Core Viewpoint - CICC maintains its earnings forecast for Zai Ding Pharmaceutical (09688) for 2025 and 2026, with a target price of HKD 34.41/USD 44.24 based on DCF model, and continues to rate it as outperforming the industry [1] Group 1: Product Approval and Administration - The FDA has approved the subcutaneous pre-filled injection of Efgartigimod, which can be administered by patients, caregivers, or healthcare professionals, taking 20-30 seconds per injection [2] - Efgartigimod's approval is based on its bioequivalence to the vial formulation, and the company plans to submit a domestic application for the pre-filled injection by 2025 [2] Group 2: Efgartigimod's Efficacy - Efgartigimod is considered the best therapy for gMG, with a cumulative achievement rate of 40%-73% for minimal symptom expression (MG-ADL ≤ 1), significantly outperforming competitors [3] - The drug shows rapid onset of action, with significant improvement in ADL within the first week and a 73.0% improvement by week four [3] - Long-term efficacy is supported by a three-year follow-up study (ADAPT+), demonstrating sustained effectiveness with a controlled infection risk and a serious adverse event rate of 4.8% [3] Group 3: Upcoming Catalysts and Product Developments - The company has a rich pipeline with several key products expected to report critical data, including ZL-1310 (DLL3 ADC) with positive ORR data expected in 1H25 [4] - Bemarituzumab (FGFR2b) is anticipated to report clinical data from the global Phase III FORTITUDE-101 study in 1H25, followed by a domestic NDA submission [4] - KarXT has received FDA approval, with its domestic application accepted in January 2025, and results for the global Phase III data for ADP are expected in 2H25 [4] - The company plans to submit domestic applications for tumor electric field therapy for pancreatic cancer and non-small cell lung cancer by 2025 [4]
中金：维持再鼎医药(09688)跑赢行业评级 目标价34.41港元