Opko Health Inc. (NASDAQ:OPK) is one of the best stocks under $3 to invest in. On February 4, Opko Health Inc. (NASDAQ:OPK) announced it expanded its partnership with Entera Bio Ltd., a company developing oral peptide and protein replacement therapies, to advance the first oral long-acting PTH analog (LA-PTH) treatment for patients with hypoparathyroidism, in the form of a once-daily tablet. The two companies have also jointly decided to accelerate development on this medication and expect to file an Inves ...

This is the third program that successfully combines Entera’s oral peptide N-Tab® platform with OPKO’s advanced protein chemistry capabilities The companies have accelerated this program and aim to file an investigational new drug (IND) application in late 2026 Injectable and oral oxyntomodulin (dual GLP-1/glucagon analog) for metabolic and fibrotic disorders advancing with initial Phase 1 data from injectable oxyntomodulin (OXM) expected in late 2026; oral OXM to enter clinic thereafter Industry veteran St ...

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OPKO Health Conference Call Summary Company Overview - **Company**: OPKO Health - **Key Participants**: - Elias Zerhouni - President - Adam Logal - CFO - **Industry**: Biotechnology and Clinical Diagnostics Core Business Components - OPKO Health operates a diverse range of businesses, including: - Clinical diagnostics through BioReference Health - Biotech operations via ModeX Therapeutics, focusing on therapeutics and divesting from clinical diagnostics to improve profitability [6][15] Financial Performance and Strategy - OPKO has divested approximately 40% of its clinical diagnostic business to enhance profitability, focusing on operations in New York and New Jersey [6][15] - The company is nearing break-even and profitability with its remaining clinical diagnostic business, particularly with the 4Kscore cancer diagnostic test, which has shown over 15% growth in testing [7][17] - Guidance for 2026 indicates a projected revenue growth of 3%-5% from a base of approximately $300 million, with a focus on operating efficiency rather than deep investment in commercial operations [18] Key Products and Developments - **4Kscore Test**: - Aids in identifying patients at high risk for aggressive prostate cancer, with a market potential of $25-$30 million [20][21] - Recently received FDA clearance to remove the requirement for a digital rectal exam, potentially increasing adoption [21] - **ModeX Therapeutics**: - Licensed an Epstein-Barr Virus (EBV) vaccine to Merck for $50 million upfront and potential milestones of $870 million [9][10] - The vaccine is in phase one trials, with significant potential for treating cancer and multiple sclerosis [10][25] - **Pipeline Products**: - MDX-2001: A cancer solid tumor product nearing phase 1B trials, targeting multiple cancer types [11][32] - MDX-2004: A trispecific antibody aimed at rejuvenating the immune system, currently in clinical trials [12][42] - Collaboration with Regeneron to develop multiple programs in obesity, metabolism, and cancer [13][52] Milestones and Future Outlook - The company anticipates significant milestones tied to the progression of its vaccine and therapeutic candidates, with potential financial milestones upon entering phase two trials [27][31] - The partnership with Regeneron is expected to yield candidates by the end of the year or early next year, with a focus on combination therapies [53][54] Risk Management and Clinical Trials - OPKO is managing risks associated with clinical trials, particularly concerning cytokine release syndrome (CRS) through established protocols and dose management strategies [36][39] - The company is focused on ensuring safety and efficacy in its trials, with ongoing assessments to determine the most responsive cancer types for its therapies [32][35] Conclusion - OPKO Health is strategically repositioning itself towards a more therapeutics-focused model while maintaining a profitable clinical diagnostics segment. The company is poised for growth with a rich pipeline of products and strategic partnerships that could lead to significant advancements in the biotech space over the next few years [15][30]

MIAMI, Jan. 06, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (Nasdaq: OPK) announced today that management will be participating in the 44th Annual J.P. Morgan Healthcare Conference, being held January 12-15, 2026, at the Westin St. Francis Hotel in San Francisco. Management will be hosting one-on-one meetings with investors and will be participating in a fireside chat on Wednesday, January 14th at 1:30 p.m. Pacific time. The fireside chat will be webcast live and available for replay in the Investors section ...

Core Viewpoint - OPKO Health, Inc. will participate in the 44th Annual J.P. Morgan Healthcare Conference, indicating its active engagement with investors and the healthcare community [1] Company Participation - Management will host one-on-one meetings with investors during the conference [1] - A fireside chat is scheduled for January 14th at 1:30 p.m. Pacific time, which will be webcast live and available for replay [1][2] Company Overview - OPKO Health is a multinational biopharmaceutical and diagnostics company focused on establishing industry-leading positions in large, rapidly growing markets [3] - The company leverages its expertise in discovery, development, and commercialization, along with novel and proprietary technologies [3]

Core Viewpoint - OPKO Health, Inc. is positioned for growth driven by the potential of its flagship product RAYALDEE, despite facing competition and reliance on this single product [2][4][16] Company Overview - OPKO Health has a market capitalization of $974.9 million and anticipates a 30% growth for fiscal 2026, maintaining strong performance [3] - The company has experienced mixed earnings results, surpassing estimates in two of the last four quarters with an average beat of 58.52% [3] Factors Favoring OPK Stock - RAYALDEE is the first FDA-approved treatment for secondary hyperparathyroidism in adults with stage 3 or 4 chronic kidney disease, showing solid commercial traction [4] - The company recorded net product revenues of $7.5 million and $21.0 million from RAYALDEE sales for the three- and nine-month periods ended September 30, 2025 [5] - Strategic partnerships, including a collaboration with Regeneron Pharmaceuticals for multispecific antibodies, are aimed at strengthening OPKO's operational focus [6][9] Clinical Programs and Developments - OPKO Health is advancing multiple clinical programs, including a Phase 1/2a trial for MDX2004, a trispecific antibody-fusion protein for oncology [11] - The company is also progressing with its Epstein-Barr virus vaccine program in collaboration with Merck, which has entered Phase 1 human studies [13] - An oral GLP-2 tablet for treating short bowel syndrome is being developed in collaboration with Entera Bio, targeting gastrointestinal conditions [15] Financial Estimates and Trends - The Zacks Consensus Estimate for OPKO's loss per share for 2026 remains stable at 24 cents, with first-quarter 2026 revenue estimates at $130.9 million, indicating a 12.6% decline from the previous year [17]

Key Takeaways OPKO Health is positioned for growth with RAYALDEE performance and multiple partnership-driven initiatives.RAYALDEE maintained sales strength supported by rebates, discounts and broad U.S. distribution channels.Clinical programs advanced with new oncology, vaccine and metabolic trials and continued data presentations.OPKO Health, Inc. (OPK) is well-poised for growth in the coming quarters, supported by the potential of RAYALDEE. The optimism surrounding the stock is backed by RAYALDEE’s perfor ...

Core Insights - OPKO Health, Inc. will participate in the Piper Sandler 37th Annual Healthcare Conference from December 2-4, 2025, in New York City [1] - Management will hold one-on-one meetings with investors and participate in a fireside discussion on December 3 at 12:00 p.m. Eastern time [1] Company Overview - OPKO Health is a multinational biopharmaceutical and diagnostics company focused on establishing industry-leading positions in large, rapidly growing markets [3] - The company leverages its discovery, development, and commercialization expertise along with novel and proprietary technologies [3]