
Core Viewpoint - AnaptysBio, Inc. shares experienced a significant rally of 30.5% following positive results from a mid-stage study of its investigational candidate, rosnilimab, for moderate-to-severe rheumatoid arthritis, despite a prior 17% loss over the past four weeks [1][2]. Company Performance - AnaptysBio's stock closed at $16.15 after notable trading volume [1]. - The company is expected to report a quarterly loss of $1.61 per share, reflecting a year-over-year change of -1.3%, with anticipated revenues of $10.17 million, representing a 12.8% increase from the previous year [3]. Study Results - Rosnilimab met its primary endpoint in the phase IIb RENOIR study for rheumatoid arthritis, achieving statistical significance at one dose and numerical superiority across all doses at week 12 [2]. - The study also achieved key secondary endpoints, with the highest responses recorded at week 14, despite elevated placebo rates [2]. - Full 28-week data from the RA study is expected to be shared in Q2 2025, and top-line data for ulcerative colitis is anticipated in Q4 2025 [2]. Earnings Estimates - The consensus EPS estimate for AnaptysBio has been revised 5.4% higher over the last 30 days, indicating a positive trend that may lead to price appreciation [4]. - The stock currently holds a Zacks Rank of 2 (Buy), suggesting potential for further strength [4]. Industry Context - AnaptysBio operates within the Zacks Medical - Biomedical and Genetics industry, where another company, Pacira, has also shown strong performance with a 32.6% return over the past month [4]. - Pacira's consensus EPS estimate has increased by 4.1% to $0.85, although this reflects a year-over-year change of -4.5% [5].