Core Insights - The SURPASS-CVOT study represents a significant advancement in the treatment of type 2 diabetes, demonstrating the cardiovascular benefits of the dual GIP/GLP-1 receptor agonist tirzepatide compared to the GLP-1 receptor agonist dulaglutide [2][3] - Tirzepatide shows improvements in A1C levels, weight, renal function, and all-cause mortality, indicating its potential for broader applications in managing diabetes and cardiovascular risks [2][3] - The study included over 13,000 adult patients with type 2 diabetes and atherosclerotic cardiovascular disease from 30 countries, making it the largest and longest follow-up study of tirzepatide to date [3] Company and Industry Implications - The results of the SURPASS-CVOT study provide solid evidence for the cardiovascular benefits and long-term safety of tirzepatide, which may lead to its wider adoption among diabetes patients in China [3][4] - The high cost of treating cardiovascular diseases and chronic complications accounts for 87.05% of the total medical expenditure for diabetes in China, highlighting the need for innovative treatments like tirzepatide to alleviate the healthcare burden [3][4] - Eli Lilly's commitment to patient-centered care and clinical value is evident in their ongoing research efforts, with plans to submit detailed results to global regulatory agencies by the end of the year [4]
礼来又一里程碑式头对头研究公布结果 替尔泊肽控糖、减重、心肾保护“多效合一”