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Castle Biosciences Enters Collaboration and License Agreement with SciBase to Develop Diagnostic Tests for Dermatologic Diseases

Core Insights - Castle Biosciences has entered a collaboration and license agreement with SciBase to develop a diagnostic test aimed at predicting flares in patients with atopic dermatitis [1][2][3] - The collaboration targets a potential market of up to 24 million patients in the United States suffering from atopic dermatitis, many of whom experience flares while on maintenance treatment [2][3] - SciBase's technology will be utilized to enhance patient care in dermatology, complementing Castle's existing portfolio of tests for skin cancers and other dermatological conditions [3][5] Company Overview - Castle Biosciences is a diagnostics company focused on innovative tests that guide patient care, with a mission to transform disease management [4] - The company's current portfolio includes tests for skin cancers, Barrett's esophagus, and uveal melanoma, along with ongoing research for additional tests in high clinical need areas [5] Collaboration Details - Under the agreement, both companies will explore various clinical indications related to dermatologic diseases, with SciBase focusing on the EU, Switzerland, UAE, Japan, and South Korea, while Castle will target North America [3] - SciBase will receive a single-digit royalty on Castle's gross margin and a low double-digit percentage markup on product sales, along with a milestone payment of 5 million USD when Castle's sales reach 50 million USD annually [3]