长春高新:创新布局妇儿健康等领域,多条研发管线进展显著

Core Viewpoint - Changchun High-tech (000661) held an investor conference after releasing its 2024 annual report, highlighting its focus on R&D innovation and the progress of multiple drug pipelines, particularly in the fields of women's and children's health [1][2]. Financial Performance - The company invested nearly 2.7 billion yuan in R&D in 2024, sacrificing short-term performance for long-term growth [1]. - The 2024 annual report indicated that the company's performance was not outstanding, but the results of increased R&D investment in recent years are noteworthy [1]. Product Pipeline - Five major products from the core subsidiary, Jinsai Pharmaceutical, were approved for market launch in early 2024, including: - Recombinant human follicle-stimulating hormone injection (Jinsai Heng) - Acetate medroxyprogesterone oral suspension (Meishiya) - Progesterone injection (II) (Jinsai Xin) - Oral gel (Yipushu) - Innovative traditional Chinese medicine pediatric cough granules (Jinsai Ke) [1]. Clinical Trials and Innovations - The company showcased several promising drug candidates during the investor call, including: - Vuxin Qibai monoclonal antibody, which is expected to be the first IL-1β monoclonal antibody approved in China for adult gouty arthritis, showing significant efficacy and safety in clinical trials [2]. - GS1-144 tablets, a novel NK3R small molecule antagonist for menopausal vasomotor symptoms, currently in phase II clinical trials domestically and phase I in Australia [2]. - GenSci120 injection, a humanized anti-PD-1 monoclonal antibody for systemic lupus erythematosus and other autoimmune diseases, with IND approvals expected in early 2025 [3]. Strategic Focus - The company is actively advancing its R&D efforts across various therapeutic areas, including women's and children's health, metabolism, autoimmune diseases, oncology, vaccines, and traditional Chinese medicine, aiming to reduce reliance on single products [4].