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苑东生物(688513) - 2020 Q4 - 年度财报

Financial Performance - The company's operating revenue for 2020 was RMB 921,918,474.02, a decrease of 2.67% compared to 2019[28]. - The net profit attributable to shareholders for 2020 was RMB 178,161,834.51, an increase of 64.04% year-on-year[33]. - The net cash flow from operating activities for 2020 was RMB 156,524,544.27, representing a 10.36% increase from the previous year[28]. - The total assets at the end of 2020 were RMB 2,530,857,158.85, a 156.40% increase compared to the end of 2019[31]. - The basic earnings per share for 2020 was RMB 1.78, up 47.11% from RMB 1.21 in 2019[32]. - The company's net assets attributable to shareholders increased by 200.42% to RMB 2,095,247,258.95 at the end of 2020[31]. - The company's main business revenue decreased by 2.72% to 921.48 million yuan, primarily due to significant price reductions in certain drugs[144]. - The net profit attributable to the parent company was 178.16 million yuan, a year-on-year increase of 64.04%[136]. - Government subsidies accounted for 33.98% of the total profit, amounting to 67.64 million yuan during the reporting period[135]. Dividend and Share Capital - The company plans to distribute a cash dividend of RMB 3.00 per 10 shares, totaling approximately RMB 36,027,000, which represents 20.22% of the net profit attributable to shareholders for 2020[6]. - As of December 31, 2020, the total share capital of the company was 120,090,000 shares[6]. - The company does not plan to issue bonus shares or convert capital reserves into share capital[6]. - The company issued 30,090,000 shares in 2020, raising a total of RMB 1,334,792,400.00[33]. Research and Development - Research and development expenses accounted for 16.69% of operating revenue in 2020, slightly up from 16.53% in 2019[32]. - The total R&D investment for the year was approximately ¥153.91 million, a decrease of 1.70% compared to the previous year[71]. - R&D investment accounted for 16.69% of total operating revenue, an increase of 0.16 percentage points from the previous year[71]. - The company has independently undertaken four major new drug creation projects and holds 78 authorized patents, including 14 international patents, showcasing its robust R&D capabilities[59]. - The company has a strong pipeline of innovative drugs, including the EP-0061I + EP-0061A project, which is a controlled substance with high development difficulty[82]. - The company is committed to innovation-driven development as a core strategy since its establishment[196]. - The company has established a comprehensive R&D model, focusing on clinical needs and leveraging international cooperation for innovative drug development[49]. Market Position and Strategy - The company aims to become a global leader in specialty patented prescription drugs, targeting unmet clinical needs in key therapeutic areas[44]. - The company is positioned to capitalize on the shift towards innovative drug development, particularly in addressing major diseases and rare conditions[63]. - The company has established a comprehensive quality management system, becoming the first in Southwest China to pass the new GMP certification for sterile preparations[103]. - The company is enhancing its distribution network to cover secondary and tertiary markets, leveraging opportunities from national drug procurement policies[53]. - The company is focusing on innovation and transformation in response to competitive pressures from national procurement and the COVID-19 pandemic, aiming to establish a differentiated advantage in the market[63]. Risks and Compliance - The company has detailed various risks and countermeasures in its annual report, emphasizing the importance of investor awareness regarding investment risks[4]. - The company is facing risks related to core technology not forming products or not meeting expectations, which could impact its competitive edge[121]. - The company is exposed to risks from government-led centralized procurement, which could lead to significant price reductions for its products[125]. - There are no violations of decision-making procedures regarding external guarantees[11]. Production and Sales - The production volume of Fumaric Acid Bisoprolol Tablets reached 2,496.26 million boxes, an increase of 115.32% year-on-year, while sales volume was 2,005.76 million boxes, up 62.38% year-on-year[148]. - The sales volume of Ibuprofen Injection increased significantly by 314.68% year-on-year, with production volume at 267.84 million units[148]. - The total sales revenue from the top five customers amounted to 48,069.06 million yuan, accounting for 52.14% of the annual total sales[156]. - The company achieved total operating revenue of 921.92 million yuan, a year-on-year decrease of 2.67%[136]. Financial Health - Cash and cash equivalents at the end of the period amounted to ¥1,055,289,158.05, representing 41.70% of total assets, an increase of 161.17% compared to the previous period[168]. - The company's short-term borrowings increased by 752.62% to ¥40,028,171.23, reflecting an increase in bank loans during the year[171]. - The company's accounts payable rose by 139.83% to ¥122,731,998.27, primarily due to an increase in payable engineering costs during the reporting period[171]. - Deferred income increased by 302.00% to ¥50,334,863.16, attributed to an increase in government subsidies related to assets received during the period[171]. Government Policies and Industry Trends - The pharmaceutical industry in China is expected to maintain stable growth due to increasing demand driven by economic development and an aging population[54]. - The National Medical Insurance Bureau adjusted the drug list, adding 119 new drugs and removing 29, resulting in a total of 2800 drugs in the directory[183]. - The adjustment is expected to reduce patient burdens by approximately 28 billion yuan in 2021 through negotiated price reductions and insurance reimbursements[183]. - The new drug list includes 96 exclusive drugs, most of which were negotiated for price reductions, promoting innovation in the pharmaceutical industry[183].