【人民日报】中国科学院团队实现染色体“精准编辑”

Core Insights - The rapid development and widespread application of genome editing technology in the life sciences provide strong technical support for basic research and application development [1] - A new programmable chromosome editing technology developed by a team from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, enables precise manipulation of DNA from kilobases to megabases in plants and animals [1] - This technology significantly enhances the scale and capability of manipulating eukaryotic genomes, representing a major breakthrough in the field of genetic engineering [1] Summary by Categories Technology Development - The new technology allows for multi-gene stacking editing and manipulation of genomic structural variations, opening new pathways for crop trait improvement and genetic disease treatment [1] - It is expected to promote the development of new breeding strategies by manipulating genetic linkage and controlling recombination frequency [1] Applications - The technology has the potential to eliminate linkage drag and fully unleash the breeding potential of superior alleles in wild germplasm resources [1] - Reviewers have noted the significant application potential of this work in breeding and gene therapy [1]