爸妈的基因谁对你影响更大？

Group 1 - The core concept of epigenetics is introduced, highlighting that even with the same genetic makeup, the effects can differ due to epigenetic factors [3][11] - The discussion includes the importance of both maternal and paternal contributions to genetic expression, emphasizing that both are necessary for normal development [10][31] - The phenomenon of genomic imprinting is explained, where certain genes are expressed based on their parental origin, leading to different outcomes despite identical genetic sequences [11][27] Group 2 - The presentation discusses specific genetic disorders, such as Prader-Willi syndrome and Angelman syndrome, which arise from the same genetic defect but result in different diseases due to the parent-of-origin effects of imprinted genes [23][28] - The role of DNA methylation as a key epigenetic modification is highlighted, explaining how it influences gene expression and the identification of parental origin [34][37] - The concept of a "methylation clock" is introduced, indicating that DNA methylation patterns can serve as biomarkers for aging and may change over time, potentially leading to age-related diseases [45][50]