规范诊疗之下,红斑狼疮病情可控(服务窗)
Ren Min Ri Bao·2025-05-08 22:10

Core Viewpoint - Systemic lupus erythematosus (SLE), commonly known as lupus, is a chronic autoimmune disease affecting multiple systems and organs, primarily seen in young women of childbearing age. Although there is currently no cure, advancements in medical treatments, particularly in biological agents, have significantly improved patient survival rates, with a 5-year survival rate exceeding 90% and a nearly 90% 10-year survival rate [1][2]. Group 1: Disease Understanding - Lupus is characterized by an immune system that mistakenly attacks healthy tissues and organs, leading to various symptoms [1]. - Common symptoms include a butterfly-shaped rash on the face, hair loss, oral ulcers, joint stiffness, muscle weakness, and kidney issues such as blood in urine [2]. - The clinical manifestations of lupus can vary widely among patients, necessitating a tailored treatment approach based on individual symptoms and organ involvement [2]. Group 2: Diagnosis and Treatment - Routine health check-ups may not detect lupus directly, but they can reveal abnormalities such as anemia and low white blood cell counts, which are associated with the disease [1]. - Certain tests, including screenings for antinuclear antibodies and anti-double-stranded DNA antibodies, can aid in early detection of lupus [1]. - Current treatment primarily involves corticosteroids and traditional immunosuppressants, with biological agents gaining prominence for their ability to reduce side effects and improve overall disease prognosis [2]. Group 3: Patient Management - Patients are advised to avoid factors that may exacerbate their condition, such as sun exposure, fatigue, and infections [2]. - A positive mindset and a healthy lifestyle are emphasized as crucial for managing lupus effectively and improving quality of life [2].