OPK Stock Slips Following Q2 Earnings Miss, Gross Margin Expands

Core Insights - OPKO Health, Inc. reported a loss per share of 19 cents in Q2 2025, which is wider than the previous year's loss of 1 cent and the Zacks Consensus Estimate of a loss of 12 cents [2][11] - The company's revenues for the second quarter were $156.8 million, reflecting a 13.9% year-over-year decline and missing the Zacks Consensus Estimate by 5.1% [3][11] Revenue Breakdown - Revenues from the Diagnostics segment amounted to $101.1 million, down 21.9% year-over-year, primarily due to lower clinical test volumes following the sale of certain BioReference assets [5] - In the Pharmaceuticals segment, product revenues increased by 0.6% year-over-year to $40.7 million, driven by higher sales volumes in international operations, although offset by reduced sales in Chile [6] - Revenue from the transfer of intellectual property and other reached $14.9 million, up 21.6% year-over-year, attributed to higher revenue from the BARDA contract [8] Margin and Expense Analysis - Gross profit decreased by 4.4% year-over-year to $49.4 million, but gross margin improved by 315 basis points to 31.5% [9][11] - Selling, general and administrative (SG&A) expenses fell by 13.4% year-over-year to $59.6 million, while research and development expenses rose by 25.9% to $30.3 million [9] Financial Position - At the end of Q2 2025, OPKO Health had cash and cash equivalents of $271.7 million, down from $435.9 million at the end of Q1 2025 [12] - Cumulative net cash used in operating activities increased to $117.9 million compared to $62 million a year ago [12] Guidance and Outlook - OPKO Health revised its 2025 revenue outlook to a range of $640 million to $660 million, down from a previous estimate of $675 million to $685 million [13] - Expected revenues from product sales are now projected between $160 million and $170 million, and revenues from services are anticipated to be in the range of $405 million to $425 million [14] Additional Developments - OPKO Health's ModeX is advancing its immuno-oncology and immunology portfolio with four potential clinical candidates, and the FDA approved a supplemental application for the 4KScore Test [16]