BioCryst Announces Charlie Gayer to Succeed Jon Stonehouse as Chief Executive Officer Upon his Retirement in December

Core Viewpoint - BioCryst Pharmaceuticals announces the retirement of CEO Jon Stonehouse, effective December 31, 2025, with Charlie Gayer appointed as the new CEO starting January 1, 2026, following his role as Chief Commercial Officer [1][2][4] Company Leadership Transition - Jon Stonehouse will remain on the board of directors after his retirement [2] - Charlie Gayer has been instrumental in the successful launch of ORLADEYO (berotralstat), which is projected to achieve peak sales of $1 billion [3][4] Strategic Direction and Achievements - Under Stonehouse's leadership, BioCryst has become a profitable company with a strong future, focusing on delivering life-changing therapies [4] - Gayer's promotion reflects the company's succession planning, emphasizing his proven track record and ability to enhance the company's mission [4] Background of New CEO - Charlie Gayer joined BioCryst in 2015 and became CCO in January 2020, previously holding leadership roles in rare disease categories at Talecris Biotherapeutics and Grifols [5] - Gayer has a strong educational background with a B.A. from Princeton University and an M.B.A. from Duke University [5] Company Overview - BioCryst Pharmaceuticals is dedicated to improving the lives of patients with hereditary angioedema and other rare diseases, focusing on developing innovative oral small-molecule and protein therapeutics [6]