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礼来拿到“药王”头衔!CEO戴文睿与黄仁勋深度对话:当生物医药“手工艺式的发现”正在变成一个工程问题……
聪明投资者· 2026-02-06 03:32
以下文章来源于IN咖 ,作者聪明投资者 IN咖 . 多视角关注优秀投资人和企业家 1. 生物医药 行业长期受到一个问题的困扰:创新周期往往比回报周期更长。 2. 在几乎所有治疗领域里,礼来的整体研发速度,平均仍然比下一家同规模的制药公司快大约 40%。 3. CEO的工作 职责 是创造条件,让伟大的想法能够系统性地不断涌现。 4. 在过去 10年里,我当初做过的一个最重要的决定,就是在公司还负担不起的时候,依然为英伟达建造了 一台当时全球规模最大的超级计算机之一。 5. 我 现在 真的认为, 生物医药 行业的 " 关键 时刻 "已经到来了。能够从"药物发现"这种有点像在森林 里找松露的方式,转向真正的计算机辅助药物设计。 6. 当然,这背后的科学极其复杂,人类生物学本身也极其复杂,可能 (完全实现) 还需要 10 年时间。 7. 如果我们能把这件事从一种 "手工艺式的发现",变成一个工程问题,那对人类生命的影响将是巨大的。 8. 我们更关注一个更现实的问题:如果最大寿命上限是 100岁,我们怎么让更多人更有机会真正走到那一 天?而我们的方式,是通过消除疾病来实现这一点。 9. 如果说在 AI领域目前最容易落地 ...
“药王”大变局
3 6 Ke· 2026-02-06 00:42
365.07亿美元。 随着礼来公布2025年财报,替尔泊肽以这一惊人销售额,正式加冕为新一代全球药王。 不得不再次感慨GLP-1的吸金实力。曾经的热门选手司美格鲁肽(361亿美元)也仅以4亿美元之差,与 药王失之交臂。而随着药王竞争的空前白热化,曾经的"王者"修美乐曾蝉联十年,而K药仅在位两年便 黯然退场。 / 01 /GLP-1时代正式加冕 药王的每一次更迭,都标志着一个治疗时代的开启。2025年,这个时代属于GLP-1,更具体地说,属于 礼来的替尔泊肽。 根据礼来财报,替尔泊肽在2025年狂揽365.07亿美元,其中降糖版Mounjaro贡献229.65亿美元,减肥版 Zepbound贡献135.42亿美元。其第四季度表现尤为炸裂,Mounjaro单季营收74亿美元,同比增长 110%,远超此前66亿美元的预期;Zepbound同样超出预期,营收达43亿美元,同比增长123%。 基于替尔泊肽的强劲增长,礼来为2026年给出了800亿至830亿美元的全年营收指引,尽管增速相比2025 年的41%有所放缓,但依然是一条颇为陡峭的增长曲线。这也预示着,替尔泊肽已提前预定了2026年全 球药王的宝座。 替尔泊肽的 ...
诺和诺德暴跌8%,新减肥药片刚上市就遭"山寨",远程医疗公司Hims推出49美元仿制药
Hua Er Jie Jian Wen· 2026-02-05 23:10
诺和诺德刚刚推出的减肥药片尚未站稳脚跟,就遭遇了一场意料之外的市场挑战。 2月5日周四,诺和诺德股价重挫,此前远程医疗公司Hims & Hers Health推出了诺和诺德减肥药Wegovy片剂的仿制版本, 定价仅为首月49美元,随后每月99美元,远低于诺和诺德的品牌药物149美元的起始月费。 诺和诺德本希望借助新品扭转颓势,但远程医疗公司推出的低价仿制版本迅速搅乱了市场格局,引发了关于药品专利保护 和监管框架的激烈交锋。 诺和诺德发表声明称,Hims此举属于"非法大规模复配,对患者构成重大风险"。公司表示,将采取法律和监管行动,以 保护患者、公司知识产权以及美国药品审批框架的完整性。 受此消息冲击,周四诺和诺德ADR股价跌超8%,竞争对手礼来公司也下跌7.1%。 远程医疗公司抢滩低价市场 Hims的仿制药片对诺和诺德的产品构成威胁。 据路透社报道,这款仿制品采用了"不同的配方和给药系统",Hims发言人Abby Reisinger表示: 今天提供的复配司美格鲁肽片剂不是Wegovy的本质复制品。 尽管供应短缺已经结束,远程医疗公司本应停止销售仿制品,但它们通过调整剂量或添加成分,使产品被视为与品牌药物 足够 ...
