability since its listing[5]. - The company has detailed potential risks in its operations, which can be found in the "Risk Factors" section of the report[5]. - The company has received a standard unqualified audit report from its accounting firm[7]. - There are no non-operating fund occupations by controlling shareholders or related parties[10]. - The company does not have any special arrangements for corporate governance[12]. - The company has not violated decision-making procedures for providing guarantees[12]. - The company has received AAALAC certification and GLP certification from the National Medical Products Administration, highlighting its rare dual GLP qualification in the industry[60]. Client and Supplier Relations - The company has added 362 new clients during the reporting period, bringing the total number of clients to over 1,460[46]. - The top five suppliers accounted for a total procurement amount of 142.27 million RMB, representing 46.88% of the annual total procurement[194]. - The company did not rely on any single supplier for more than 50% of its total procurement, indicating a diversified supplier base[198]. Risks and Challenges - The report includes forward-looking statements that are subject to uncertainties and do not constitute substantive commitments to investors[9]. - The company faces risks related to potential loss of certifications, such as GLP and AAALAC, which could adversely affect its operations if not maintained[164]. - The company faced risks related to potential changes in tax incentives and government subsidies, which could impact profitability[173]. - The domestic CRO market is rapidly growing, with increasing competition from both international and domestic firms, necessitating continuous improvement in service capabilities[164].
美迪西(688202) - 2021 Q4 - 年度财报