港股石药集团跌超5%，创三周最大下跌。此前Jefferies下调股票评级至落后大盘，并称公司所有利好均已反映在股价中，且关键产品销售持续面临阻力。

Group 1 - The stock of the company, CSPC Pharmaceutical Group, fell over 5%, marking the largest decline in three weeks [1] - Jefferies downgraded the stock rating to "underperform," indicating that all positive factors have already been reflected in the stock price [1] - The company continues to face sales challenges for key products [1]