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Immuneering Reports First Quarter 2025 Financial Results and Provides Business Updates

Core Insights - Immuneering Corporation reported positive data from its ongoing Phase 2a trial of IMM-1-104, showing encouraging responses in pancreatic cancer treatment [1][3] - The company has extended its cash runway into 2026, ensuring sufficient funding for ongoing operations [1][8] - Dr. Igor Matushansky has been appointed as Chief Medical Officer to lead clinical efforts, particularly for the upcoming Phase 3 trial in first-line pancreatic cancer [1][5] Clinical Developments - The Phase 2a trial of IMM-1-104 has shown exceptional efficacy, with a third-line monotherapy patient achieving over 13 months of progression-free survival and a first-line combination therapy patient achieving a complete response [3][5] - A clinical trial supply agreement has been established with Regeneron Pharmaceuticals to evaluate IMM-1-104 in combination with Libtayo® for non-small cell lung cancer [1][4] Financial Performance - As of March 31, 2025, the company reported cash and cash equivalents of $35.9 million, a slight decrease from $36.1 million at the end of 2024 [11] - Research and Development (R&D) expenses for Q1 2025 were $11.5 million, up from $11.2 million in Q1 2024, primarily due to increased clinical costs [11] - The net loss for Q1 2025 was $15.0 million, or $0.42 per share, compared to a net loss of $14.3 million, or $0.49 per share, in Q1 2024 [11][16]