RESEARCH TRIANGLE PARK, N.C., July 09, 2025 (GLOBE NEWSWIRE) -- BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX) today announced that the company will present new findings from patient-focused research highlighting the burden of current treatments for HAE on pediatric patients under the age of 12 and their caregivers and perspectives on the importance of HAE treatments. The findings will be presented in posters at the 2025 US HAEA National Summit in Baltimore, which is taking place July 10-13, 2025. “For more ...

For those looking to find strong Medical stocks, it is prudent to search for companies in the group that are outperforming their peers. Is BioCryst Pharmaceuticals (BCRX) one of those stocks right now? Let's take a closer look at the stock's year-to-date performance to find out.BioCryst Pharmaceuticals is a member of our Medical group, which includes 987 different companies and currently sits at #6 in the Zacks Sector Rank. The Zacks Sector Rank includes 16 different groups and is listed in order from best ...

Summary of BioCryst Pharmaceuticals (BCRX) Conference Call Company Overview - **Company**: BioCryst Pharmaceuticals (BCRX) - **Event**: Conference call regarding the sale of the European business - **Date**: June 27, 2025 Key Points Industry and Company Strategy - BioCryst Pharmaceuticals is focused on creating value through three main drivers: 1. Establishing ORLIDEAL as a global market leader with a target of $1 billion in peak revenue [5] 2. Launching new products from its pipeline to ensure sustainable growth [6] 3. Strengthening financial independence and profitability to facilitate business development opportunities [6] Sale of European Business - BioCryst announced the sale of its European business to NeoPharmad Gentile (NG) for $250 million, which includes the PEOPLE and Orlodayo products in Europe [5][6] - The deal is expected to provide up to $14 million in future milestones related to sales in Central and Eastern Europe [7] - The European business accounts for less than 10% of global sales and has lower margins compared to other regions [7] Financial Impact - The upfront cash from the sale will be used to pay off all remaining term debt, saving approximately $70 million in interest payments over the loan's remaining life [8] - By the end of 2027, BioCryst anticipates having nearly $700 million in cash with no term debt, an improvement of about $400 million in net cash from previous projections [8] - The transaction is expected to significantly enhance profitability by focusing on higher-margin business primarily in the U.S. [8] Royalty Structure - The agreement allows BioCryst to benefit from European revenue in global royalty calculations, with NG responsible for royalties from European sales [10] - This structure will help reduce future royalty payments significantly once certain thresholds are reached [10] Future Growth and Pipeline - BioCryst is excited about two main pipeline programs: 17,725 for Netherlands and oral staff for DME, and is in a stronger financial position to fund these programs [23] - The company does not plan to expand its sales force but aims to optimize performance with the existing team of 40 representatives [24] Business Development Strategy - BioCryst is looking to acquire additional products, particularly in the rare disease space, with a focus on later-stage programs [32] - The company aims to be a consolidator in the U.S. market, similar to NG's strategy in Europe [33] Regulatory Updates - The PDUFA date for the pediatric Orlodayo NDA has been extended to December 12 due to a major amendment, but the company remains confident about the product's potential [51] Cost Savings - The sale is expected to result in a minimum of $50 million in annual operating expense savings, effective after the transaction closes [61] Additional Insights - The transaction aligns with BioCryst's strategy to enhance financial strength and operational efficiency [13] - The company emphasizes the importance of cash flow and profitability, particularly from the U.S. market, which is seen as the most valuable contributor to the company's financial health [26] This summary encapsulates the key discussions and strategic insights from the BioCryst Pharmaceuticals conference call, highlighting the company's focus on financial strength, strategic sales, and future growth opportunities.

—Neopharmed Gentili will pay BioCryst $250 million upfront for the European assets and rights related to ORLADEYO, and up to $14 million in future milestones— —BioCryst plans to use proceeds to retire all remaining term debt, which will eliminate approximately $70 million of future interest payments over remaining life of the loan— —With this transaction, BioCryst expects to end 2027 with approximately $700 million in cash and no term debt (an increase of $400 million from prior 2027 net cash guidance)— RES ...

BioCryst Pharmaceuticals (BCRX) appears an attractive pick, as it has been recently upgraded to a Zacks Rank #1 (Strong Buy). An upward trend in earnings estimates -- one of the most powerful forces impacting stock prices -- has triggered this rating change.The sole determinant of the Zacks rating is a company's changing earnings picture. The Zacks Consensus Estimate -- the consensus of EPS estimates from the sell-side analysts covering the stock -- for the current and following years is tracked by the syst ...

Company Performance - Acurx Pharmaceuticals, Inc. (ACXP) has returned 0.8% year-to-date, outperforming the Medical sector, which has returned an average of -4.7% [4] - The Zacks Consensus Estimate for ACXP's full-year earnings has increased by 60.5% over the past quarter, indicating improved analyst sentiment and a stronger earnings outlook [4] Industry Ranking - Acurx Pharmaceuticals belongs to the Medical - Biomedical and Genetics industry, which has 502 stocks and is currently ranked 88 in the Zacks Industry Rank. This industry has lost an average of 4.8% year-to-date, showing that ACXP is performing better than its peers [6] - The Medical group, which includes Acurx Pharmaceuticals, is ranked 6 within the Zacks Sector Rank, indicating a relatively strong position among 16 sector groups [2] Comparison with Peers - BioCryst Pharmaceuticals (BCRX) has also outperformed the Medical sector with a year-to-date return of 32.6% and has a Zacks Rank of 2 (Buy) [5] - The consensus EPS estimate for BioCryst Pharmaceuticals has increased by 339.6% over the past three months, highlighting significant positive analyst sentiment [5]