纳指连续三天跌超1%,亚马逊盘后跳水超10%,中概股逆势走强
Feng Huang Wang· 2026-02-05 23:04
(来源:TradingView) 昨夜今晨,近几天命途多舛的软件板块和加密货币再度迎来新一轮的下挫。疲软的美国就业数据也令过去几天的"板块轮动"戛然而止,抛售范围扩大到整个 市场。 截至收盘,标普500指数跌1.23%,报6798.4点;纳斯达克综合指数跌1.59%,报22540.59点,也是自去年4月以来最严重的三日抛售;道琼斯工业平均指数跌 1.2%,报48908.72点。比特币盘中跌破6.4万美元,近半年缩水近一半;现货白银也出现了单日下跌近20%的状况。 前几个交易日,美股的下跌局限在AI和软件相关的板块,周四抛售范围进一步扩大。标普500成分股中有318只个股下跌,部分原因在于最新劳动力市场数 据疲软。其中美国12月职位空缺意外下降至2020年以来的最低水平。挑战者裁员人数创下自2009年衰退最严重时期以来的1月最高纪录。 安联首席经济顾问Mohamed El-Erian表示:"值得注意的是,这些裁员发生在GDP仍以约 4%速度增长的情况下,加速了就业与经济增长的脱钩——如果这一 现象持续下去,将产生深远的经济、政治和社会影响。" 周四收盘后,标普500指数又一次踩在100日均线上。令市场感到焦心的 ...
Eli Lilly: Positives Outweigh The Concerns
Seeking Alpha· 2026-02-05 22:28
Manika is a macroeconomist with over 20 years of experience in industries including investment management, stock broking, investment banking. She also runs the profile Long Term Tips [LTT], which focuses on the generational opportunity in the green economy. Her investing group, Green Growth Giants, takes the theme a step further from LTT with a deeper dive into opportunities presented by the segment.Analyst’s Disclosure: I/we have no stock, option or similar derivative position in any of the companies menti ...
Eli Lilly (NYSE:LLY) Faces Competitive Pressure but Holds Strong Growth Potential
Financial Modeling Prep· 2026-02-05 22:16
Core Viewpoint - Eli Lilly's stock is facing competitive pressure due to Hims & Hers launching a cheaper version of the Wegovy pill, despite a positive long-term price target set by Scotiabank at $1,300, indicating a potential rise of 25.35% from its current trading price [1][2][6] Company Performance - Eli Lilly's current stock price is $1,025.08, reflecting a decrease of 7.41%, which is a drop of $82.04 from previous levels [4] - The stock's trading range for the day was between $1,018.82 and $1,073.49, with a market capitalization of approximately $918.94 billion [4] Competitive Landscape - Hims & Hers' announcement to launch a cheaper version of the Wegovy pill has led to a 6.1% decline in Eli Lilly's stock price, indicating increased competitive pressure in the market [2] - Novo Nordisk, a key competitor, also experienced a 7% drop in its shares following the same announcement, despite having 170,000 users for the Wegovy pill in the U.S. [3] Market Sentiment - Despite the recent decline in stock price, Scotiabank's price target reflects optimism for Eli Lilly's long-term growth potential, emphasizing the importance of the company's ability to navigate competitive challenges [5][6]
Tech Sell-Off Drags Major Indexes Lower as Job Market Woes Persist; Alphabet, Qualcomm Tumble
Stock Market News· 2026-02-05 22:07
U.S. equities experienced a challenging day on Thursday, February 5, 2026, as a significant sell-off in technology stocks and discouraging reports from the job market weighed heavily on investor sentiment. The tech-heavy Nasdaq Composite (NDAQ) and the benchmark S&P 500 (SPX) both closed sharply lower, marking their third consecutive day of losses, while the Dow Jones Industrial Average (DJIA) also retreated amidst a broad "risk-off" environment.The S&P 500 fell 1.2% to close at 6,798.40, recording its sixt ...
Hims & Hers Launches New Pill That Sends Shockwaves Across Weight-Loss Drugmakers' Stocks
Investopedia· 2026-02-05 21:27
-- Hims & Hers Launches New Pill That Sends Shockwaves Across Weight-Loss Drugmakers' Stocks [Stocks Tumble for 3rd Straight Day][Is the Tech Stock Sell-Off 'Healthy'?][Bitcoin Continues Its Dramatic Decline] [The Job Market Freeze Has Deepened This Winter]- Top StoriesHims & Hers Health said its new weight-loss pill comes with same active ingredient as Novo Nordisk's Wegovy.Hims & HersClose### Key Takeaways- Shares of Eli Lilly and Novo Nordisk tumbled following the announcement, while Hims & Hers shares i ...
Why a $49 weight-loss pill is rattling Novo Nordisk and Eli Lilly
Invezz· 2026-02-05 19:29
Novo Nordisk and Eli Lilly are facing an uncomfortable new price point this week after a $49 weight-loss pill jolted the GLP-1 market. By launching a low-cost, compounded oral version of semaglutide, ... ...
Eli Lilly's 2026 Outlook Push Back Demand Fears: Analyst
Benzinga· 2026-02-05 18:44
Eli Lilly and Co. (NYSE:LLY) stock is trading lower on Thursday, possibly on profit-taking after the stock rallied roughly 10% on Wednesday.On Wednesday, Eli Lilly reported fourth-quarter adjusted earnings of $7.54 per share, beating the consensus of $6.67.The company’s sales reached $19.3 billion, beating the consensus of $17.96 billion.The obesity drug maker expects sales between $80 billion-$83 billion compared to the Wall Street estimate of $77.62 billion.Eli Lilly sees fiscal 2026 adjusted earnings of ...