世卫组织警告基孔肯雅热或流行：病毒有何特性？如何检测

Core Insights - Chikungunya virus has become a significant concern, with 119 countries and regions reporting its spread, affecting approximately 5.5 million people at risk of infection, potentially leading to widespread outbreaks and pressure on healthcare systems [1] - In 2023, an estimated one-third of the population in Réunion Island, a French territory in the Indian Ocean, has been infected, with cases also reported in India, Bangladesh, and several European countries [1] - As of July 21, 2025, Foshan has reported a total of 2,659 confirmed cases of Chikungunya fever, all mild, with no severe cases or deaths reported [1] Disease Characteristics - Chikungunya virus belongs to the family of flaviviruses and is a single-stranded positive-sense RNA virus, with a spherical shape and a diameter of approximately 50 nanometers [3] - The virus can be classified into multiple genotypes, which differ in pathogenicity and transmission capabilities, affecting the severity of outbreaks [3] - There is currently no vaccine or specific treatment for Chikungunya; symptomatic treatment is provided, primarily for fever and pain relief [3] Prevention and Control Measures - Key aspects of infectious disease control include early detection, diagnosis, and treatment of cases, with Foshan's medical institutions reporting positive cases on the same day to the national disease control network [4] - During the rainy season, controlling mosquito populations is crucial, as Aedes mosquitoes breed in small water containers; community mobilization for environmental cleanup is recommended [4] - Preventive measures include regular cleaning of potential mosquito breeding sites and personal protective actions such as wearing long sleeves and using mosquito repellent [9] Diagnostic Methods - Various diagnostic methods are employed for Chikungunya, including RT-PCR for detecting viral RNA within the first week of illness, which is considered the gold standard for early diagnosis [6][8] - Serological tests for IgM and IgG antibodies are also used, with IgM indicating recent infection and IgG suggesting past infection [6][8] - Laboratory testing is essential for confirming Chikungunya fever, with RT-PCR showing high sensitivity during the acute phase [7][8]