RESEARCH TRIANGLE PARK, N.C., Oct. 20, 2025 (GLOBE NEWSWIRE) -- BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX) today announced that the company will report its third quarter 2025 financial results on Monday, November 3, 2025. BioCryst management will host a conference call and webcast at 8:30 a.m. ET that day to discuss the financial results and provide a corporate update. The live call may be accessed by dialing 1-844-481-2942 for domestic callers and 1-412-317-1866 for international callers. A live webcast ...

Core Insights - BioCryst Pharmaceuticals (BCRX) shares increased by 6.1% to $6.81, following a significant trading volume, contrasting with a 17.2% decline over the past month [1][2] Company Developments - The stock surge is attributed to a $700 million acquisition agreement for Astria Therapeutics, which will enhance BCRX's pipeline with navenibart, a long-acting injectable therapy for hereditary angioedema (HAE) [2] - The acquisition is expected to drive double-digit revenue growth, profit accretion, and rapid market adoption, indicating a strategic fit with BCRX's existing commercialization platform [2] Financial Performance Expectations - BioCryst is projected to report quarterly earnings of $0.06 per share, reflecting a year-over-year increase of 185.7%, with revenues anticipated at $161.15 million, a 37.6% rise from the previous year [3] - However, the consensus EPS estimate has been revised down by 4.8% over the last month, which may impact future stock price movements [4] Industry Context - BioCryst is categorized under the Zacks Medical - Drugs industry, where Ironwood Pharmaceuticals (IRWD) also operates, having seen an 8.8% increase in its stock price recently [4] - Ironwood's EPS estimate remains unchanged at $0.09, indicating a significant year-over-year change of 350% [5]

BioCryst Pharmaceuticals has signed a definitive agreement to buy Astria Therapeutics with a mix of cash and stock transactions. The deal values Astria at an implied $13 per share, culminating in an enterprise value of around $700m. The companies’ boards of directors have unanimously approved the acquisition and the transaction will be finalised in the first quarter of 2026. Upon completion, Astria CEO Jill Milne will join the BioCryst board of directors. The acquisition is expected to provide strategic ...

PresentationI would now like to turn the conference over to Nick Wilder with BioCryst. Please go ahead.Good day, and welcome to the BioCryst Pharmaceuticals Conference Call. [Operator Instructions] Please note this event is being recorded.Nick Wilder Good morning, and welcome to BioCryst's conference call to discuss its proposed acquisition of Astria Therapeutics. Participating with me today are CEO, Jon Stonehouse; President and Chief Commercial Officer, Charlie Gayer; and Chief Financial Officer, Babar Gh ...

Core Viewpoint - BioCryst Pharmaceuticals has agreed to acquire Astria Therapeutics for an implied value of $13 per share, totaling approximately $700 million in enterprise value, with the transaction expected to close in the first quarter of 2026 [1][2]. Acquisition Details - The acquisition will consist of $8.55 in cash and 0.59 shares of BioCryst stock for each share of Astria [1]. - Astria focuses on therapies for allergic and immunologic diseases, with its lead product candidate being Navenibart, an injectable monoclonal antibody for hereditary angioedema (HAE) prophylaxis [3][4]. Strategic Importance - Navenibart's clinical profile and administration schedule could significantly improve treatment options compared to existing therapies [3]. - BioCryst's established infrastructure in HAE is expected to enhance the market reach of Navenibart, which will complement its existing portfolio of oral and potential injectable therapies for HAE [4][5]. Market Potential - The addressable market for Navenibart includes over 5,000 patients currently treated with injectable prophylaxis, potentially driving double-digit revenue growth for BioCryst over the next decade [6]. - The transaction is anticipated to be accretive to adjusted operating profit in the first full year following Navenibart's expected launch [6]. Funding Mechanism - BioCryst has secured a debt commitment letter for a strategic financing facility with Blackstone, with a total capacity of up to $550 million to fund the acquisition [7][8]. - The cash portion of the acquisition will be financed through existing cash and a portion of the Blackstone facility [8]. Shareholder Impact - Following the acquisition, Astria stockholders will own approximately 15% of the pro forma equity in the combined company [8].

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Core Insights - Investors in BioCryst Pharmaceuticals, Inc. (BCRX) should monitor the stock closely due to significant activity in the options market, particularly the Mar 20, 2026 $2.00 Call, which has shown high implied volatility [1] Company Overview - BioCryst Pharmaceuticals is currently rated as a Zacks Rank 1 (Strong Buy) in the Medical - Drugs industry, which is positioned in the top 28% of the Zacks Industry Rank [3] - Over the past 60 days, one analyst has raised the earnings estimates for the current quarter, resulting in an increase in the Zacks Consensus Estimate from earnings of 4 cents per share to 5 cents per share [3] Market Sentiment - The high implied volatility in options trading suggests that investors are anticipating a significant price movement for BioCryst Pharmaceuticals shares, potentially due to an upcoming event that could trigger a rally or sell-off [2][4] - Options traders often seek to capitalize on high implied volatility by selling premium, aiming for the underlying stock to not move as much as expected by expiration [4]

BioCryst Pharmaceuticals (NasdaqGS:BCRX) M&A Announcement October 14, 2025 08:00 AM ET Speaker1Good day and welcome to the BioCryst Pharmaceuticals conference call. All participants will be in a listen-only mode. Should you need assistance, please signal a conference specialist by pressing the star key followed by zero. After today's presentation, there will be an opportunity to ask questions. To ask a question, you may press star then one on a touchtone phone. To withdraw your questions, please press star ...

Acquisition Overview - BioCryst is set to acquire Astria for approximately $700 million in total enterprise value [14, 37] - Astria stockholders are expected to own 15% of the pro forma equity [37] - The transaction is expected to close in Q1 2026 [38] Strategic Rationale - The acquisition expands and strengthens BioCryst's presence in the HAE market [14] - It is expected to transform BioCryst's revenue profile through the next decade, with double-digit portfolio CAGR [14] - The acquisition reinforces operational and financial excellence with continued profitability (non-GAAP) and cash flow generation expected [39] Navenibart Potential - Navenibart, Astria's late-stage asset, has the potential to be a best-in-class injectable prophylactic therapy for HAE [14, 39] - Phase 1b/2 data indicates potential for best-in-class efficacy with a favorable safety profile, and infrequent 3-to-6-month dosing [14, 17] - Navenibart could address a market of 5,000+ patients in the US [22] Financial Impact - BioCryst expects to remain profitable (non-GAAP) and cash flow positive post-transaction [14, 37] - The transaction is expected to be significantly accretive to operating profit (non-GAAP) in the first full year of launch [37] - BioCryst anticipates a cash balance of over $1 billion by 2029 [14, 35]

BioCryst Pharmaceuticals said on Tuesday it would buy Astria Therapeutics in a cash-and-stock deal valued at about $700 million, as it looks to expand its portfolio of treatments for rare diseases. ...