Nature：炎症是衰老之源

Group 1 - Chronic inflammation is identified as a significant factor accelerating aging, linked to the dysfunction of calcium signaling in macrophage mitochondria [1][2][4] - The process is described as "mitochondrial calcium signaling dysfunction → chronic immune activation → inflammatory aging" [3] - Chronic inflammation negatively impacts various body systems, including the brain, muscles, and metabolic health, increasing risks for diseases like Alzheimer's and type 2 diabetes [5][6] Group 2 - Lifestyle adjustments can effectively regulate inflammation levels and promote healthier aging [6] - A multi-dimensional strategy is recommended, including dietary changes, regular exercise, adequate sleep, stress management, and maintaining a healthy weight [7][32] Group 3 - Anti-inflammatory foods include colorful fruits and vegetables, omega-3 fatty acids, whole grains, and spices like turmeric [9][10][11][12] - It is advised to avoid pro-inflammatory foods such as sugar, unhealthy fats, and processed meats [14][15][16] Group 4 - Regular exercise is emphasized as a powerful tool against inflammation, with both aerobic and strength training recommended [20][23] - Sleep quality is crucial, with a target of 7-9 hours per night to reduce inflammation markers [27][28] Group 5 - Chronic psychological stress is linked to increased inflammation, and stress management techniques like mindfulness and yoga are suggested [29][31] - Environmental factors, such as pollution and chemical exposure, should be minimized to reduce inflammation [34]