RESEARCH TRIANGLE PARK, N.C., June 13, 2025 (GLOBE NEWSWIRE) -- BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX) today announced that the National Institute of Drug and Food Surveillance (INVIMA) in Colombia has granted approval for oral, once-daily ORLADEYO® (berotralstat) for the prophylaxis of hereditary angioedema (HAE) attacks in adults and pediatric patients 12 years of age or older. “Today’s announcement marks another important step toward bringing ORLADEYO to people living with HAE who are in need of n ...

ORLADEYO® (berotralstat) now reimbursed in the NetherlandsRESEARCH TRIANGLE PARK, N.C., June 06, 2025 (GLOBE NEWSWIRE) -- BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX) today announced that, following a positive recommendation from the Zorginstituut Nederland, ORLADEYO® (berotralstat) has been approved for the routine prevention of hereditary angioedema (HAE) attacks in patients aged 12 years and older. This reimbursement approval in the Netherlands marks national reimbursement for ORLADEYO across all major ...

Summary of BioCryst Pharmaceuticals (BCRX) Conference Call Company Overview - **Company**: BioCryst Pharmaceuticals (BCRX) - **Focus**: Rare diseases, specifically targeting hereditary angioedema (HAE) with its lead drug Orlodayo, which is in its fifth year of launch [4][6] Financial Performance - **Profitability**: Expected to be profitable in 2025, with a strong financial position and debt reduction already achieved this year [5][68] - **Revenue Guidance**: Increased revenue guidance for 2025 to $580 million - $600 million from a previous estimate of $535 million - $550 million, driven by strong demand and patient access to paid therapy [6][7] Product Pipeline Orlodayo - **Market Performance**: Strong demand from both patients and physicians, particularly in the Medicare and commercial populations [7] - **Pediatric Opportunity**: FDA accepted the supplemental NDA for pediatric use with a PDUFA date set for September 12, 2025 [8][9] Netherton Syndrome (Drug: 17725) - **Mechanism of Action**: KLK5 inhibitor targeting a genetic disorder with a clear mechanism involving faulty gene function leading to uncontrolled KLK5 activity [12][13] - **Clinical Trials**: Initial evaluations in healthy volunteers have been positive, allowing progression to patient trials [20][21] - **Study Design**: Phase one study designed to assess drug penetration and skin healing, with a focus on skin outcomes and patient-reported outcomes [31][36] - **Market Opportunity**: Estimated 1,600 Netherton patients in the U.S., with potential growth as targeted therapy becomes available [49][50] Diabetic Macular Edema (DME) - **Drug: Vorlestat**: Lower solubility drug being developed for a suprachoroidal delivery approach, aiming for sustained exposure at the retina [58][60] - **Preclinical Data**: Positive results in animal models showing significant reduction in retinal vascular leakage, supporting the mechanism for DME treatment [63][64] - **Phase One Study**: Small study focusing on safety and retinal thickness changes over time, with a bar for success being measurable changes in retinal thickness [65][66] Financial Strategy - **Debt Management**: Paid down $75 million in Pharmakon debt, with a remaining debt of $249 million and a cash position of approximately $240 million [68] - **Future Investments**: Plans to continue paying down debt while investing in the pipeline and potential business development opportunities [68] Key Takeaways - BioCryst is positioned for growth with a strong financial outlook and promising drug pipeline focused on rare diseases - The company is actively pursuing regulatory approvals for pediatric indications and expanding its clinical trials for Netherton Syndrome and DME - Financial health is robust, allowing for continued investment in research and development while managing debt effectively [5][68]

Core Viewpoint - Momentum investing focuses on following a stock's recent price trends, aiming to buy high and sell higher, with the expectation that established trends will continue [1] Company Overview: BioCryst Pharmaceuticals (BCRX) - BioCryst Pharmaceuticals currently holds a Momentum Style Score of B, indicating a favorable momentum characteristic [2] - The company has a Zacks Rank of 1 (Strong Buy), suggesting strong potential for outperformance in the market [3] Performance Metrics - BCRX shares have increased by 1.51% over the past week, while the Zacks Medical - Drugs industry remained flat during the same period [5] - Over the last month, BCRX's price change is 8.96%, outperforming the industry's 3.76% [5] - In the past quarter, BCRX shares have surged by 48.41%, and over the last year, they have gained 66.02%, compared to the S&P 500's increases of 2.37% and 14.4%, respectively [6] Trading Volume - The average 20-day trading volume for BCRX is 4,994,540 shares, which serves as a bullish indicator when combined with rising stock prices [7] Earnings Outlook - In the last two months, 6 earnings estimates for BCRX have been revised upwards, with no downward revisions, leading to an increase in the consensus estimate from -$0.06 to $0.16 [9] - For the next fiscal year, 6 estimates have also moved upwards without any downward revisions [9] Conclusion - Considering the positive performance metrics and earnings outlook, BCRX is positioned as a 1 (Strong Buy) stock with a Momentum Score of B, making it a potential candidate for near-term investment [11]