Bloomage Biotech(SH:688363) Zhong Guo Jing Ji Wang·2025-04-27 05:51Group 1: Aging Research and ECM - The 13th aging biomarker, "changes in the extracellular matrix (ECM)," has been added to the influential aging classification standards, highlighting its core role in human aging [1] - The decline in ECM viscoelasticity during aging is linked to various health improvements, including reduced cancer incidence and improved muscle function when high molecular weight hyaluronic acid (HA) is introduced [1] - ECM is a dynamic network that includes HA, collagen, and elastin, and its degradation accelerates systemic aging by affecting mitochondrial homeostasis and inflammation [1] Group 2: Role of Hyaluronic Acid - Hyaluronic acid (HA) plays a crucial role in ECM aging, providing structural support for collagen and activating fibroblasts through signaling pathways [2] - The interaction between HA and collagen is essential for ECM function, and a decline in HA leads to impaired collagen synthesis and overall aging [2] - Traditional anti-aging strategies often focus on single components, but a systemic approach that includes high molecular weight HA can restore ECM balance and promote long-term repair [2] Group 3: Company Insights - Huaxi Biological, a leader in the hyaluronic acid sector, has developed a unique polysaccharide research and development platform and holds a significant position in the global sugar biology industry [3] - The company’s product "Runbaiyan.BoBo," a hyaluronic acid sodium solution with lidocaine, has received approval as a Class III medical device, marking a significant advancement in ECM aging intervention research [3] - The approval of this product indicates stricter regulations in the market, raising entry barriers and promoting industry standardization [3]